GO Term : GO:0034649 histone demethylase activity (H3-monomethyl-K4 specific) GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 4) + O2 + FAD + H2O = histone H3 L-lysine (position 4) + H2O2 + formaldehyde + FADH2. This reaction is the removal of a methyl group from monomethylated lysine at position 4 of the histone H3 protein.

0 Cross References

1 Ontology

Name
GO

8 Parents

Identifier Name Description
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0032451 demethylase activity Catalysis of the removal of a methyl group from a substrate.
GO:0032452 histone demethylase activity Catalysis of the removal of a methyl group from a histone.
GO:0032453 histone demethylase activity (H3-K4 specific) Catalysis of the removal of a methyl group from lysine at position 4 of the histone H3 protein.
GO:0034649 histone demethylase activity (H3-monomethyl-K4 specific) Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 4) + O2 + FAD + H2O = histone H3 L-lysine (position 4) + H2O2 + formaldehyde + FADH2. This reaction is the removal of a methyl group from monomethylated lysine at position 4 of the histone H3 protein.

0 Protein

7 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0032453 GO:0034649
is_a GO:0016705 GO:0034649
is_a GO:0003674 GO:0034649
is_a GO:0032452 GO:0034649
is_a GO:0032451 GO:0034649
is_a GO:0016491 GO:0034649
is_a GO:0003824 GO:0034649

1 Synonyms

Name Type
histone demethylase activity (H3-K4-me1 specific) synonym