GO Term : GO:0061659 ubiquitin-like protein ligase activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S --> X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate.

0 Cross References

1 Ontology

Name
GO

5 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0019787 ubiquitin-like protein transferase activity Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y --> Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein.
GO:0061659 ubiquitin-like protein ligase activity Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S --> X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate.

0 Protein

17 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0061659 GO:0034450
is_a GO:0061659 GO:0061630
is_a GO:0019787 GO:0061659
is_a GO:0003674 GO:0061659
is_a GO:0003824 GO:0061659
is_a GO:0016740 GO:0061659
is_a GO:0061659 GO:0061660
is_a GO:0061659 GO:0061661
is_a GO:0061659 GO:0061662
is_a GO:0061659 GO:0061663
is_a GO:0061659 GO:0061664
is_a GO:0061659 GO:0061665
is_a GO:0061659 GO:0061666
is_a GO:0061659 GO:0061667
is_a GO:0061659 GO:0090302
is_a GO:0061659 GO:0090622
is_a GO:0061659 GO:1904264

2 Synonyms

Name Type
E3 synonym
small conjugating protein ligase activity synonym