GO Term : GO:0033503 HULC complex GO

Namespace  cellular_component Obsolete  false
description  A ubiquitin-conjugating enzyme complex that contains two RING finger proteins, which have ubiquitin ligase activity, in addition to a protein with ubiquitin-conjugating enzyme activity; catalyzes the ubiquitination of histone H2B at lysine 119 (or the equivalent residue). In Schizosaccharomyces the subunits are Rhp1, Brl2/Rfp1 and Brl1/Rfp2.

0 Cross References

1 Ontology

Name
GO

22 Parents

Identifier Name Description
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0005694 chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
GO:0043234 protein complex A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
GO:0000785 chromatin The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
GO:1902494 catalytic complex A protein complex which is capable of catalytic activity.
GO:0044424 intracellular part Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0032991 macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0044422 organelle part Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
GO:0044446 intracellular organelle part A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
GO:0043226 organelle Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
GO:0043229 intracellular organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0043228 non-membrane-bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
GO:0043232 intracellular non-membrane-bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
GO:1990234 transferase complex A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor).
GO:0000151 ubiquitin ligase complex A protein complex that includes a ubiquitin-protein ligase and other proteins that may confer substrate specificity on the complex.
GO:0044427 chromosomal part Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
GO:0000792 heterochromatin A compact and highly condensed form of chromatin.
GO:0031371 ubiquitin conjugating enzyme complex Any complex that possesses ubiquitin conjugating enzyme activity.
GO:0033503 HULC complex A ubiquitin-conjugating enzyme complex that contains two RING finger proteins, which have ubiquitin ligase activity, in addition to a protein with ubiquitin-conjugating enzyme activity; catalyzes the ubiquitination of histone H2B at lysine 119 (or the equivalent residue). In Schizosaccharomyces the subunits are Rhp1, Brl2/Rfp1 and Brl1/Rfp2.

0 Protein

28 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0000792 GO:0033503
is_a GO:0000151 GO:0033503
is_a GO:0044427 GO:0033503
is_a GO:0031371 GO:0033503
is_a GO:0043234 GO:0033503
is_a GO:1990234 GO:0033503
part of GO:0032991 GO:0033503
part of GO:0044446 GO:0033503
is_a GO:0044446 GO:0033503
part of GO:0044422 GO:0033503
is_a GO:1902494 GO:0033503
part of GO:0044424 GO:0033503
part of GO:0005694 GO:0033503
part of GO:0000785 GO:0033503
part of GO:0044464 GO:0033503
part of GO:0043228 GO:0033503
is_a GO:0044464 GO:0033503
part of GO:0043229 GO:0033503
part of GO:0005575 GO:0033503
is_a GO:0044422 GO:0033503
is_a GO:0044424 GO:0033503
part of GO:0005622 GO:0033503
part of GO:0005623 GO:0033503
is_a GO:0005575 GO:0033503
part of GO:0043232 GO:0033503
part of GO:0043226 GO:0033503
is_a GO:0032991 GO:0033503
part of GO:0044427 GO:0033503

0 Synonyms