GO Term : GO:0030697 S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing thymine at position U54 of a transfer RNA. This occurs in most Gram-negative bacteria, some archae, and eukaryotes.

0 Cross References

1 Ontology

Name
GO

11 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0008168 methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.
GO:0008173 RNA methyltransferase activity Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0016741 transferase activity, transferring one-carbon groups Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor).
GO:0008175 tRNA methyltransferase activity Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule.
GO:0016300 tRNA (uracil) methyltransferase activity Catalysis of the transfer of a methyl group from a donor to a uracil residue in a tRNA molecule.
GO:0030696 tRNA (m5U54) methyltransferase activity Catalysis of the transfer of a methyl group from a donor to the C5 atom of the uridine residue at position 54 in a tRNA molecule.
GO:0030697 S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing thymine at position U54 of a transfer RNA. This occurs in most Gram-negative bacteria, some archae, and eukaryotes.

0 Protein

10 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0008757 GO:0030697
is_a GO:0030696 GO:0030697
is_a GO:0003674 GO:0030697
is_a GO:0016300 GO:0030697
is_a GO:0016740 GO:0030697
is_a GO:0003824 GO:0030697
is_a GO:0008168 GO:0030697
is_a GO:0016741 GO:0030697
is_a GO:0008173 GO:0030697
is_a GO:0008175 GO:0030697

13 Synonyms

Name Type
RUMT synonym
S-adenosyl-L-methionine:tRNA (uracil-5-)-methyltransferase activity synonym
S-adenosyl methionine-dependent tRNA (m5U54) methyltransferase activity synonym
RUMT activity synonym
ribothymidyl synthase activity synonym
M5U-methyltransferase activity synonym
tRNA uracil 5-methyltransferase activity synonym
tRNA (uracil-5-)-methyltransferase activity synonym
transfer RNA uracil methylase activity synonym
transfer RNA uracil 5-methyltransferase activity synonym
GO:0009021 alt_id
tRNA:m5U54-methyltransferase activity synonym
tRNA:m(5)U54-methyltransferase activity synonym