GO Term : GO:0004362 glutathione-disulfide reductase activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+.

0 Cross References

1 Ontology

Name
GO

11 Parents

Identifier Name Description
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016651 oxidoreductase activity, acting on NAD(P)H Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces NAD or NADP.
GO:0016209 antioxidant activity Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0016667 oxidoreductase activity, acting on a sulfur group of donors Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0004362 glutathione-disulfide reductase activity Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+.
GO:0015038 glutathione disulfide oxidoreductase activity Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor.
GO:0015036 disulfide oxidoreductase activity Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.
GO:0015037 peptide disulfide oxidoreductase activity Catalysis of the reaction: a peptide with reduced sulfide groups = a peptide with oxidized disulfide bonds.

0 Protein

10 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016209 GO:0004362
is_a GO:0015038 GO:0004362
is_a GO:0016668 GO:0004362
is_a GO:0016491 GO:0004362
is_a GO:0003674 GO:0004362
is_a GO:0016651 GO:0004362
is_a GO:0003824 GO:0004362
is_a GO:0015036 GO:0004362
is_a GO:0016667 GO:0004362
is_a GO:0015037 GO:0004362

11 Synonyms

Name Type
oxidized glutathione reduction synonym
NADPH:oxidized-glutathione oxidoreductase activity synonym
NADPH-GSSG reductase activity synonym
NADPH-glutathione reductase activity synonym
GSSG reductase activity synonym
GSH reductase activity synonym
glutathione:NADP+ oxidoreductase activity synonym
glutathione-disulphide reductase activity synonym
glutathione S-reductase activity synonym
glutathione reductase activity synonym
glutathione reductase (NADPH) activity synonym