GO Term : GO:0004355 glutamate synthase (NADPH) activity GO
Namespace  molecular_function Obsolete  false
description  Catalysis of the reaction: 2 L-glutamate + NADP(+) = 2-oxoglutarate + L-glutamine + H(+) + NADPH. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + NADP+ + H2O = NH3 + 2-oxoglutarate + NADPH + H+.
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0 Cross References

1 Ontology

Name
GO

8 Parents

Identifier Name Description
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0015930 glutamate synthase activity Catalysis of the formation of L-glutamine and 2-oxoglutarate from L-glutamate, using NADH, NADPH or ferredoxin as hydrogen acceptors.
GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
GO:0045181 glutamate synthase activity, NAD(P)H as acceptor Catalysis of the reaction: 2 L-glutamate + NAD(P)+ = L-glutamine + 2-oxoglutarate + NAD(P)H + H+.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0004355 glutamate synthase (NADPH) activity Catalysis of the reaction: 2 L-glutamate + NADP(+) = 2-oxoglutarate + L-glutamine + H(+) + NADPH. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + NADP+ + H2O = NH3 + 2-oxoglutarate + NADPH + H+.

0 Protein

7 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0045181 GO:0004355
is_a GO:0003824 GO:0004355
is_a GO:0015930 GO:0004355
is_a GO:0016639 GO:0004355
is_a GO:0003674 GO:0004355
is_a GO:0016638 GO:0004355
is_a GO:0016491 GO:0004355

12 Synonyms

Name Type
glutamate synthetase (NADP) activity synonym
glutamine amide-2-oxoglutarate aminotransferase (oxidoreductase, NADP) activity synonym
glutamate (reduced nicotinamide adenine dinucleotide phosphate) synthase activity synonym
L-glutamate:NADP+ oxidoreductase (transaminating) synonym
L-glutamine:2-oxoglutarate aminotransferase, NADPH oxidizing activity synonym
L-glutamate synthase activity synonym
glutamine-ketoglutaric aminotransferase activity synonym
L-glutamate synthetase activity synonym
GOGAT activity synonym
NADPH-linked glutamate synthase synonym
NADPH-dependent glutamate synthase activity synonym
NADPH-glutamate synthase activity synonym