GO Term : GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R.

0 Cross References

1 Ontology

Name
GO

6 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016757 transferase activity, transferring glycosyl groups Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0008373 sialyltransferase activity Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R.

0 Protein

5 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0008373 GO:0003828
is_a GO:0003674 GO:0003828
is_a GO:0016740 GO:0003828
is_a GO:0016757 GO:0003828
is_a GO:0003824 GO:0003828

10 Synonyms

Name Type
CMP-NeuAc:LM1 alpha-(2->8)-sialyltranferase activity synonym
CMP-NeuAc:LM1(alpha-2,8) sialyltranferase activity synonym
cytidine monophosphoacetylneuraminate-ganglioside GM3 synonym
ganglioside GD3 synthase activity synonym
ganglioside GD3 synthetase sialyltransferase activity synonym
GD3 synthase activity synonym
SAT-2 synonym
CMP-N-acetylneuraminate:alpha-N-acetylneuraminyl-2,3-beta-D-galactoside alpha-2,8-N-acetylneuraminyltransferase activity synonym
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase activity synonym
alpha-2,8-sialyltransferase activity synonym