GO Term : GO:0000122 negative regulation of transcription from RNA polymerase II promoter GO
Namespace  biological_process Obsolete  false
description  Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
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0 Cross References

1 Ontology

Name
GO

67 Parents

Identifier Name Description
GO:0006355 regulation of transcription, DNA-templated Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016070 RNA metabolic process The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
GO:0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0006351 transcription, DNA-templated The cellular synthesis of RNA on a template of DNA.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0006357 regulation of transcription from RNA polymerase II promoter Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
GO:0006366 transcription from RNA polymerase II promoter The synthesis of RNA from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
GO:0006139 nucleobase-containing compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0044249 cellular biosynthetic process The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GO:0010468 regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
GO:0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0045892 negative regulation of transcription, DNA-templated Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
GO:0006725 cellular aromatic compound metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0051252 regulation of RNA metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0090304 nucleic acid metabolic process Any cellular metabolic process involving nucleic acids.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0046483 heterocycle metabolic process The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
GO:0034641 cellular nitrogen compound metabolic process The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
GO:1901360 organic cyclic compound metabolic process The chemical reactions and pathways involving organic cyclic compound.
GO:0019219 regulation of nucleobase-containing compound metabolic process Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0031323 regulation of cellular metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
GO:0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.

0 Protein

156 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
negatively regulates GO:0006366 GO:0000122
is_a GO:0006357 GO:0000122
is_a GO:0045892 GO:0000122
is_a GO:0060255 GO:0000122
regulates GO:0097659 GO:0000122
negatively regulates GO:0046483 GO:0000122
negatively regulates GO:0008150 GO:0000122
regulates GO:1901362 GO:0000122
regulates GO:0032774 GO:0000122
regulates GO:1901360 GO:0000122
negatively regulates GO:0008152 GO:0000122
is_a GO:0050789 GO:0000122
negatively regulates GO:0009987 GO:0000122
negatively regulates GO:0010467 GO:0000122
is_a GO:0065007 GO:0000122
regulates GO:0034641 GO:0000122
negatively regulates GO:0019438 GO:0000122
negatively regulates GO:0034654 GO:0000122
regulates GO:0006139 GO:0000122
negatively regulates GO:0006351 GO:0000122
is_a GO:1902679 GO:0000122
regulates GO:0034645 GO:0000122
is_a GO:0010468 GO:0000122
is_a GO:0010629 GO:0000122
negatively regulates GO:0044249 GO:0000122
regulates GO:0044249 GO:0000122
is_a GO:0051253 GO:0000122
is_a GO:0051252 GO:0000122
is_a GO:0010558 GO:0000122
is_a GO:0010556 GO:0000122

14 Synonyms

Name Type
inhibition of transcription from RNA polymerase II promoter synonym
negative regulation of gene-specific transcription from RNA polymerase II promoter synonym
downregulation of transcription from RNA polymerase II promoter synonym
inhibition of global transcription from RNA polymerase II promoter synonym
negative regulation of transcription from RNA polymerase II promoter, global synonym
GO:0010553 alt_id
negative regulation of global transcription from Pol II promoter synonym
negative regulation of transcription from Pol II promoter synonym
down regulation of global transcription from RNA polymerase II promoter synonym
GO:0045816 alt_id
down-regulation of transcription from RNA polymerase II promoter synonym
downregulation of global transcription from RNA polymerase II promoter synonym
down regulation of transcription from RNA polymerase II promoter synonym
down-regulation of global transcription from RNA polymerase II promoter synonym