GO Term : GO:0045892 negative regulation of transcription, DNA-templated GO
Namespace  biological_process Obsolete  false
description  Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
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0 Cross References

1 Ontology

Name
GO

64 Parents

Identifier Name Description
GO:0006355 regulation of transcription, DNA-templated Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016070 RNA metabolic process The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
GO:0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0006351 transcription, DNA-templated The cellular synthesis of RNA on a template of DNA.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0006139 nucleobase-containing compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0044249 cellular biosynthetic process The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GO:0010468 regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
GO:0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0045892 negative regulation of transcription, DNA-templated Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
GO:0006725 cellular aromatic compound metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0051252 regulation of RNA metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0090304 nucleic acid metabolic process Any cellular metabolic process involving nucleic acids.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0046483 heterocycle metabolic process The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
GO:0034641 cellular nitrogen compound metabolic process The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
GO:1901360 organic cyclic compound metabolic process The chemical reactions and pathways involving organic cyclic compound.
GO:0019219 regulation of nucleobase-containing compound metabolic process Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0031323 regulation of cellular metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
GO:0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

2 Protein

Protein Identifier
Organism . Name 		Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0307580.2 Quercus robur 77.1 egn (M=3) K03809 - Trp repressor binding protein   EC:1.6.5.2 validated
Qrob_P0488670.2 Quercus robur 88.0 egn (M=3) K03809 - Trp repressor binding protein   EC:1.6.5.2 validated

246 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0045892 GO:0000122
is_a GO:0045892 GO:0000183
is_a GO:0045892 GO:0000410
is_a GO:0045892 GO:0000433
is_a GO:0045892 GO:0000434
is_a GO:0045892 GO:0000437
is_a GO:0045892 GO:0001081
is_a GO:0045892 GO:0001198
negatively regulates GO:0045892 GO:0001308
regulates GO:0045892 GO:0001308
is_a GO:0045892 GO:0006342
part of GO:0045892 GO:0006343
part of GO:0045892 GO:0006344
is_a GO:0045892 GO:0006346
is_a GO:0045892 GO:0006348
is_a GO:0045892 GO:0007068
is_a GO:0045892 GO:0007069
is_a GO:0045892 GO:0007070
is_a GO:0045892 GO:0007071
is_a GO:0045892 GO:0010620
is_a GO:0045892 GO:0010621
is_a GO:0045892 GO:0010674
is_a GO:0045892 GO:0010678
is_a GO:0045892 GO:0010688
is_a GO:0045892 GO:0010689
is_a GO:0045892 GO:0010690
is_a GO:0045892 GO:0010691
is_a GO:0045892 GO:0010768
is_a GO:0045892 GO:0010944
regulates GO:0045892 GO:0010964

15 Synonyms

Name Type
down-regulation of transcription, DNA-dependent synonym
down-regulation of gene-specific transcription synonym
downregulation of transcription, DNA-dependent synonym
downregulation of gene-specific transcription synonym
down regulation of transcription, DNA-dependent synonym
GO:0061021 alt_id
down regulation of gene-specific transcription synonym
GO:0016481 alt_id
GO:0032582 alt_id
negative regulation of transcription, DNA-dependent synonym
transcription repressor activity synonym
negative regulation of cellular transcription, DNA-dependent synonym
negative regulation of gene-specific transcription synonym
inhibition of gene-specific transcription synonym
inhibition of transcription, DNA-dependent synonym