GO Term : GO:0033743 peptide-methionine (R)-S-oxide reductase activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the reaction: peptide-L-methionine + H(2)O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.

0 Cross References

1 Ontology

Name
GO

6 Parents

Identifier Name Description
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.
GO:0033743 peptide-methionine (R)-S-oxide reductase activity Catalysis of the reaction: peptide-L-methionine + H(2)O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0016667 oxidoreductase activity, acting on a sulfur group of donors Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.

3 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0014040.2 Quercus robur 99.0 egn (M=2) 1.8.4.12 - Peptide-methionine (R)-S-oxide reductase.   EC:1.8.4.12 validated
Qrob_P0327210.2 Quercus robur     (M=2) 1.8.4.12 - Peptide-methionine (R)-S-oxide reductase. Qrob_P0014670.1 EC:1.8.4.12 manual_v1
Qrob_P0632120.2 Quercus robur 100.0 egn       validated

5 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016671 GO:0033743
is_a GO:0003674 GO:0033743
is_a GO:0003824 GO:0033743
is_a GO:0016491 GO:0033743
is_a GO:0016667 GO:0033743

14 Synonyms

Name Type
methionine S-oxide reductase activity synonym
methionine sulfoxide reductase activity synonym
selenoprotein R synonym
methionine S-oxide reductase (R-form oxidizing) activity synonym
protein-methionine-R-oxide reductase activity synonym
pMSR synonym
pMRsr synonym
PilB synonym
peptide-methionine:thioredoxin-disulfide S-oxidoreductase [methionine (R)-S-oxide-forming] activity synonym
MsrB synonym
methionine sulfoxide reductase B activity synonym
GO:0000318 alt_id
SelX synonym
SelR synonym