GO Term : GO:0004462 lactoylglutathione lyase activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.

0 Cross References

1 Ontology

Name
GO

5 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0004462 lactoylglutathione lyase activity Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.
GO:0016829 lyase activity Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
GO:0016846 carbon-sulfur lyase activity Catalysis of the elimination of hydrogen sulfide or substituted H2S.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

3 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0010040.2 Quercus robur 86.4 egn (M=2) K01759 - lactoylglutathione lyase [EC:4.4.1.5]   EC:4.4.1.5 validated
Qrob_P0264610.2 Quercus robur 93.0 egn (M=2) K01759 - lactoylglutathione lyase [EC:4.4.1.5]   EC:4.4.1.5 validated
Qrob_P0731190.2 Quercus robur 100.0 egn (M=1) PTHR10374:SF2 - GLYOXALASE DOMAIN-CONTAINING PROTEIN 4   EC:4.4.1.5 validated

4 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016846 GO:0004462
is_a GO:0016829 GO:0004462
is_a GO:0003674 GO:0004462
is_a GO:0003824 GO:0004462

7 Synonyms

Name Type
methylglyoxalase activity synonym
ketone-aldehyde mutase activity synonym
glyoxylase I synonym
glyoxalase I activity synonym
aldoketomutase activity synonym
(R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing; glutathione-forming) synonym
(R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing) activity synonym