Protein : Qrob_P0572940.2 Q. robur
Protein Identifier  ? Qrob_P0572940.2 Organism . Name  Quercus robur
Score  97.0 Score Type  egn
Protein Description  (M=2) 3.1.16.1 - Spleen exonuclease. Code Enzyme  EC:3.1.16.1
Gene Prediction Quality  validated Protein length 

Sequence

Length: 614  
Kegg Orthology  K15338
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0006281 DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
GO:0004518 nuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids.

43 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|vvi:100256642 1 585 + 585 Gaps:34 100.00 565 72.21 0.0 flap endonuclease GEN-like 2-like
blastp_kegg lcl|cic:CICLE_v10004614mg 1 613 + 613 Gaps:36 100.00 583 69.98 0.0 hypothetical protein
blastp_kegg lcl|cit:102631209 1 613 + 613 Gaps:36 100.00 583 69.81 0.0 flap endonuclease GEN-like 2-like
blastp_kegg lcl|gmx:100806919 1 612 + 612 Gaps:58 99.82 571 71.75 0.0 flap endonuclease GEN-like 2-like
blastp_kegg lcl|tcc:TCM_015153 1 612 + 612 Gaps:48 99.83 589 69.22 0.0 Single-stranded DNA endonuclease family protein
blastp_kegg lcl|mtr:MTR_6g055360 1 612 + 612 Gaps:60 99.82 571 70.88 0.0 Flap endonuclease GEN-like protein
blastp_kegg lcl|pvu:PHAVU_004G117400g 1 612 + 612 Gaps:61 99.83 574 69.63 0.0 hypothetical protein
blastp_kegg lcl|cam:101502119 1 611 + 611 Gaps:63 99.65 572 70.00 0.0 flap endonuclease GEN-like 2-like
blastp_kegg lcl|sot:102598638 1 608 + 608 Gaps:44 99.33 600 63.59 0.0 flap endonuclease GEN-like 2-like
blastp_kegg lcl|csv:101214962 1 608 + 608 Gaps:54 99.47 563 66.96 0.0 flap endonuclease GEN-like 2-like
blastp_pdb 2izo_A 8 236 + 229 Gaps:25 73.41 346 26.38 3e-19 mol:protein length:346 FLAP STRUCTURE-SPECIFIC ENDONUCLEASE
blastp_pdb 1rxw_A 1 237 + 237 Gaps:26 76.49 336 24.51 2e-15 mol:protein length:336 Flap structure-specific endonuclease
blastp_pdb 1rxv_B 1 237 + 237 Gaps:26 76.49 336 24.51 2e-15 mol:protein length:336 Flap structure-specific endonuclease
blastp_pdb 1rxv_A 1 237 + 237 Gaps:26 76.49 336 24.51 2e-15 mol:protein length:336 Flap structure-specific endonuclease
blastp_pdb 1mc8_B 14 233 + 220 Gaps:25 71.43 343 26.53 5e-15 mol:protein length:343 Flap Endonuclease-1
blastp_pdb 1mc8_A 14 233 + 220 Gaps:25 71.43 343 26.53 5e-15 mol:protein length:343 Flap Endonuclease-1
blastp_pdb 3ory_A 1 236 + 236 Gaps:32 72.18 363 26.34 3e-13 mol:protein length:363 flap endonuclease 1
blastp_pdb 1b43_B 14 233 + 220 Gaps:41 72.06 340 26.53 1e-12 mol:protein length:340 PROTEIN (FEN-1)
blastp_pdb 1b43_A 14 233 + 220 Gaps:41 72.06 340 26.53 1e-12 mol:protein length:340 PROTEIN (FEN-1)
blastp_pdb 3q8l_A 53 239 + 187 Gaps:31 58.06 341 27.78 9e-11 mol:protein length:341 Flap endonuclease 1
blastp_uniprot_sprot sp|Q9M2Z3|GENL2_ARATH 1 612 + 612 Gaps:58 99.67 600 58.03 0.0 Flap endonuclease GEN-like 2 OS Arabidopsis thaliana GN GEN2 PE 2 SV 2
blastp_uniprot_sprot sp|Q8W5R1|GENL2_ORYSJ 1 561 + 561 Gaps:65 78.00 641 60.60 0.0 Flap endonuclease GEN-like 2 OS Oryza sativa subsp. japonica GN SEND1 PE 2 SV 1
blastp_uniprot_sprot sp|Q8BMI4|GEN_MOUSE 1 483 + 483 Gaps:70 53.19 908 30.85 5e-48 Flap endonuclease GEN homolog 1 OS Mus musculus GN Gen1 PE 2 SV 2
blastp_uniprot_sprot sp|Q17RS7|GEN_HUMAN 1 473 + 473 Gaps:69 52.42 908 28.78 1e-43 Flap endonuclease GEN homolog 1 OS Homo sapiens GN GEN1 PE 1 SV 2
blastp_uniprot_sprot sp|Q9ATY5|UVH3_ARATH 1 387 + 387 Gaps:55 25.49 1479 36.07 3e-31 DNA repair protein UVH3 OS Arabidopsis thaliana GN UVH3 PE 2 SV 1
blastp_uniprot_sprot sp|Q9LPD2|GENL1_ARATH 1 248 + 248 Gaps:13 41.24 599 38.87 3e-31 Flap endonuclease GEN-like 1 OS Arabidopsis thaliana GN GEN1 PE 2 SV 3
blastp_uniprot_sprot sp|Q9VRJ0|GEN_DROME 1 216 + 216 Gaps:14 30.85 726 35.71 1e-29 Flap endonuclease GEN OS Drosophila melanogaster GN Gen PE 1 SV 1
blastp_uniprot_sprot sp|Q64MA3|GENL1_ORYSJ 1 248 + 248 Gaps:7 40.54 629 32.55 2e-29 Flap endonuclease GEN-like 1 OS Oryza sativa subsp. japonica GN RAD PE 2 SV 1
blastp_uniprot_sprot sp|Q29FC1|GEN_DROPS 1 216 + 216 Gaps:11 29.58 754 34.53 2e-28 Flap endonuclease GEN OS Drosophila pseudoobscura pseudoobscura GN Gen PE 3 SV 1
blastp_uniprot_sprot sp|P61942|FEN_NANEQ 1 239 + 239 Gaps:24 76.99 339 30.27 1e-26 Flap endonuclease 1 OS Nanoarchaeum equitans (strain Kin4-M) GN fen PE 3 SV 1

25 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
SMART 130 200 71 SM00484 none Xeroderma pigmentosum G I-region IPR006086
PANTHER 285 314 30 PTHR11081 none none IPR006084
Gene3D 1 199 199 G3DSA:3.40.50.1010 none none IPR029060
SMART 202 235 34 SM00279 none Helix-hairpin-helix class 2 (Pol1 family) motifs IPR008918
PANTHER 338 491 154 PTHR11081 none none IPR006084
PANTHER 2 258 257 PTHR11081 none none IPR006084
PRINTS 129 146 18 PR00853 none Xeroderma pigmentosum group G/yeast RAD superfamily signature IPR006084
PRINTS 24 38 15 PR00853 none Xeroderma pigmentosum group G/yeast RAD superfamily signature IPR006084
PRINTS 150 170 21 PR00853 none Xeroderma pigmentosum group G/yeast RAD superfamily signature IPR006084
PRINTS 71 90 20 PR00853 none Xeroderma pigmentosum group G/yeast RAD superfamily signature IPR006084
PRINTS 205 220 16 PR00853 none Xeroderma pigmentosum group G/yeast RAD superfamily signature IPR006084
Pfam 132 215 84 PF00867 none XPG I-region IPR006086
SUPERFAMILY 406 461 56 SSF54160 none none IPR016197
PANTHER 285 314 30 PTHR11081:SF17 none none none
PANTHER 2 258 257 PTHR11081:SF17 none none none
Pfam 1 91 91 PF00752 none XPG N-terminal domain IPR006085
ProSiteProfiles 405 465 61 PS50013 none Chromo and chromo shadow domain profile. IPR000953
Coils 451 472 22 Coil none none none
SUPERFAMILY 2 215 214 SSF88723 none none IPR029060
SMART 1 97 97 SM00485 none Xeroderma pigmentosum G N-region IPR006085
PANTHER 338 491 154 PTHR11081:SF17 none none none
Gene3D 202 242 41 G3DSA:1.10.150.20 none none none
Gene3D 407 466 60 G3DSA:2.40.50.40 none none none
SUPERFAMILY 317 386 70 SSF47807 none none IPR020045
SUPERFAMILY 200 243 44 SSF47807 none none IPR020045

0 Localization

5 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2003_QTL11_peak_Bud_burst_3P Qrob_Chr09 9 s_1CGP2H_273 v_15801_330 27,16 4,16 48,16 lod 2,3 5,1
Bourran2_2004_QTL12_peak_Bud_burst_3P Qrob_Chr09 9 s_1BDO6G_250 s_1A83AM_496 34,31 9,31 44,31 lod 3,6 7,6
Bourran2_2015_nSecLBD_A4 Qrob_Chr09 9 v_15847_485 v_8329_369 35,81 34,88 37,45 lod 4.4 10.4
PM_1999_QTL15_peak_Bud_burst_3P Qrob_Chr09 9 s_1CGP2H_273 v_15801_330 27,16 9,16 47,16 lod 3,6 6,5
Bourran1_2003_QTL5_peak_Bud_burst_3P Qrob_Chr09 9 s_1ATM17_504 s_1AYZFM_899 29,81 19,81 41,81 lod 3,3 8,9

0 Targeting