Protein : Qrob_P0550960.2 Q. robur
Protein Identifier  ? Qrob_P0550960.2 Organism . Name  Quercus robur
Score  76.0 Score Type  egn
Protein Description  (M=1) PTHR10848:SF1 - gb def: meiotic recombination protein rec12 related protein [imported] - neurospora cras Code Enzyme  EC:5.99.1.3
Gene Prediction Quality  validated Protein length 

Sequence

Length: 288  
Kegg Orthology  K10878
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0 Synonyms

6 GO Terms

Identifier Name Description
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0005524 ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0005694 chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
GO:0006259 DNA metabolic process Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
GO:0000737 DNA catabolic process, endonucleolytic The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.

33 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|tcc:TCM_016342 1 287 + 287 Gaps:8 77.23 382 85.08 0.0 Sporulation 11-2
blastp_kegg lcl|cic:CICLE_v10024616mg 2 287 + 286 Gaps:8 76.96 382 85.03 0.0 hypothetical protein
blastp_kegg lcl|pop:POPTR_0001s09890g 1 287 + 287 Gaps:8 89.12 331 84.41 0.0 hypothetical protein
blastp_kegg lcl|pper:PRUPE_ppa024198mg 2 287 + 286 Gaps:8 76.96 382 82.65 6e-180 hypothetical protein
blastp_kegg lcl|pmum:103337572 2 287 + 286 Gaps:8 76.96 382 82.31 1e-178 meiotic recombination protein SPO11-2
blastp_kegg lcl|cit:102613167 2 287 + 286 Gaps:12 77.20 386 81.88 5e-177 meiotic recombination protein SPO11-2-like
blastp_kegg lcl|cam:101490126 1 287 + 287 Gaps:22 77.83 397 77.67 2e-175 meiotic recombination protein SPO11-2-like
blastp_kegg lcl|gmx:100784732 1 287 + 287 Gaps:8 77.23 382 80.34 2e-174 meiotic recombination protein SPO11-2-like
blastp_kegg lcl|mdm:103411708 2 287 + 286 Gaps:8 76.96 382 80.95 3e-174 meiotic recombination protein SPO11-2
blastp_kegg lcl|mtr:MTR_5g009990 1 287 + 287 Gaps:16 77.69 390 78.88 2e-173 Meiotic recombination protein SPO11-2
blastp_pdb 2zbk_G 4 287 + 284 Gaps:37 80.98 389 27.94 1e-28 mol:protein length:389 Type II DNA topoisomerase VI subunit A
blastp_pdb 2zbk_E 4 287 + 284 Gaps:37 80.98 389 27.94 1e-28 mol:protein length:389 Type II DNA topoisomerase VI subunit A
blastp_pdb 2zbk_C 4 287 + 284 Gaps:37 80.98 389 27.94 1e-28 mol:protein length:389 Type II DNA topoisomerase VI subunit A
blastp_pdb 2zbk_A 4 287 + 284 Gaps:37 80.98 389 27.94 1e-28 mol:protein length:389 Type II DNA topoisomerase VI subunit A
blastp_pdb 1d3y_B 4 281 + 278 Gaps:23 96.68 301 30.24 1e-24 mol:protein length:301 DNA TOPOISOMERASE VI A SUBUNIT
blastp_pdb 1d3y_A 4 281 + 278 Gaps:23 96.68 301 30.24 1e-24 mol:protein length:301 DNA TOPOISOMERASE VI A SUBUNIT
blastp_pdb 2q2e_A 23 271 + 249 Gaps:25 69.92 369 25.19 2e-11 mol:protein length:369 Type II DNA topoisomerase VI subunit A
blastp_uniprot_sprot sp|Q9M4A1|SPO12_ARATH 3 287 + 285 Gaps:8 76.50 383 77.82 9e-173 Meiotic recombination protein SPO11-2 OS Arabidopsis thaliana GN SPO11-2 PE 1 SV 1
blastp_uniprot_sprot sp|Q9LZ03|TOP6A_ARATH 14 287 + 274 Gaps:20 65.57 427 35.00 2e-51 DNA topoisomerase 6 subunit A OS Arabidopsis thaliana GN TOP6A PE 1 SV 1
blastp_uniprot_sprot sp|A2XFC1|TOP6A_ORYSI 3 287 + 285 Gaps:21 65.61 442 36.55 7e-50 DNA topoisomerase 6 subunit A OS Oryza sativa subsp. indica GN TOP6A PE 2 SV 2
blastp_uniprot_sprot sp|Q9Y5K1|SPO11_HUMAN 5 287 + 283 Gaps:23 73.23 396 33.45 1e-46 Meiotic recombination protein SPO11 OS Homo sapiens GN SPO11 PE 2 SV 1
blastp_uniprot_sprot sp|Q9WTK8|SPO11_MOUSE 5 287 + 283 Gaps:23 73.23 396 32.07 4e-43 Meiotic recombination protein SPO11 OS Mus musculus GN Spo11 PE 2 SV 2
blastp_uniprot_sprot sp|Q9M4A2|SPO11_ARATH 14 281 + 268 Gaps:23 75.97 362 32.73 1e-35 Meiotic recombination protein SPO11-1 OS Arabidopsis thaliana GN SPO11-1 PE 1 SV 1
blastp_uniprot_sprot sp|P40384|REC12_SCHPO 11 265 + 255 Gaps:27 72.46 345 29.60 4e-30 Meiotic recombination protein rec12 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN rec12 PE 1 SV 2
blastp_uniprot_sprot sp|O05208|TOP6A_SULSH 4 287 + 284 Gaps:37 80.98 389 27.94 5e-28 Type 2 DNA topoisomerase 6 subunit A OS Sulfolobus shibatae GN top6A PE 1 SV 1
blastp_uniprot_sprot sp|Q971T1|TOP6A_SULTO 4 287 + 284 Gaps:35 80.88 387 25.56 1e-25 Type 2 DNA topoisomerase 6 subunit A OS Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) GN top6A PE 3 SV 1
blastp_uniprot_sprot sp|A2BLE8|TOP6A_HYPBU 4 287 + 284 Gaps:35 80.88 387 25.88 6e-24 Type 2 DNA topoisomerase 6 subunit A OS Hyperthermus butylicus (strain DSM 5456 / JCM 9403) GN top6A PE 3 SV 1
rpsblast_cdd gnl|CDD|177691 1 287 + 287 Gaps:8 76.82 384 76.27 1e-151 PLN00060 PLN00060 meiotic recombination protein SPO11-2 Provisional.
rpsblast_cdd gnl|CDD|173774 115 272 + 158 Gaps:4 100.00 160 43.12 9e-46 cd00223 TOPRIM_TopoIIB_SPO TOPRIM_TopoIIB_SPO: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in the type IIB family of DNA topoisomerases and Spo11. This subgroup contains proteins similar to Sulfolobus shibatae topoisomerase VI (TopoVI) and Saccharomyces cerevisiae meiotic recombination factor: Spo11. Type II DNA topoisomerases catalyze the ATP-dependent transport of one DNA duplex through another in the process generating transient double strand breaks via covalent attachments to both DNA strands at the 5' positions. TopoVI enzymes are heterotetramers found in archaea and plants. Spo11 plays a role in generating the double strand breaks that initiate homologous recombination during meiosis. S. shibatae TopoVI relaxes both positive and negative supercoils and in addition has a strong decatenase activity. The TOPRIM domain has two conserved motifs one of which centers at a conserved glutamate and the other one at two conserved aspartates (DxD. For topoisomerases the conserved glutamate is believed to act as a general base in strand joining and as a general acid in strand cleavage. The DXD motif may co-ordinate Mg2+ a cofactor required for full catalytic function.
rpsblast_cdd gnl|CDD|31883 4 281 + 278 Gaps:14 80.34 356 31.82 1e-41 COG1697 COG1697 DNA topoisomerase VI subunit A [DNA replication recombination and repair].

11 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
SUPERFAMILY 7 287 281 SSF56726 none none IPR002815
Pfam 3 73 71 PF04406 none Type IIB DNA topoisomerase IPR013049
Gene3D 4 75 72 G3DSA:1.10.10.10 none none IPR011991
PANTHER 2 287 286 PTHR10848:SF1 none none none
PRINTS 174 190 17 PR01550 none DNA topoisomerase VI subunit A family signature IPR002815
PRINTS 49 66 18 PR01550 none DNA topoisomerase VI subunit A family signature IPR002815
PRINTS 117 134 18 PR01550 none DNA topoisomerase VI subunit A family signature IPR002815
PRINTS 141 162 22 PR01550 none DNA topoisomerase VI subunit A family signature IPR002815
PRINTS 67 82 16 PR01550 none DNA topoisomerase VI subunit A family signature IPR002815
PANTHER 2 287 286 PTHR10848 none none IPR002815
Gene3D 81 287 207 G3DSA:3.40.1360.10 none none none

0 Localization

0 Qtllist

0 Targeting