5 GO Terms
Identifier | Name | Description |
---|---|---|
GO:0003677 | DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
GO:0003824 | catalytic activity | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
GO:0006281 | DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. |
GO:0004518 | nuclease activity | Catalysis of the hydrolysis of ester linkages within nucleic acids. |
GO:0016788 | hydrolase activity, acting on ester bonds | Catalysis of the hydrolysis of any ester bond. |
43 Blast
Analysis | Hit | Start | End | Strand | Length | Note | Hit Coverage | Hit Length | Hit Pident | E Val | Hit Description |
---|---|---|---|---|---|---|---|---|---|---|---|
blastp_kegg | lcl|pmum:103325046 | 1 | 738 | + | 738 | Gaps:75 | 99.13 | 693 | 69.87 | 0.0 | exonuclease 1 |
blastp_kegg | lcl|cit:102615179 | 1 | 738 | + | 738 | Gaps:68 | 99.86 | 691 | 68.26 | 0.0 | exonuclease 1-like |
blastp_kegg | lcl|tcc:TCM_029587 | 1 | 726 | + | 726 | Gaps:72 | 99.70 | 674 | 68.60 | 0.0 | 5'-3' exonuclease family protein isoform 1 |
blastp_kegg | lcl|gmx:100798062 | 1 | 732 | + | 732 | Gaps:60 | 99.06 | 743 | 62.91 | 0.0 | exonuclease 1-like |
blastp_kegg | lcl|mdm:103422350 | 1 | 738 | + | 738 | Gaps:80 | 99.28 | 691 | 67.06 | 0.0 | exonuclease 1-like |
blastp_kegg | lcl|pxb:103951219 | 1 | 738 | + | 738 | Gaps:81 | 99.13 | 691 | 67.30 | 0.0 | exonuclease 1 |
blastp_kegg | lcl|vvi:100245156 | 1 | 738 | + | 738 | Gaps:94 | 99.09 | 658 | 68.25 | 0.0 | exonuclease 1-like |
blastp_kegg | lcl|cam:101511143 | 1 | 733 | + | 733 | Gaps:69 | 95.98 | 721 | 64.31 | 0.0 | exonuclease 1-like |
blastp_kegg | lcl|cic:CICLE_v10014561mg | 1 | 712 | + | 712 | Gaps:84 | 100.00 | 646 | 68.42 | 0.0 | hypothetical protein |
blastp_kegg | lcl|csv:101214177 | 1 | 739 | + | 739 | Gaps:82 | 99.71 | 685 | 63.98 | 0.0 | exonuclease 1-like |
blastp_pdb | 3qeb_Z | 1 | 311 | + | 311 | Gaps:7 | 89.77 | 352 | 41.77 | 2e-73 | mol:protein length:352 Exonuclease 1 |
blastp_pdb | 3qea_Z | 1 | 311 | + | 311 | Gaps:7 | 89.77 | 352 | 41.77 | 2e-73 | mol:protein length:352 Exonuclease 1 |
blastp_pdb | 3qe9_Z | 1 | 311 | + | 311 | Gaps:7 | 89.77 | 352 | 41.46 | 2e-72 | mol:protein length:352 Exonuclease 1 |
blastp_pdb | 3qe9_Y | 1 | 311 | + | 311 | Gaps:7 | 89.77 | 352 | 41.46 | 2e-72 | mol:protein length:352 Exonuclease 1 |
blastp_pdb | 1ul1_Z | 2 | 286 | + | 285 | Gaps:13 | 76.52 | 379 | 26.21 | 5e-19 | mol:protein length:379 Flap endonuclease-1 |
blastp_pdb | 1ul1_Y | 2 | 286 | + | 285 | Gaps:13 | 76.52 | 379 | 26.21 | 5e-19 | mol:protein length:379 Flap endonuclease-1 |
blastp_pdb | 1ul1_X | 2 | 286 | + | 285 | Gaps:13 | 76.52 | 379 | 26.21 | 5e-19 | mol:protein length:379 Flap endonuclease-1 |
blastp_pdb | 3q8l_A | 2 | 286 | + | 285 | Gaps:13 | 85.04 | 341 | 26.21 | 8e-19 | mol:protein length:341 Flap endonuclease 1 |
blastp_pdb | 3q8k_A | 2 | 286 | + | 285 | Gaps:13 | 85.04 | 341 | 26.21 | 8e-19 | mol:protein length:341 Flap endonuclease 1 |
blastp_pdb | 3q8m_B | 2 | 286 | + | 285 | Gaps:13 | 85.04 | 341 | 25.86 | 8e-18 | mol:protein length:341 Flap endonuclease 1 |
blastp_uniprot_sprot | sp|Q8L6Z7|EXO1_ARATH | 1 | 738 | + | 738 | Gaps:80 | 99.86 | 735 | 56.40 | 0.0 | Exonuclease 1 OS Arabidopsis thaliana GN EXO1 PE 2 SV 2 |
blastp_uniprot_sprot | sp|Q60GC1|EXO1_ORYSJ | 1 | 737 | + | 737 | Gaps:66 | 86.24 | 836 | 51.46 | 0.0 | Exonuclease 1 OS Oryza sativa subsp. japonica GN EXO1 PE 2 SV 1 |
blastp_uniprot_sprot | sp|Q54ED2|EXO1_DICDI | 1 | 294 | + | 294 | Gaps:2 | 28.30 | 1046 | 46.62 | 6e-81 | Exonuclease 1 OS Dictyostelium discoideum GN exo1 PE 3 SV 1 |
blastp_uniprot_sprot | sp|Q803U7|EXO1_DANRE | 1 | 301 | + | 301 | Gaps:6 | 37.84 | 806 | 47.21 | 3e-77 | Exonuclease 1 OS Danio rerio GN exo1 PE 2 SV 1 |
blastp_uniprot_sprot | sp|Q9W6K2|EXO1_XENLA | 1 | 364 | + | 364 | Gaps:17 | 48.91 | 734 | 40.67 | 2e-76 | Exonuclease 1 OS Xenopus laevis GN exo1 PE 2 SV 1 |
blastp_uniprot_sprot | sp|Q9UQ84|EXO1_HUMAN | 1 | 352 | + | 352 | Gaps:18 | 42.79 | 846 | 40.33 | 3e-71 | Exonuclease 1 OS Homo sapiens GN EXO1 PE 1 SV 2 |
blastp_uniprot_sprot | sp|Q9QZ11|EXO1_MOUSE | 1 | 311 | + | 311 | Gaps:7 | 37.75 | 837 | 42.09 | 3e-69 | Exonuclease 1 OS Mus musculus GN Exo1 PE 2 SV 2 |
blastp_uniprot_sprot | sp|P53695|EXO1_SCHPO | 1 | 342 | + | 342 | Gaps:6 | 59.54 | 571 | 35.88 | 2e-66 | Exodeoxyribonuclease 1 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN exo1 PE 1 SV 1 |
blastp_uniprot_sprot | sp|P39875|EXO1_YEAST | 1 | 297 | + | 297 | Gaps:2 | 42.59 | 702 | 38.80 | 1e-64 | Exodeoxyribonuclease 1 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN EXO1 PE 1 SV 2 |
blastp_uniprot_sprot | sp|Q24558|EXO1_DROME | 1 | 332 | + | 332 | Gaps:6 | 46.17 | 732 | 37.87 | 2e-62 | Exonuclease 1 OS Drosophila melanogaster GN tos PE 1 SV 1 |
17 Domain Motifs
Analysis | Begin | End | Length | Domain Identifier | Cross Ref | Description | Inter Pro |
---|---|---|---|---|---|---|---|
SMART | 213 | 246 | 34 | SM00279 | none | Helix-hairpin-helix class 2 (Pol1 family) motifs | IPR008918 |
Pfam | 139 | 226 | 88 | PF00867 | none | XPG I-region | IPR006086 |
SMART | 138 | 208 | 71 | SM00484 | none | Xeroderma pigmentosum G I-region | IPR006086 |
PANTHER | 2 | 408 | 407 | PTHR11081:SF8 | none | none | none |
Pfam | 1 | 98 | 98 | PF00752 | none | XPG N-terminal domain | IPR006085 |
ProSitePatterns | 71 | 85 | 15 | PS00841 | none | XPG protein signature 1. | IPR019974 |
Gene3D | 1 | 195 | 195 | G3DSA:3.40.50.1010 | none | none | IPR029060 |
PRINTS | 24 | 38 | 15 | PR00853 | none | Xeroderma pigmentosum group G/yeast RAD superfamily signature | IPR006084 |
PRINTS | 137 | 154 | 18 | PR00853 | none | Xeroderma pigmentosum group G/yeast RAD superfamily signature | IPR006084 |
PRINTS | 216 | 231 | 16 | PR00853 | none | Xeroderma pigmentosum group G/yeast RAD superfamily signature | IPR006084 |
PRINTS | 73 | 92 | 20 | PR00853 | none | Xeroderma pigmentosum group G/yeast RAD superfamily signature | IPR006084 |
PRINTS | 158 | 178 | 21 | PR00853 | none | Xeroderma pigmentosum group G/yeast RAD superfamily signature | IPR006084 |
SUPERFAMILY | 211 | 336 | 126 | SSF47807 | none | none | IPR020045 |
SUPERFAMILY | 2 | 226 | 225 | SSF88723 | none | none | IPR029060 |
PANTHER | 2 | 408 | 407 | PTHR11081 | none | none | IPR006084 |
Gene3D | 212 | 257 | 46 | G3DSA:1.10.150.20 | none | none | none |
SMART | 1 | 99 | 99 | SM00485 | none | Xeroderma pigmentosum G N-region | IPR006085 |