Protein : Qrob_P0447880.2 Q. robur
Protein Identifier  ? Qrob_P0447880.2 Organism . Name  Quercus robur
Score  0.0 Score Type  egn
Protein Description  (M=9) K10878 - meiotic recombination protein SPO11 Code Enzyme  EC:5.99.1.3
Gene Prediction Quality  validated Protein length 

Sequence

Length: 196  
Kegg Orthology  K10878
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0005694 chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
GO:0000737 DNA catabolic process, endonucleolytic The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.

32 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|gmx:100813920 1 193 + 193 Gaps:23 58.86 367 69.44 3e-102 meiotic recombination protein SPO11-1-like
blastp_kegg lcl|pop:POPTR_0001s37540g 1 189 + 189 Gaps:23 58.08 365 72.17 6e-102 POPTRDRAFT_550198 DNA topoisomerase VIA family protein
blastp_kegg lcl|fve:101293370 1 195 + 195 Gaps:23 59.73 365 67.89 3e-100 meiotic recombination protein SPO11-1-like
blastp_kegg lcl|pmum:103342724 1 195 + 195 Gaps:23 59.73 365 68.81 4e-99 meiotic recombination protein SPO11-1
blastp_kegg lcl|vvi:100256655 1 190 + 190 Gaps:23 59.00 361 70.89 9e-99 meiotic recombination protein SPO11-1-like
blastp_kegg lcl|pxb:103941907 1 195 + 195 Gaps:24 59.84 366 68.04 3e-97 meiotic recombination protein SPO11-1-like
blastp_kegg lcl|pxb:103965437 1 195 + 195 Gaps:24 59.84 366 68.04 3e-97 meiotic recombination protein SPO11-1-like
blastp_kegg lcl|mdm:103448311 1 195 + 195 Gaps:23 59.73 365 68.35 4e-97 meiotic recombination protein SPO11-1
blastp_kegg lcl|pper:PRUPE_ppa006320mg 1 195 + 195 Gaps:23 52.28 417 68.35 6e-97 hypothetical protein
blastp_kegg lcl|tcc:TCM_030659 1 182 + 182 Gaps:23 42.36 484 71.71 1e-96 Spo11/DNA topoisomerase VI
blastp_pdb 2zbk_G 1 195 + 195 Gaps:44 57.84 389 31.56 6e-21 mol:protein length:389 Type II DNA topoisomerase VI subunit A
blastp_pdb 2zbk_E 1 195 + 195 Gaps:44 57.84 389 31.56 6e-21 mol:protein length:389 Type II DNA topoisomerase VI subunit A
blastp_pdb 2zbk_C 1 195 + 195 Gaps:44 57.84 389 31.56 6e-21 mol:protein length:389 Type II DNA topoisomerase VI subunit A
blastp_pdb 2zbk_A 1 195 + 195 Gaps:44 57.84 389 31.56 6e-21 mol:protein length:389 Type II DNA topoisomerase VI subunit A
blastp_pdb 1d3y_B 8 190 + 183 Gaps:28 67.44 301 29.06 2e-17 mol:protein length:301 DNA TOPOISOMERASE VI A SUBUNIT
blastp_pdb 1d3y_A 8 190 + 183 Gaps:28 67.44 301 29.06 2e-17 mol:protein length:301 DNA TOPOISOMERASE VI A SUBUNIT
blastp_pdb 2q2e_A 22 190 + 169 Gaps:28 50.68 369 22.46 9e-08 mol:protein length:369 Type II DNA topoisomerase VI subunit A
blastp_uniprot_sprot sp|Q9M4A2|SPO11_ARATH 1 193 + 193 Gaps:23 59.67 362 64.35 2e-93 Meiotic recombination protein SPO11-1 OS Arabidopsis thaliana GN SPO11-1 PE 1 SV 1
blastp_uniprot_sprot sp|Q9LZ03|TOP6A_ARATH 1 190 + 190 Gaps:24 49.65 427 36.79 1e-36 DNA topoisomerase 6 subunit A OS Arabidopsis thaliana GN TOP6A PE 1 SV 1
blastp_uniprot_sprot sp|Q9Y5K1|SPO11_HUMAN 2 192 + 191 Gaps:27 54.04 396 35.05 1e-35 Meiotic recombination protein SPO11 OS Homo sapiens GN SPO11 PE 2 SV 1
blastp_uniprot_sprot sp|Q9WTK8|SPO11_MOUSE 2 192 + 191 Gaps:27 54.04 396 33.18 4e-35 Meiotic recombination protein SPO11 OS Mus musculus GN Spo11 PE 2 SV 2
blastp_uniprot_sprot sp|A2XFC1|TOP6A_ORYSI 1 190 + 190 Gaps:24 47.96 442 35.38 2e-33 DNA topoisomerase 6 subunit A OS Oryza sativa subsp. indica GN TOP6A PE 2 SV 2
blastp_uniprot_sprot sp|A2BLE8|TOP6A_HYPBU 1 192 + 192 Gaps:48 57.36 387 31.53 1e-20 Type 2 DNA topoisomerase 6 subunit A OS Hyperthermus butylicus (strain DSM 5456 / JCM 9403) GN top6A PE 3 SV 1
blastp_uniprot_sprot sp|O05208|TOP6A_SULSH 1 195 + 195 Gaps:44 57.84 389 31.56 2e-20 Type 2 DNA topoisomerase 6 subunit A OS Sulfolobus shibatae GN top6A PE 1 SV 1
blastp_uniprot_sprot sp|Q9YE67|TOP6A_AERPE 1 192 + 192 Gaps:47 57.33 389 29.60 4e-19 Type 2 DNA topoisomerase 6 subunit A OS Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) GN top6A PE 3 SV 2
blastp_uniprot_sprot sp|Q971T1|TOP6A_SULTO 34 195 + 162 Gaps:35 49.87 387 30.57 3e-18 Type 2 DNA topoisomerase 6 subunit A OS Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) GN top6A PE 3 SV 1
blastp_uniprot_sprot sp|Q9M4A1|SPO12_ARATH 39 195 + 157 Gaps:25 45.43 383 32.76 7e-17 Meiotic recombination protein SPO11-2 OS Arabidopsis thaliana GN SPO11-2 PE 1 SV 1
rpsblast_cdd gnl|CDD|173774 40 179 + 140 Gaps:26 100.00 160 41.88 3e-38 cd00223 TOPRIM_TopoIIB_SPO TOPRIM_TopoIIB_SPO: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in the type IIB family of DNA topoisomerases and Spo11. This subgroup contains proteins similar to Sulfolobus shibatae topoisomerase VI (TopoVI) and Saccharomyces cerevisiae meiotic recombination factor: Spo11. Type II DNA topoisomerases catalyze the ATP-dependent transport of one DNA duplex through another in the process generating transient double strand breaks via covalent attachments to both DNA strands at the 5' positions. TopoVI enzymes are heterotetramers found in archaea and plants. Spo11 plays a role in generating the double strand breaks that initiate homologous recombination during meiosis. S. shibatae TopoVI relaxes both positive and negative supercoils and in addition has a strong decatenase activity. The TOPRIM domain has two conserved motifs one of which centers at a conserved glutamate and the other one at two conserved aspartates (DxD. For topoisomerases the conserved glutamate is believed to act as a general base in strand joining and as a general acid in strand cleavage. The DXD motif may co-ordinate Mg2+ a cofactor required for full catalytic function.
rpsblast_cdd gnl|CDD|179833 1 192 + 192 Gaps:32 57.77 367 30.66 2e-33 PRK04342 PRK04342 DNA topoisomerase VI subunit A Provisional.
rpsblast_cdd gnl|CDD|31883 1 189 + 189 Gaps:28 58.71 356 31.58 7e-27 COG1697 COG1697 DNA topoisomerase VI subunit A [DNA replication recombination and repair].

6 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 1 191 191 G3DSA:3.40.1360.10 none none none
PANTHER 1 195 195 PTHR10848 none none IPR002815
SUPERFAMILY 2 191 190 SSF56726 none none IPR002815
PRINTS 124 148 25 PR01551 none SPO11 homologue signature IPR013048
PRINTS 89 108 20 PR01551 none SPO11 homologue signature IPR013048
PANTHER 1 195 195 PTHR10848:SF3 none none none

0 Localization

8 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran2_2014_nLBD*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,25 0 35,55 lod 2,5951 6
Bourran2_2014_nP*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,19 0 31,97 lod 2,8472 6
Bourran2_2014_nPriLBD_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,36 0 30,43 lod 2,5806 5,1
Champenoux_2015_nSeqBC_A4 Qrob_Chr08 8 v_AD7YD13_501 s_1A7IED_780 43,44 43,42 43,99 lod 3.7 8.9
Bourran2_2014_nEpis*_3P Qrob_Chr08 8 s_1DA4QW_688 s_1DNI7D_820 17,96 0 37,75 lod 2,9745 7,5
Bourran2_2014_nPriBD_3P Qrob_Chr11 11 v_11486_194 s_1AT3E_2335 5,54 0,4 20,6 lod 2,6345 5,9

0 Targeting