Protein : Qrob_P0234940.2 Q. robur
Protein Identifier  ? Qrob_P0234940.2 Organism . Name  Quercus robur
Score  94.1 Score Type  egn
Protein Description  (M=3) K00026 - malate dehydrogenase [EC:1.1.1.37] Code Enzyme  EC:1.1.1.37
Gene Prediction Quality  validated Protein length 

Sequence

Length: 385  
Kegg Orthology  K00026
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0 Synonyms

9 GO Terms

Identifier Name Description
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0005975 carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
GO:0006108 malate metabolic process The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
GO:0030060 L-malate dehydrogenase activity Catalysis of the reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+.
GO:0016615 malate dehydrogenase activity Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate.
GO:0019752 carboxylic acid metabolic process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).

43 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|vvi:100260994 5 384 + 380 Gaps:27 99.16 356 88.39 0.0 malate dehydrogenase glyoxysomal-like
blastp_kegg lcl|fve:101302203 1 384 + 384 Gaps:27 100.00 357 87.11 0.0 malate dehydrogenase glyoxysomal-like
blastp_kegg lcl|vvi:100232924 5 384 + 380 Gaps:27 99.16 356 86.69 0.0 MDHG NAD-malate dehydrogenase
blastp_kegg lcl|cit:102622394 4 384 + 381 Gaps:27 99.44 356 86.72 0.0 malate dehydrogenase glyoxysomal-like
blastp_kegg lcl|pxb:103964654 7 384 + 378 Gaps:27 97.50 360 86.32 0.0 malate dehydrogenase glyoxysomal-like
blastp_kegg lcl|rcu:RCOM_1381350 5 384 + 380 Gaps:27 99.16 356 85.84 0.0 malate dehydrogenase putative (EC:1.1.1.37)
blastp_kegg lcl|sly:101249428 10 384 + 375 Gaps:28 98.58 352 87.32 0.0 malate dehydrogenase glyoxysomal-like
blastp_kegg lcl|cmo:103484892 7 383 + 377 Gaps:27 98.31 356 86.86 0.0 malate dehydrogenase glyoxysomal
blastp_kegg lcl|csv:101225691 7 383 + 377 Gaps:27 98.31 356 86.57 0.0 malate dehydrogenase glyoxysomal-like
blastp_kegg lcl|csv:101219252 7 383 + 377 Gaps:27 98.31 356 86.57 0.0 malate dehydrogenase glyoxysomal-like
blastp_pdb 1sev_B 7 383 + 377 Gaps:27 96.69 362 86.57 0.0 mol:protein length:362 Malate dehydrogenase glyoxysomal precursor
blastp_pdb 1sev_A 7 383 + 377 Gaps:27 96.69 362 86.57 0.0 mol:protein length:362 Malate dehydrogenase glyoxysomal precursor
blastp_pdb 1smk_H 39 383 + 345 Gaps:26 97.85 326 89.03 0.0 mol:protein length:326 Malate dehydrogenase glyoxysomal
blastp_pdb 1smk_G 39 383 + 345 Gaps:26 97.85 326 89.03 0.0 mol:protein length:326 Malate dehydrogenase glyoxysomal
blastp_pdb 1smk_F 39 383 + 345 Gaps:26 97.85 326 89.03 0.0 mol:protein length:326 Malate dehydrogenase glyoxysomal
blastp_pdb 1smk_E 39 383 + 345 Gaps:26 97.85 326 89.03 0.0 mol:protein length:326 Malate dehydrogenase glyoxysomal
blastp_pdb 1smk_D 39 383 + 345 Gaps:26 97.85 326 89.03 0.0 mol:protein length:326 Malate dehydrogenase glyoxysomal
blastp_pdb 1smk_C 39 383 + 345 Gaps:26 97.85 326 89.03 0.0 mol:protein length:326 Malate dehydrogenase glyoxysomal
blastp_pdb 1smk_B 39 383 + 345 Gaps:26 97.85 326 89.03 0.0 mol:protein length:326 Malate dehydrogenase glyoxysomal
blastp_pdb 1smk_A 39 383 + 345 Gaps:26 97.85 326 89.03 0.0 mol:protein length:326 Malate dehydrogenase glyoxysomal
blastp_uniprot_sprot sp|P19446|MDHG_CITLA 7 383 + 377 Gaps:27 98.31 356 86.57 0.0 Malate dehydrogenase glyoxysomal OS Citrullus lanatus PE 1 SV 1
blastp_uniprot_sprot sp|P46488|MDHG_CUCSA 7 383 + 377 Gaps:27 98.31 356 86.57 0.0 Malate dehydrogenase glyoxysomal OS Cucumis sativus GN MDHG PE 2 SV 1
blastp_uniprot_sprot sp|Q42972|MDHG_ORYSJ 12 384 + 373 Gaps:27 97.19 356 85.55 0.0 Malate dehydrogenase glyoxysomal OS Oryza sativa subsp. japonica GN Os12g0632700 PE 1 SV 3
blastp_uniprot_sprot sp|P37228|MDHG_SOYBN 1 384 + 384 Gaps:31 100.00 353 83.57 0.0 Malate dehydrogenase glyoxysomal OS Glycine max PE 2 SV 2
blastp_uniprot_sprot sp|O82399|MDHG2_ARATH 7 384 + 378 Gaps:29 99.72 354 83.85 0.0 Probable malate dehydrogenase glyoxysomal OS Arabidopsis thaliana GN At2g22780 PE 2 SV 1
blastp_uniprot_sprot sp|Q9ZP05|MDHG1_ARATH 7 384 + 378 Gaps:31 98.59 354 84.24 0.0 Malate dehydrogenase glyoxysomal OS Arabidopsis thaliana GN At5g09660 PE 2 SV 1
blastp_uniprot_sprot sp|Q9XFW3|MDHG2_BRANA 7 384 + 378 Gaps:27 98.60 358 83.00 0.0 Malate dehydrogenase 2 glyoxysomal OS Brassica napus GN MDH2 PE 3 SV 1
blastp_uniprot_sprot sp|Q43743|MDHG1_BRANA 7 384 + 378 Gaps:27 98.60 358 82.44 0.0 Malate dehydrogenase 1 glyoxysomal OS Brassica napus GN MDH1 PE 2 SV 2
blastp_uniprot_sprot sp|P17783|MDHM_CITLA 45 381 + 337 Gaps:26 89.63 347 67.52 3e-142 Malate dehydrogenase mitochondrial OS Citrullus lanatus GN MMDH PE 1 SV 1
blastp_uniprot_sprot sp|Q9ZP06|MDHM1_ARATH 40 384 + 345 Gaps:26 93.55 341 65.20 2e-141 Malate dehydrogenase 1 mitochondrial OS Arabidopsis thaliana GN At1g53240 PE 1 SV 1

12 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
SUPERFAMILY 47 190 144 SSF51735 none none none
SUPERFAMILY 191 336 146 SSF56327 none none IPR015955
TIGRFAM 48 337 290 TIGR01772 "KEGG:00020+1.1.1.37","KEGG:00270+1.1.1.37","KEGG:00620+1.1.1.37","KEGG:00630+1.1.1.37","KEGG:00680+1.1.1.37","KEGG:00710+1.1.1.37","KEGG:00720+1.1.1.37","MetaCyc:PWY-1622","MetaCyc:PWY-5392","MetaCyc:PWY-561","MetaCyc:PWY-5690","MetaCyc:PWY-5913","MetaCyc:PWY-6728","MetaCyc:PWY-6969","MetaCyc:PWY-7115","MetaCyc:PWY-7383" MDH_euk_gproteo: malate dehydrogenase, NAD-dependent IPR010097
Gene3D 192 336 145 G3DSA:3.90.110.10 none none IPR015955
PANTHER 18 336 319 PTHR11540:SF9 none none none
PANTHER 363 384 22 PTHR11540:SF9 none none none
Gene3D 48 191 144 G3DSA:3.40.50.720 none none IPR016040
PANTHER 363 384 22 PTHR11540 none none IPR001557
PANTHER 18 336 319 PTHR11540 none none IPR001557
Pfam 192 336 145 PF02866 none lactate/malate dehydrogenase, alpha/beta C-terminal domain IPR022383
ProSitePatterns 191 203 13 PS00068 "KEGG:00020+1.1.1.37","KEGG:00270+1.1.1.37","KEGG:00620+1.1.1.37","KEGG:00630+1.1.1.37","KEGG:00680+1.1.1.37","KEGG:00710+1.1.1.37","KEGG:00720+1.1.1.37","MetaCyc:PWY-1622","MetaCyc:PWY-5392","MetaCyc:PWY-561","MetaCyc:PWY-5690","MetaCyc:PWY-5913","MetaCyc:PWY-6728","MetaCyc:PWY-6969","MetaCyc:PWY-7115","MetaCyc:PWY-7383","Reactome:REACT_474" Malate dehydrogenase active site signature. IPR001252
Pfam 48 190 143 PF00056 none lactate/malate dehydrogenase, NAD binding domain IPR001236

0 Localization

7 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nEpis*_3P Qrob_Chr08 8 s_1DA4QW_688 s_1DNI7D_820 17,96 0 37,75 lod 2,9745 7,5
Bourran2_2014_nEpis*_A4 Qrob_Chr07 7 v_12400_446 s_1BPEBU_1211 6,93 0 15,13 lod 4,7411 11
Bourran2_2014_nLBD_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 37,41 9,8 50,1 lod 1,9524 4,1
Bourran2_2014_nPriBD_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 34,51 3,36 51,86 lod 1,6747 3,9
Bourran2_2014_nSecLBD_A4 Qrob_Chr07 7 v_8327_222 s_1A4WGY_363 16,04 0 44,69 lod 2,6373 6,5
Bourran2_2014_vEpiBC_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 37,55 14,41 50,01 lod 1,7882 4,8
Champenoux_2015_nEpis_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 26,53 25,47 27,72 lod 4.4 8.9

0 Targeting