Protein : Qrob_P0200840.2 Q. robur
Protein Identifier  ? Qrob_P0200840.2 Organism . Name  Quercus robur
Score  75.0 Score Type  egn
Protein Description  (M=1) K10772 - AP endonuclease 2 [EC:4.2.99.18] Code Enzyme  EC:4.2.99.18
Gene Prediction Quality  validated Protein length 

Sequence

Length: 674  
Kegg Orthology  K10772
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0 Synonyms

6 GO Terms

Identifier Name Description
GO:0008270 zinc ion binding Interacting selectively and non-covalently with zinc (Zn) ions.
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0006281 DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
GO:0004518 nuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids.
GO:0004519 endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.

41 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pmum:103340209 1 673 + 673 Gaps:80 100.00 607 58.81 0.0 DNA-(apurinic or apyrimidinic site) lyase 2
blastp_kegg lcl|mdm:103456392 1 673 + 673 Gaps:84 100.00 605 57.52 0.0 DNA-(apurinic or apyrimidinic site) lyase 2
blastp_kegg lcl|vvi:100264349 1 673 + 673 Gaps:8 82.72 625 63.64 4e-128 DNA-(apurinic or apyrimidinic site) lyase 2-like
blastp_kegg lcl|pper:PRUPE_ppa024373mg 1 673 + 673 Gaps:10 76.61 607 68.39 5e-127 hypothetical protein
blastp_kegg lcl|tcc:TCM_000203 1 673 + 673 Gaps:6 81.33 616 64.07 2e-125 Endonuclease/exonuclease/phosphatase family protein
blastp_kegg lcl|cit:102619750 1 673 + 673 Gaps:19 81.33 632 62.84 4e-124 DNA-(apurinic or apyrimidinic site) lyase 2-like
blastp_kegg lcl|cic:CICLE_v10025146mg 1 673 + 673 Gaps:19 80.38 632 63.19 7e-124 hypothetical protein
blastp_kegg lcl|csv:101222374 1 673 + 673 Gaps:22 81.01 611 64.24 2e-123 DNA-(apurinic or apyrimidinic site) lyase 2-like
blastp_kegg lcl|mtr:MTR_8g075810 1 673 + 673 Gaps:10 74.06 613 65.20 5e-123 DNA-(apurinic or apyrimidinic site) lyase
blastp_kegg lcl|pxb:103967814 1 673 + 673 Gaps:26 81.05 607 65.85 2e-122 DNA-(apurinic or apyrimidinic site) lyase 2-like
blastp_pdb 3g4t_B 1 199 + 199 Gaps:42 59.25 265 36.94 2e-16 mol:protein length:265 Exodeoxyribonuclease
blastp_pdb 3g4t_A 1 199 + 199 Gaps:42 59.25 265 36.94 2e-16 mol:protein length:265 Exodeoxyribonuclease
blastp_pdb 3g3y_B 1 199 + 199 Gaps:42 59.25 265 36.94 2e-16 mol:protein length:265 Exodeoxyribonuclease
blastp_pdb 3g3y_A 1 199 + 199 Gaps:42 59.25 265 36.94 2e-16 mol:protein length:265 Exodeoxyribonuclease
blastp_pdb 3g3c_B 1 199 + 199 Gaps:42 59.25 265 36.94 2e-16 mol:protein length:265 Exodeoxyribonuclease
blastp_pdb 3g3c_A 1 199 + 199 Gaps:42 59.25 265 36.94 2e-16 mol:protein length:265 Exodeoxyribonuclease
blastp_pdb 3g2c_B 1 199 + 199 Gaps:42 59.25 265 36.94 2e-16 mol:protein length:265 Exodeoxyribonuclease
blastp_pdb 3g2c_A 1 199 + 199 Gaps:42 59.25 265 36.94 2e-16 mol:protein length:265 Exodeoxyribonuclease
blastp_pdb 3g1k_B 1 199 + 199 Gaps:42 59.25 265 36.94 2e-16 mol:protein length:265 Exodeoxyribonuclease
blastp_pdb 3g1k_A 1 199 + 199 Gaps:42 59.25 265 36.94 2e-16 mol:protein length:265 Exodeoxyribonuclease
blastp_uniprot_sprot sp|Q5E9N9|APEX2_BOVIN 1 666 + 666 Gaps:95 99.22 514 32.94 2e-44 DNA-(apurinic or apyrimidinic site) lyase 2 OS Bos taurus GN APEX2 PE 2 SV 1
blastp_uniprot_sprot sp|Q9UBZ4|APEX2_HUMAN 1 666 + 666 Gaps:131 99.23 518 31.91 3e-43 DNA-(apurinic or apyrimidinic site) lyase 2 OS Homo sapiens GN APEX2 PE 1 SV 1
blastp_uniprot_sprot sp|Q68G58|APEX2_MOUSE 1 666 + 666 Gaps:105 99.22 516 32.42 6e-41 DNA-(apurinic or apyrimidinic site) lyase 2 OS Mus musculus GN Apex2 PE 1 SV 1
blastp_uniprot_sprot sp|P87175|APN2_SCHPO 1 665 + 665 Gaps:46 62.33 523 34.36 5e-31 DNA-(apurinic or apyrimidinic site) lyase 2 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN apn2 PE 1 SV 1
blastp_uniprot_sprot sp|P38207|APN2_YEAST 1 207 + 207 Gaps:26 42.88 520 29.60 5e-18 DNA-(apurinic or apyrimidinic site) lyase 2 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN APN2 PE 1 SV 1
blastp_uniprot_sprot sp|P27864|RRP1_DROME 1 256 + 256 Gaps:51 31.37 679 29.58 4e-11 Recombination repair protein 1 OS Drosophila melanogaster GN Rrp1 PE 1 SV 2
blastp_uniprot_sprot sp|P0A1A9|EX3_SALTY 1 218 + 218 Gaps:46 64.93 268 33.33 3e-10 Exodeoxyribonuclease III OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN xthA PE 3 SV 1
blastp_uniprot_sprot sp|P0A1B0|EX3_SALTI 1 218 + 218 Gaps:46 64.93 268 33.33 3e-10 Exodeoxyribonuclease III OS Salmonella typhi GN xthA PE 3 SV 1
blastp_uniprot_sprot sp|Q8K203|NEIL3_MOUSE 618 667 + 50 Gaps:6 7.26 606 59.09 3e-07 Endonuclease 8-like 3 OS Mus musculus GN Neil3 PE 1 SV 1
blastp_uniprot_sprot sp|Q3MHN7|NEIL3_BOVIN 618 667 + 50 Gaps:6 7.26 606 56.82 9e-07 Endonuclease 8-like 3 OS Bos taurus GN NEIL3 PE 2 SV 2

16 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 529 669 141 PTHR22748 none none IPR004808
ProSiteProfiles 1 301 301 PS51435 none AP endonucleases family 1 profile. IPR004808
PANTHER 1 292 292 PTHR22748 none none IPR004808
PANTHER 388 455 68 PTHR22748 none none IPR004808
PANTHER 1 292 292 PTHR22748:SF4 none none none
PANTHER 388 455 68 PTHR22748:SF4 none none none
PANTHER 529 669 141 PTHR22748:SF4 none none none
Pfam 618 668 51 PF06839 none GRF zinc finger IPR010666
ProSitePatterns 30 39 10 PS00726 none AP endonucleases family 1 signature 1. IPR020847
Gene3D 351 420 70 G3DSA:3.60.10.10 none none IPR005135
Pfam 4 239 236 PF03372 none Endonuclease/Exonuclease/phosphatase family IPR005135
SUPERFAMILY 353 418 66 SSF56219 none none IPR005135
Gene3D 1 238 238 G3DSA:3.60.10.10 none none IPR005135
SUPERFAMILY 129 246 118 SSF56219 none none IPR005135
SUPERFAMILY 1 94 94 SSF56219 none none IPR005135
TIGRFAM 1 239 239 TIGR00633 none xth: exodeoxyribonuclease III (xth) IPR004808

0 Localization

16 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Champenoux_2015_nPriLBD_3P Qrob_Chr10 10 v_15000_157 v_15000_310 15,68 15,9 15,91 lod 2.4 5.5
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2014_nLBD*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,25 0 35,55 lod 2,5951 6
Bourran2_2014_nP*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,19 0 31,97 lod 2,8472 6
Bourran2_2002_QTL11_peak_Bud_burst_A4 Qrob_Chr06 6 s_1C41PA_791 s_1AM1AV_1141 19,17 0 34,57 lod 2,3 2,9
Bourran2_2014_aSeqBC_3P Qrob_Chr06 6 v_506_189 v_686_77 30,72 13,58 43,48 lod 2,2746 6,3
Bourran2_2014_aSeqBC*_A4 Qrob_Chr06 6 s_2F5MK3_712 v_444_355 27,13 14,86 39,46 lod 3,7847 9,8
Bourran2_2014_nEpis*_3P Qrob_Chr08 8 s_1DA4QW_688 s_1DNI7D_820 17,96 0 37,75 lod 2,9745 7,5
Bourran2_2014_nEpis*_A4 Qrob_Chr07 7 v_12400_446 s_1BPEBU_1211 6,93 0 15,13 lod 4,7411 11
Bourran2_2014_nFork*_3P Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 34,28 7,43 41,48 lod 2,4044 5,5
Bourran2_2014_nLBD_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 37,41 9,8 50,1 lod 1,9524 4,1
Bourran2_2014_nPriBD_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 34,51 3,36 51,86 lod 1,6747 3,9
Bourran2_2014_nSecLBD_A4 Qrob_Chr07 7 v_8327_222 s_1A4WGY_363 16,04 0 44,69 lod 2,6373 6,5
Bourran2_2014_vEpiBC_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 37,55 14,41 50,01 lod 1,7882 4,8
Champenoux_2015_nEpis_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 26,53 25,47 27,72 lod 4.4 8.9
Champenoux_2015_nP_3P Qrob_Chr06 6 s_1A386O_228 s_1AYZFS_603 27,03 26,47 27,34 lod 2.8 7.2

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 81   Mitochondrion 4 0.073 0.579 NON-PLANT 81