Protein : Qrob_P0049540.2 Q. robur
Protein Identifier  ? Qrob_P0049540.2 Organism . Name  Quercus robur
Score  91.0 Score Type  egn
Protein Description  (M=1) PF00512//PF01590 - His Kinase A (phospho-acceptor) domain // GAF domain Code Enzyme  EC:2.7.11.1
Gene Prediction Quality  validated Protein length 

Sequence

Length: 590  
Kegg Orthology  K14509
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0 Synonyms

5 GO Terms

Identifier Name Description
GO:0005515 protein binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0007165 signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
GO:0004871 signal transducer activity Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
GO:0000155 phosphorelay sensor kinase activity Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.

28 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|rcu:RCOM_0608080 1 583 + 583 Gaps:6 76.93 763 80.58 0.0 ethylene receptor putative
blastp_kegg lcl|fve:101311008 1 583 + 583 Gaps:8 76.59 769 76.91 0.0 protein EIN4-like
blastp_kegg lcl|pper:PRUPE_ppa001846mg 1 583 + 583 Gaps:5 77.51 756 79.18 0.0 hypothetical protein
blastp_kegg lcl|pmum:103318678 1 583 + 583 Gaps:5 77.51 756 78.67 0.0 protein EIN4
blastp_kegg lcl|vvi:100249603 1 583 + 583 Gaps:7 76.84 760 77.57 0.0 protein EIN4-like
blastp_kegg lcl|cic:CICLE_v10018972mg 1 584 + 584 Gaps:12 77.06 763 77.21 0.0 hypothetical protein
blastp_kegg lcl|cit:102578051 1 584 + 584 Gaps:12 77.06 763 77.04 0.0 ETR3 ethylene response 3
blastp_kegg lcl|mdm:103451053 1 583 + 583 Gaps:5 77.51 756 75.77 0.0 ETR5 protein EIN4
blastp_kegg lcl|pop:POPTR_0013s04140g 1 583 + 583 Gaps:6 76.93 763 78.36 0.0 POPTRDRAFT_806893 putative ethylene receptor family protein
blastp_kegg lcl|pxb:103954372 1 583 + 583 Gaps:5 77.51 756 75.94 0.0 protein EIN4-like
blastp_uniprot_sprot sp|Q9ZTP3|EIN4_ARATH 1 583 + 583 Gaps:10 77.15 766 64.64 0.0 Protein EIN4 OS Arabidopsis thaliana GN EIN4 PE 1 SV 1
blastp_uniprot_sprot sp|Q0WPQ2|ETR2_ARATH 1 583 + 583 Gaps:40 76.71 773 56.66 0.0 Ethylene receptor 2 OS Arabidopsis thaliana GN ETR2 PE 1 SV 2
blastp_uniprot_sprot sp|P93825|ERS2_ARATH 7 540 + 534 Gaps:29 85.43 645 50.45 5e-171 Ethylene response sensor 2 OS Arabidopsis thaliana GN ERS2 PE 1 SV 2
blastp_uniprot_sprot sp|Q9M7M1|ETR1_PRUPE 22 583 + 562 Gaps:11 76.29 738 41.56 7e-141 Ethylene receptor OS Prunus persica GN ETR1 PE 2 SV 1
blastp_uniprot_sprot sp|Q41342|ETR1_SOLLC 22 583 + 562 Gaps:13 74.67 754 42.10 2e-140 Ethylene receptor 1 OS Solanum lycopersicum GN ETR1 PE 1 SV 1
blastp_uniprot_sprot sp|O82436|ETR1_CUCMN 22 583 + 562 Gaps:30 75.95 740 42.70 3e-140 Ethylene receptor 1 OS Cucumis melo var. cantalupensis GN ETR1 PE 2 SV 1
blastp_uniprot_sprot sp|P49333|ETR1_ARATH 24 543 + 520 Gaps:12 69.65 738 44.75 3e-140 Ethylene receptor 1 OS Arabidopsis thaliana GN ETR1 PE 1 SV 1
blastp_uniprot_sprot sp|Q9SSY6|ETR1_CUCSA 22 583 + 562 Gaps:30 75.95 740 42.53 7e-140 Ethylene receptor 1 OS Cucumis sativus GN ETR1 PE 2 SV 1
blastp_uniprot_sprot sp|O81122|ETR1_MALDO 24 583 + 560 Gaps:11 75.71 741 41.89 2e-139 Ethylene receptor OS Malus domestica GN ETR1 PE 2 SV 1
blastp_uniprot_sprot sp|O49230|ETR1_BRAOL 24 538 + 515 Gaps:11 69.39 735 44.51 5e-139 Ethylene receptor 1 OS Brassica oleracea GN ETR1 PE 2 SV 1
rpsblast_cdd gnl|CDD|163083 339 510 + 172 Gaps:1 17.67 968 26.32 8e-16 TIGR02956 TMAO_torS TMAO reductase sytem sensor TorS. This protein TorS is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA) a cognate chaperone (TorD) and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518) HAMP (pfam00672) phosphoacceptor (pfam00512) and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072).
rpsblast_cdd gnl|CDD|182968 341 584 + 244 Gaps:56 25.03 919 30.87 8e-13 PRK11107 PRK11107 hybrid sensory histidine kinase BarA Provisional.
rpsblast_cdd gnl|CDD|183148 340 513 + 174 Gaps:19 20.90 914 26.18 3e-10 PRK11466 PRK11466 hybrid sensory histidine kinase TorS Provisional.
rpsblast_cdd gnl|CDD|201875 178 327 + 150 Gaps:9 100.00 143 23.78 4e-09 pfam01590 GAF GAF domain. This domain is present in cGMP-specific phosphodiesterases adenylyl and guanylyl cyclases phytochromes FhlA and NifA. Adenylyl and guanylyl cyclases catalyze ATP and GTP to the second messengers cAMP and cGMP respectively these products up-regulating catalytic activity by binding to the regulatory GAF domain(s). The opposite hydrolysis reaction is catalyzed by phosphodiesterase. cGMP-dependent 3' 5'-cyclic phosphodiesterase catalyzes the conversion of guanosine 3' 5'-cyclic phosphate to guanosine 5'-phosphate. Here too cGMP regulates catalytic activity by GAF-domain binding. Phytochromes are regulatory photoreceptors in plants and bacteria which exist in two thermally-stable states that are reversibly inter-convertible by light: the Pr state absorbs maximally in the red region of the spectrum while the Pfr state absorbs maximally in the far-red region. This domain is also found in FhlA (formate hydrogen lyase transcriptional activator) and NifA a transcriptional activator which is required for activation of most Nif operons which are directly involved in nitrogen fixation. NifA interacts with sigma-54.
rpsblast_cdd gnl|CDD|30987 308 510 + 203 Gaps:8 58.63 336 21.32 2e-07 COG0642 BaeS Signal transduction histidine kinase [Signal transduction mechanisms].
rpsblast_cdd gnl|CDD|201275 363 428 + 66 none 100.00 66 30.30 3e-07 pfam00512 HisKA His Kinase A (phospho-acceptor) domain. Dimerisation and phospho-acceptor domain of histidine kinases.
rpsblast_cdd gnl|CDD|197695 363 428 + 66 none 100.00 66 30.30 5e-07 smart00388 HisKA His Kinase A (phosphoacceptor) domain. Dimerisation and phosphoacceptor domain of histidine kinases.
rpsblast_kog gnl|CDD|35739 21 581 + 561 Gaps:23 74.30 786 36.47 1e-106 KOG0519 KOG0519 KOG0519 Sensory transduction histidine kinase [Signal transduction mechanisms].

27 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 528 542 15 PTHR24423 none none none
PANTHER 567 584 18 PTHR24423 none none none
PANTHER 5 510 506 PTHR24423 none none none
PANTHER 5 510 506 PTHR24423:SF426 none none none
Phobius 134 589 456 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Pfam 364 428 65 PF00512 none His Kinase A (phospho-acceptor) domain IPR003661
Gene3D 360 423 64 G3DSA:1.10.287.130 none none IPR003661
Gene3D 157 335 179 G3DSA:3.30.450.40 none none IPR029016
PANTHER 528 542 15 PTHR24423:SF426 none none none
PANTHER 567 584 18 PTHR24423:SF426 none none none
SMART 178 337 160 SM00065 none Domain present in phytochromes and cGMP-specific phosphodiesterases. IPR003018
Phobius 1 3 3 SIGNAL_PEPTIDE_N_REGION none N-terminal region of a signal peptide. none
Phobius 70 89 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 64 69 6 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
SUPERFAMILY 181 330 150 SSF55781 none none IPR029016
Phobius 13 20 8 SIGNAL_PEPTIDE_C_REGION none C-terminal region of a signal peptide. none
Phobius 21 43 23 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Coils 333 357 25 Coil none none none
Phobius 1 20 20 SIGNAL_PEPTIDE none Signal peptide region none
ProSiteProfiles 370 589 220 PS50109 "Reactome:REACT_1046" Histidine kinase domain profile. IPR005467
Phobius 90 108 19 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
SMART 363 428 66 SM00388 none His Kinase A (phosphoacceptor) domain IPR003661
Phobius 44 63 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 109 133 25 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Pfam 180 327 148 PF01590 none GAF domain IPR003018
Phobius 4 12 9 SIGNAL_PEPTIDE_H_REGION none Hydrophobic region of a signal peptide. none
SUPERFAMILY 348 429 82 SSF47384 none none IPR009082

5 Localization

Analysis Start End Length
TMHMM 107 129 22
SignalP_GRAM_NEGATIVE 1 19 18
TMHMM 46 63 17
TMHMM 73 95 22
SignalP_EUK 1 20 19

18 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Champenoux_2015_nPriLBD_3P Qrob_Chr10 10 v_15000_157 v_15000_310 15,68 15,9 15,91 lod 2.4 5.5
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2014_nLBD*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,25 0 35,55 lod 2,5951 6
Bourran2_2014_nP*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,19 0 31,97 lod 2,8472 6
Bourran2_2002_QTL11_peak_Bud_burst_A4 Qrob_Chr06 6 s_1C41PA_791 s_1AM1AV_1141 19,17 0 34,57 lod 2,3 2,9
Bourran2_2014_aSeqBC_3P Qrob_Chr06 6 v_506_189 v_686_77 30,72 13,58 43,48 lod 2,2746 6,3
Bourran2_2014_aSeqBC*_A4 Qrob_Chr06 6 s_2F5MK3_712 v_444_355 27,13 14,86 39,46 lod 3,7847 9,8
Bourran2_2014_nEpis*_3P Qrob_Chr08 8 s_1DA4QW_688 s_1DNI7D_820 17,96 0 37,75 lod 2,9745 7,5
Bourran2_2014_nEpis*_A4 Qrob_Chr07 7 v_12400_446 s_1BPEBU_1211 6,93 0 15,13 lod 4,7411 11
Bourran2_2014_nFork*_3P Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 34,28 7,43 41,48 lod 2,4044 5,5
Bourran2_2014_nLBD_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 37,41 9,8 50,1 lod 1,9524 4,1
Bourran2_2014_nPriBD_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 34,51 3,36 51,86 lod 1,6747 3,9
Bourran2_2014_nPriLBD*_3P Qrob_Chr11 11 v_12066_307 s_1B15GJ_447 3,37 0,57 16,17 lod 3,4299 6,9
Bourran2_2014_nSecLBD_A4 Qrob_Chr07 7 v_8327_222 s_1A4WGY_363 16,04 0 44,69 lod 2,6373 6,5
Bourran2_2014_vEpiBC_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 37,55 14,41 50,01 lod 1,7882 4,8
Champenoux_2015_nEpis_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 26,53 25,47 27,72 lod 4.4 8.9
Champenoux_2015_nP_3P Qrob_Chr06 6 s_1A386O_228 s_1AYZFS_603 27,03 26,47 27,34 lod 2.8 7.2
Bourran2_2014_nPriBD*_3P Qrob_Chr06 6 s_1B6WLL_980 v_10064_133 11,49 0 31,52 lod 4,1208 9,1

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 20   Secretory pathway 1 0.942 0.016 NON-PLANT 20