GO Term : GO:1990500 eif4e-cup complex GO

Namespace  cellular_component Obsolete  false
description  A protein complex that causes translational repression in Drosophila. Prevents assembly of ribosomes at the mRNA by interfacing with a sequence-specific RNA-binding protein leading to recruitment of the CCR4 complex and consequently, reduction of the mRNA's poly(A) tail length. The complex is also required for dorso-ventral pattern formation in the embryo.

0 Cross References

1 Ontology

Name
GO

20 Parents

Identifier Name Description
GO:0005737 cytoplasm All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0030529 ribonucleoprotein complex A macromolecular complex containing both protein and RNA molecules.
GO:0043234 protein complex A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
GO:0044424 intracellular part Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0032991 macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0044444 cytoplasmic part Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0044422 organelle part Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
GO:0043226 organelle Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
GO:0043229 intracellular organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0043228 non-membrane-bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
GO:0043232 intracellular non-membrane-bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
GO:0000932 cytoplasmic mRNA processing body A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. mRNA processing and binding proteins are localized to these foci.
GO:0036464 cytoplasmic ribonucleoprotein granule A ribonucleoprotein granule located in the cytoplasm.
GO:0035770 ribonucleoprotein granule A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions.
GO:1903502 translation repressor complex A protein complex which is capable of translation repressor activity.
GO:1990500 eif4e-cup complex A protein complex that causes translational repression in Drosophila. Prevents assembly of ribosomes at the mRNA by interfacing with a sequence-specific RNA-binding protein leading to recruitment of the CCR4 complex and consequently, reduction of the mRNA's poly(A) tail length. The complex is also required for dorso-ventral pattern formation in the embryo.

0 Protein

24 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:1903502 GO:1990500
part of GO:0000932 GO:1990500
is_a GO:0044444 GO:1990500
is_a GO:0044422 GO:1990500
is_a GO:0043234 GO:1990500
part of GO:0044424 GO:1990500
part of GO:0043232 GO:1990500
is_a GO:0044424 GO:1990500
part of GO:0005623 GO:1990500
is_a GO:0044464 GO:1990500
part of GO:0005622 GO:1990500
is_a GO:0005575 GO:1990500
part of GO:0005575 GO:1990500
part of GO:0030529 GO:1990500
part of GO:0036464 GO:1990500
part of GO:0043226 GO:1990500
part of GO:0035770 GO:1990500
part of GO:0044464 GO:1990500
part of GO:0043228 GO:1990500
part of GO:0043229 GO:1990500
part of GO:0044444 GO:1990500
part of GO:0005737 GO:1990500
is_a GO:0032991 GO:1990500
part of GO:0032991 GO:1990500

1 Synonyms

Name Type
eukaryotic translation initiation factor 4E-cup complex synonym