GO Term : GO:1990455 PTEN phosphatase complex GO

Namespace  cellular_component Obsolete  false
description  A phospholipid phosphatase complex that catalyses the hydrolysis of the second messenger PtdIns (3,4,5)P3. Will also dephosphorylate PtdIns(3,4)P2, PtdIns3P, and Ins(1,3,4,5)P4. Dimerization is critical for its lipid phosphatase function.

0 Cross References

1 Ontology

Name
GO

9 Parents

Identifier Name Description
GO:0043234 protein complex A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
GO:1902494 catalytic complex A protein complex which is capable of catalytic activity.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0032991 macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:1903293 phosphatase complex A protein complex which is capable of phosphatase activity.
GO:1904144 phosphatidylinositol phosphate phosphatase complex A protein complex which is capable of phosphatidylinositol phosphate phosphatase activity.
GO:1990455 PTEN phosphatase complex A phospholipid phosphatase complex that catalyses the hydrolysis of the second messenger PtdIns (3,4,5)P3. Will also dephosphorylate PtdIns(3,4)P2, PtdIns3P, and Ins(1,3,4,5)P4. Dimerization is critical for its lipid phosphatase function.

0 Protein

9 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0044464 GO:1990455
part of GO:0005623 GO:1990455
is_a GO:1904144 GO:1990455
is_a GO:1902494 GO:1990455
part of GO:0005575 GO:1990455
is_a GO:1903293 GO:1990455
is_a GO:0032991 GO:1990455
is_a GO:0005575 GO:1990455
is_a GO:0043234 GO:1990455

3 Synonyms

Name Type
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN homodimer synonym
phosphatase and tensin homolog deleted on chromosome ten homodimer synonym
phosphatase and tensin homolog synonym