GO Term : GO:1990162 histone deacetylase activity (H3-K4 specific) GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 4) + H2O = histone H3 L-lysine (position 4) + acetate. This reaction represents the removal of an acetyl group from lysine at position 4 of the histone H3 protein.

0 Cross References

1 Ontology

Name
GO

9 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide.
GO:0004407 histone deacetylase activity Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0019213 deacetylase activity Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.
GO:0033558 protein deacetylase activity Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate.
GO:1990162 histone deacetylase activity (H3-K4 specific) Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 4) + H2O = histone H3 L-lysine (position 4) + acetate. This reaction represents the removal of an acetyl group from lysine at position 4 of the histone H3 protein.

0 Protein

8 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0004407 GO:1990162
is_a GO:0019213 GO:1990162
is_a GO:0033558 GO:1990162
is_a GO:0003824 GO:1990162
is_a GO:0016811 GO:1990162
is_a GO:0016810 GO:1990162
is_a GO:0003674 GO:1990162
is_a GO:0016787 GO:1990162

0 Synonyms