12 Parents
| Identifier | Name | Description |
|---|---|---|
| GO:0003824 | catalytic activity | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
| GO:0016787 | hydrolase activity | Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. |
| GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds. |
| GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide. |
| GO:0004407 | histone deacetylase activity | Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes. |
| GO:0003674 | molecular_function | Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. |
| GO:0019213 | deacetylase activity | Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. |
| GO:0033558 | protein deacetylase activity | Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate. |
| GO:0017136 | NAD-dependent histone deacetylase activity | Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone. |
| GO:0034979 | NAD-dependent protein deacetylase activity | Catalysis of the removal of one or more acetyl groups from a protein, requiring NAD. |
| GO:0034739 | histone deacetylase activity (H4-K16 specific) | Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein. |
| GO:0097372 | NAD-dependent histone deacetylase activity (H3-K18 specific) | Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 18) + H2O = histone H3 L-lysine (position 18) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 18 of the histone H3 protein. |
11 Relations
| Relationship |
Parent Term . Identifier |
Child Term . Identifier |
|---|---|---|
| is_a | GO:0017136 | GO:0097372 |
| is_a | GO:0034739 | GO:0097372 |
| is_a | GO:0016810 | GO:0097372 |
| is_a | GO:0003674 | GO:0097372 |
| is_a | GO:0016811 | GO:0097372 |
| is_a | GO:0034979 | GO:0097372 |
| is_a | GO:0004407 | GO:0097372 |
| is_a | GO:0019213 | GO:0097372 |
| is_a | GO:0003824 | GO:0097372 |
| is_a | GO:0033558 | GO:0097372 |
| is_a | GO:0016787 | GO:0097372 |
