GO Term : GO:0048297 negative regulation of isotype switching to IgA isotypes GO

Namespace  biological_process Obsolete  false
description  Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgA isotypes.

0 Cross References

1 Ontology

Name
GO

119 Parents

Identifier Name Description
GO:0007275 multicellular organismal development The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0006310 DNA recombination Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
GO:0032502 developmental process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
GO:0006139 nucleobase-containing compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0006259 DNA metabolic process Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0006725 cellular aromatic compound metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
GO:0045910 negative regulation of DNA recombination Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0090304 nucleic acid metabolic process Any cellular metabolic process involving nucleic acids.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0046483 heterocycle metabolic process The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
GO:0034641 cellular nitrogen compound metabolic process The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
GO:1901360 organic cyclic compound metabolic process The chemical reactions and pathways involving organic cyclic compound.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.
GO:0000018 regulation of DNA recombination Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.
GO:0051052 regulation of DNA metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.
GO:0019219 regulation of nucleobase-containing compound metabolic process Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0031323 regulation of cellular metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
GO:0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.

0 Protein

177 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0045829 GO:0048297
negatively regulates GO:0048290 GO:0048297
is_a GO:0048296 GO:0048297
negatively regulates GO:0042113 GO:0048297
regulates GO:0008150 GO:0048297
negatively regulates GO:0006807 GO:0048297
negatively regulates GO:0006139 GO:0048297
regulates GO:0008152 GO:0048297
negatively regulates GO:0032501 GO:0048297
negatively regulates GO:0032502 GO:0048297
is_a GO:0002713 GO:0048297
is_a GO:0002712 GO:0048297
negatively regulates GO:0002520 GO:0048297
is_a GO:0002682 GO:0048297
negatively regulates GO:0002263 GO:0048297
is_a GO:0002683 GO:0048297
negatively regulates GO:0045190 GO:0048297
is_a GO:0051172 GO:0048297
regulates GO:0002285 GO:0048297
is_a GO:0051171 GO:0048297
negatively regulates GO:0046649 GO:0048297
is_a GO:0002890 GO:0048297
is_a GO:0002819 GO:0048297
regulates GO:0006259 GO:0048297
negatively regulates GO:0002312 GO:0048297
regulates GO:0009987 GO:0048297
regulates GO:0019724 GO:0048297
regulates GO:0006955 GO:0048297
regulates GO:0002200 GO:0048297
negatively regulates GO:0044260 GO:0048297

7 Synonyms

Name Type
down regulation of isotype switching to IgA isotypes synonym
down-regulation of isotype switching to IgA isotypes synonym
negative regulation of isotype switch recombination to IgA isotypes synonym
inhibition of isotype switching to IgA isotypes synonym
downregulation of isotype switching to IgA isotypes synonym
negative regulation of class switching to IgA isotypes synonym
negative regulation of class switch recombination to IgA isotypes synonym