GO Term : GO:0046403 polynucleotide 3'-phosphatase activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the reaction: 3'-phosphopolynucleotide + H2O = a polynucleotide + phosphate. Hydrolyzes the free 3'-phosphate resulting from single strand breaks in DNA due to oxidative damage.

0 Cross References

1 Ontology

Name
GO

8 Parents

Identifier Name Description
GO:0016791 phosphatase activity Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0016788 hydrolase activity, acting on ester bonds Catalysis of the hydrolysis of any ester bond.
GO:0042578 phosphoric ester hydrolase activity Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0098518 polynucleotide phosphatase activity Catalysis of the reaction: phosphopolynucleotide + H2O = polynucleotide + phosphate.
GO:0046403 polynucleotide 3'-phosphatase activity Catalysis of the reaction: 3'-phosphopolynucleotide + H2O = a polynucleotide + phosphate. Hydrolyzes the free 3'-phosphate resulting from single strand breaks in DNA due to oxidative damage.

0 Protein

7 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0098518 GO:0046403
is_a GO:0042578 GO:0046403
is_a GO:0003674 GO:0046403
is_a GO:0016788 GO:0046403
is_a GO:0016787 GO:0046403
is_a GO:0003824 GO:0046403
is_a GO:0016791 GO:0046403

5 Synonyms

Name Type
2'(3')-polynucleotidase activity synonym
5'-polynucleotidekinase 3'-phosphatase activity synonym
DNA 3'-phosphatase activity synonym
deoxyribonucleate 3'-phosphatase activity synonym
polynucleotide 3'-phosphohydrolase activity synonym