GO Term : GO:0036166 phenotypic switching GO

Namespace  biological_process Obsolete  false
description  A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns. For example, Candida albicans switches from a unicellular form to an invasive multicellular filamentous form upon infection of host tissue, and from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues.

0 Cross References

1 Ontology

Name
GO

3 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0036166 phenotypic switching A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns. For example, Candida albicans switches from a unicellular form to an invasive multicellular filamentous form upon infection of host tissue, and from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues.

0 Protein

21 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0009987 GO:0036166
is_a GO:0008150 GO:0036166
is_a GO:0036166 GO:0036167
part of GO:0036166 GO:0044663
part of GO:0036166 GO:0044664
regulates GO:0036166 GO:0100057
positively regulates GO:0036166 GO:0100058
regulates GO:0036166 GO:0100058
negatively regulates GO:0036166 GO:0100059
regulates GO:0036166 GO:0100059
regulates GO:0036166 GO:1900239
negatively regulates GO:0036166 GO:1900240
regulates GO:0036166 GO:1900240
positively regulates GO:0036166 GO:1900241
regulates GO:0036166 GO:1900241
part of GO:0036166 GO:1900447
regulates GO:0036166 GO:1900545
positively regulates GO:0036166 GO:1900546
regulates GO:0036166 GO:1900546
negatively regulates GO:0036166 GO:1900547
regulates GO:0036166 GO:1900547

1 Synonyms

Name Type
phenotypic dimorphism synonym