GO Term : GO:0035575 histone demethylase activity (H4-K20 specific) GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the reaction: histone H4 N6-methyl-L-lysine (position 20) + 2-oxoglutarate + O2 = histone H4 L-lysine (position 20) + succinate + formaldehyde + CO2. This reaction is the removal of a methyl group from lysine at position 20 of the histone H4 protein.

0 Cross References

1 Ontology

Name
GO

5 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0032451 demethylase activity Catalysis of the removal of a methyl group from a substrate.
GO:0032452 histone demethylase activity Catalysis of the removal of a methyl group from a histone.
GO:0035575 histone demethylase activity (H4-K20 specific) Catalysis of the reaction: histone H4 N6-methyl-L-lysine (position 20) + 2-oxoglutarate + O2 = histone H4 L-lysine (position 20) + succinate + formaldehyde + CO2. This reaction is the removal of a methyl group from lysine at position 20 of the histone H4 protein.

0 Protein

4 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0032452 GO:0035575
is_a GO:0032451 GO:0035575
is_a GO:0003824 GO:0035575
is_a GO:0003674 GO:0035575

0 Synonyms