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GO:0003824
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catalytic activity
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Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
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GO:0015238
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drug transmembrane transporter activity
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Enables the directed movement of a drug from one side of a membrane to the other. A drug is any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease. |
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GO:0016787
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hydrolase activity
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Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. |
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GO:0022857
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transmembrane transporter activity
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Enables the transfer of a substance from one side of a membrane to the other. |
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GO:0005215
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transporter activity
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Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells. |
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GO:0042626
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ATPase activity, coupled to transmembrane movement of substances
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Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane. |
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GO:0016887
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ATPase activity
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Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction. |
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GO:0016817
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hydrolase activity, acting on acid anhydrides
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Catalysis of the hydrolysis of any acid anhydride. |
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GO:0016820
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hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
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Catalysis of the hydrolysis of an acid anhydride to directly drive the transport of a substance across a membrane. |
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GO:0016818
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hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
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Catalysis of the hydrolysis of any acid anhydride which contains phosphorus. |
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GO:0016462
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pyrophosphatase activity
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Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments. |
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GO:0003674
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molecular_function
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Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. |
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GO:0022804
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active transmembrane transporter activity
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Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction. |
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GO:0017111
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nucleoside-triphosphatase activity
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Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate. |
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GO:0042623
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ATPase activity, coupled
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Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane. |
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GO:0015405
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P-P-bond-hydrolysis-driven transmembrane transporter activity
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Primary active transport of a solute across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source. |
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GO:0043492
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ATPase activity, coupled to movement of substances
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Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance. |
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GO:0015399
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primary active transmembrane transporter activity
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Catalysis of the transfer of a solute from one side of the membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is powered by a primary energy source, directly using ATP. Primary energy sources known to be coupled to transport are chemical, electrical and solar sources. |
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GO:0090484
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drug transporter activity
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Enables the directed movement of a drug into, out of or within a cell, or between cells. A drug is any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease. |
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GO:0008559
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xenobiotic-transporting ATPase activity
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Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out). |
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GO:0042910
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xenobiotic transporter activity
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Enables the directed movement of a xenobiotic, a compound foreign to living organisms, into, out of or within a cell, or between cells. |
