14 Parents
| Identifier | Name | Description |
|---|---|---|
| GO:0004871 | signal transducer activity | Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. |
| GO:0004872 | receptor activity | Combining with an extracellular or intracellular messenger to initiate a change in cell activity. |
| GO:0004930 | G-protein coupled receptor activity | Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. |
| GO:0004888 | transmembrane signaling receptor activity | Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
| GO:0003674 | molecular_function | Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. |
| GO:0038023 | signaling receptor activity | Receiving a signal and transmitting the signal in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. |
| GO:0060089 | molecular transducer activity | The molecular function that accepts an input of one form and creates an output of a different form. |
| GO:0004896 | cytokine receptor activity | Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
| GO:0008528 | G-protein coupled peptide receptor activity | Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. |
| GO:0001653 | peptide receptor activity | Combining with an extracellular or intracellular peptide to initiate a change in cell activity. |
| GO:0001637 | G-protein coupled chemoattractant receptor activity | Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. |
| GO:0004918 | interleukin-8 receptor activity | Combining with interleukin-8 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
| GO:0016494 | C-X-C chemokine receptor activity | Combining with a C-X-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X-C chemokine has a single amino acid between the first two cysteines of the characteristic four cysteine motif. |
| GO:0004950 | chemokine receptor activity | Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. |
13 Relations
| Relationship |
Parent Term . Identifier |
Child Term . Identifier |
|---|---|---|
| is_a | GO:0016494 | GO:0004918 |
| is_a | GO:0004896 | GO:0004918 |
| is_a | GO:0004872 | GO:0004918 |
| is_a | GO:0003674 | GO:0004918 |
| is_a | GO:0004871 | GO:0004918 |
| is_a | GO:0004950 | GO:0004918 |
| is_a | GO:0038023 | GO:0004918 |
| is_a | GO:0004930 | GO:0004918 |
| is_a | GO:0004888 | GO:0004918 |
| is_a | GO:0060089 | GO:0004918 |
| is_a | GO:0001637 | GO:0004918 |
| is_a | GO:0008528 | GO:0004918 |
| is_a | GO:0001653 | GO:0004918 |
