Protein : Qrob_P0758210.2 Q. robur

Protein Identifier  ? Qrob_P0758210.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=2) PTHR11680:SF1 - SERINE HYDROXYMETHYLTRANSFERASE Code Enzyme  EC:2.1.2.1
Gene Prediction Quality  validated Protein length 

Sequence

Length: 519  
Kegg Orthology  K00600

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0 Synonyms

6 GO Terms

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0030170 pyridoxal phosphate binding Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0004372 glycine hydroxymethyltransferase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.
GO:0006544 glycine metabolic process The chemical reactions and pathways involving glycine, aminoethanoic acid.
GO:0006563 L-serine metabolic process The chemical reactions and pathways involving L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.

41 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pmum:103319426 3 516 + 514 Gaps:12 99.62 520 90.93 0.0 serine hydroxymethyltransferase 2 mitochondrial
blastp_kegg lcl|pper:PRUPE_ppa004304mg 3 516 + 514 Gaps:9 99.61 517 91.26 0.0 hypothetical protein
blastp_kegg lcl|mdm:103441699 6 516 + 511 Gaps:11 99.61 516 90.08 0.0 serine hydroxymethyltransferase mitochondrial
blastp_kegg lcl|pop:POPTR_0002s10990g 5 516 + 512 Gaps:11 99.42 516 89.67 0.0 POPTRDRAFT_643921 hypothetical protein
blastp_kegg lcl|vvi:100245411 5 516 + 512 Gaps:9 99.42 516 89.28 0.0 serine hydroxymethyltransferase mitochondrial-like
blastp_kegg lcl|vvi:100243424 1 516 + 516 Gaps:10 99.61 518 89.15 0.0 serine hydroxymethyltransferase mitochondrial-like
blastp_kegg lcl|mdm:103402023 16 516 + 501 Gaps:7 98.45 516 89.37 0.0 serine hydroxymethyltransferase mitochondrial-like
blastp_kegg lcl|sot:102599354 1 516 + 516 Gaps:9 99.61 519 88.01 0.0 serine hydroxymethyltransferase mitochondrial-like
blastp_kegg lcl|pop:POPTR_0008s00350g 1 516 + 516 Gaps:12 99.62 520 88.22 0.0 POPTRDRAFT_421205 Serine hydroxymethyltransferase family protein
blastp_kegg lcl|csv:101229487 5 516 + 512 Gaps:9 99.42 516 87.52 0.0 serine hydroxymethyltransferase mitochondrial-like
blastp_pdb 3ou5_A 39 511 + 473 Gaps:6 95.71 490 61.83 0.0 mol:protein length:490 Serine hydroxymethyltransferase mitochondria
blastp_pdb 1eji_D 46 509 + 464 Gaps:2 97.49 478 60.30 0.0 mol:protein length:478 SERINE HYDROXYMETHYLTRANSFERASE
blastp_pdb 1eji_C 46 509 + 464 Gaps:2 97.49 478 60.30 0.0 mol:protein length:478 SERINE HYDROXYMETHYLTRANSFERASE
blastp_pdb 1eji_B 46 509 + 464 Gaps:2 97.49 478 60.30 0.0 mol:protein length:478 SERINE HYDROXYMETHYLTRANSFERASE
blastp_pdb 1eji_A 46 509 + 464 Gaps:2 97.49 478 60.30 0.0 mol:protein length:478 SERINE HYDROXYMETHYLTRANSFERASE
blastp_pdb 1bj4_A 52 509 + 458 Gaps:3 97.66 470 60.35 0.0 mol:protein length:470 PROTEIN (SERINE HYDROXYMETHYLTRANSFERASE)
blastp_pdb 1ls3_D 37 509 + 473 Gaps:5 98.96 483 58.16 0.0 mol:protein length:483 Serine Hydroxymethyltransferase
blastp_pdb 1ls3_C 37 509 + 473 Gaps:5 98.96 483 58.16 0.0 mol:protein length:483 Serine Hydroxymethyltransferase
blastp_pdb 1ls3_B 37 509 + 473 Gaps:5 98.96 483 58.16 0.0 mol:protein length:483 Serine Hydroxymethyltransferase
blastp_pdb 1ls3_A 37 509 + 473 Gaps:5 98.96 483 58.16 0.0 mol:protein length:483 Serine Hydroxymethyltransferase
blastp_uniprot_sprot sp|P34899|GLYM_PEA 1 517 + 517 Gaps:10 99.81 518 86.85 0.0 Serine hydroxymethyltransferase mitochondrial OS Pisum sativum PE 1 SV 1
blastp_uniprot_sprot sp|Q94C74|GLYM2_ARATH 5 516 + 512 Gaps:12 99.42 517 86.58 0.0 Serine hydroxymethyltransferase 2 mitochondrial OS Arabidopsis thaliana GN SHM2 PE 1 SV 2
blastp_uniprot_sprot sp|P50433|GLYM_SOLTU 1 516 + 516 Gaps:10 99.61 518 86.43 0.0 Serine hydroxymethyltransferase mitochondrial OS Solanum tuberosum PE 2 SV 1
blastp_uniprot_sprot sp|Q9SZJ5|GLYM1_ARATH 1 516 + 516 Gaps:9 99.61 517 85.83 0.0 Serine hydroxymethyltransferase 1 mitochondrial OS Arabidopsis thaliana GN SHM1 PE 1 SV 1
blastp_uniprot_sprot sp|P49357|GLYM1_FLAPR 1 516 + 516 Gaps:11 99.61 517 86.60 0.0 Serine hydroxymethyltransferase 1 mitochondrial OS Flaveria pringlei PE 2 SV 1
blastp_uniprot_sprot sp|P49358|GLYM2_FLAPR 30 516 + 487 Gaps:1 94.00 517 89.09 0.0 Serine hydroxymethyltransferase 2 mitochondrial OS Flaveria pringlei PE 2 SV 1
blastp_uniprot_sprot sp|Q7S5N8|GLYM_NEUCR 50 505 + 456 Gaps:18 86.45 546 63.35 0.0 Putative serine hydroxymethyltransferase mitochondrial OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) GN cbs-2 PE 3 SV 2
blastp_uniprot_sprot sp|Q10104|GLYM_SCHPO 23 504 + 482 Gaps:13 98.57 488 63.62 0.0 Serine hydroxymethyltransferase mitochondrial OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN shm2 PE 3 SV 2
blastp_uniprot_sprot sp|P34897|GLYM_HUMAN 39 511 + 473 Gaps:6 93.06 504 61.83 0.0 Serine hydroxymethyltransferase mitochondrial OS Homo sapiens GN SHMT2 PE 1 SV 3
blastp_uniprot_sprot sp|Q3SZ20|GLYM_BOVIN 39 510 + 472 Gaps:6 92.86 504 61.75 0.0 Serine hydroxymethyltransferase mitochondrial OS Bos taurus GN SHMT2 PE 2 SV 1

9 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 19 518 500 PTHR11680:SF1 none none none
PANTHER 19 518 500 PTHR11680 "KEGG:00260+2.1.2.1","KEGG:00460+2.1.2.1","KEGG:00630+2.1.2.1","KEGG:00670+2.1.2.1","KEGG:00680+2.1.2.1","MetaCyc:PWY-1622","MetaCyc:PWY-181","MetaCyc:PWY-2161","MetaCyc:PWY-2201","MetaCyc:PWY-3661","MetaCyc:PWY-3661-1","MetaCyc:PWY-3841","MetaCyc:PWY-5497","UniPathway:UPA00193","UniPathway:UPA00288";signature_desc=SERINE HYDROXYMETHYLTRANSFERASE none IPR001085
PIRSF 37 513 477 PIRSF000412 "KEGG:00260+2.1.2.1","KEGG:00460+2.1.2.1","KEGG:00630+2.1.2.1","KEGG:00670+2.1.2.1","KEGG:00680+2.1.2.1","MetaCyc:PWY-1622","MetaCyc:PWY-181","MetaCyc:PWY-2161","MetaCyc:PWY-2201","MetaCyc:PWY-3661","MetaCyc:PWY-3661-1","MetaCyc:PWY-3841","MetaCyc:PWY-5497","UniPathway:UPA00193","UniPathway:UPA00288" none IPR001085
Pfam 57 453 397 PF00464 "KEGG:00260+2.1.2.1","KEGG:00460+2.1.2.1","KEGG:00630+2.1.2.1","KEGG:00670+2.1.2.1","KEGG:00680+2.1.2.1","MetaCyc:PWY-1622","MetaCyc:PWY-181","MetaCyc:PWY-2161","MetaCyc:PWY-2201","MetaCyc:PWY-3661","MetaCyc:PWY-3661-1","MetaCyc:PWY-3841","MetaCyc:PWY-5497","UniPathway:UPA00193","UniPathway:UPA00288" Serine hydroxymethyltransferase IPR001085
Gene3D 355 510 156 G3DSA:3.90.1150.10 none none IPR015422
Gene3D 85 354 270 G3DSA:3.40.640.10 none none IPR015421
ProSitePatterns 279 295 17 PS00096 "KEGG:00260+2.1.2.1","KEGG:00460+2.1.2.1","KEGG:00630+2.1.2.1","KEGG:00670+2.1.2.1","KEGG:00680+2.1.2.1","MetaCyc:PWY-1622","MetaCyc:PWY-181","MetaCyc:PWY-2161","MetaCyc:PWY-2201","MetaCyc:PWY-3661","MetaCyc:PWY-3661-1","MetaCyc:PWY-3841","MetaCyc:PWY-5497","UniPathway:UPA00193","UniPathway:UPA00288" Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. IPR019798
Coils 483 504 22 Coil none none none
SUPERFAMILY 51 508 458 SSF53383 none none IPR015424

0 Localization

1 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2015_nEpis_3P Qrob_Chr12 12 s_1AOES6_1466 s_1B0DDG_1094 28,97 28,55 30,1 lod 3.6 8.4

0 Targeting