Protein : Qrob_P0754530.2 Q. robur
Protein Identifier  ? Qrob_P0754530.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) 1.4.1.24 - 3-dehydroquinate synthase II. Code Enzyme  EC:1.4.1.24
Gene Prediction Quality  validated Protein length 

Sequence

Length: 405  
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0009073 aromatic amino acid family biosynthetic process The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
GO:0003856 3-dehydroquinate synthase activity Catalysis of the reaction: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate.

23 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pmum:103329984 4 404 + 401 Gaps:7 95.75 424 78.57 0.0 uncharacterized LOC103329984
blastp_kegg lcl|pop:POPTR_0017s11670g 22 404 + 383 Gaps:15 92.94 411 77.49 0.0 POPTRDRAFT_259008 hypothetical protein
blastp_kegg lcl|mdm:103421496 5 404 + 400 Gaps:8 94.92 413 76.53 0.0 uncharacterized LOC103421496
blastp_kegg lcl|fve:101295727 5 404 + 400 Gaps:13 96.53 403 77.89 0.0 3-dehydroquinate synthase-like
blastp_kegg lcl|cit:102626217 5 404 + 400 Gaps:21 94.51 401 78.10 0.0 hypothetical protein
blastp_kegg lcl|vvi:100262957 50 404 + 355 none 96.47 368 78.31 0.0 3-dehydroquinate synthase-like
blastp_kegg lcl|rcu:RCOM_0855180 7 404 + 398 Gaps:25 92.36 419 73.64 0.0 hypothetical protein
blastp_kegg lcl|pvu:PHAVU_004G027100g 49 403 + 355 Gaps:1 80.64 439 79.66 0.0 hypothetical protein
blastp_kegg lcl|gmx:100806285 6 403 + 398 Gaps:6 90.05 442 73.12 0.0 uncharacterized LOC100806285
blastp_kegg lcl|csv:101226693 53 404 + 352 Gaps:1 82.98 423 77.21 0.0 3-dehydroquinate synthase-like
blastp_uniprot_sprot sp|Q2NI00|DHQS_METST 54 403 + 350 Gaps:35 99.44 359 41.46 2e-76 3-dehydroquinate synthase OS Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3) GN aroB' PE 3 SV 1
blastp_uniprot_sprot sp|A0B6K6|DHQS_METTP 59 404 + 346 Gaps:34 96.69 362 43.43 3e-76 3-dehydroquinate synthase OS Methanosaeta thermophila (strain DSM 6194 / PT) GN aroB' PE 3 SV 2
blastp_uniprot_sprot sp|Q58646|DHQS_METJA 137 403 + 267 Gaps:11 70.91 361 49.61 4e-75 3-dehydroquinate synthase OS Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) GN aroB' PE 1 SV 1
blastp_uniprot_sprot sp|O26680|DHQS_METTH 145 404 + 260 Gaps:13 66.58 374 51.81 2e-74 3-dehydroquinate synthase OS Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) GN aroB' PE 3 SV 2
blastp_uniprot_sprot sp|A4G0J1|DHQS_METM5 139 403 + 265 Gaps:11 70.36 361 48.43 9e-73 3-dehydroquinate synthase OS Methanococcus maripaludis (strain C5 / ATCC BAA-1333) GN aroB' PE 3 SV 1
blastp_uniprot_sprot sp|Q12UJ7|DHQS_METBU 145 403 + 259 Gaps:18 65.17 379 53.85 2e-72 3-dehydroquinate synthase OS Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M) GN aroB' PE 3 SV 2
blastp_uniprot_sprot sp|A6UW69|DHQS_META3 145 403 + 259 Gaps:10 68.78 362 49.00 5e-72 3-dehydroquinate synthase OS Methanococcus aeolicus (strain Nankai-3 / ATCC BAA-1280) GN aroB' PE 3 SV 1
blastp_uniprot_sprot sp|Q6M1B0|DHQS_METMP 139 403 + 265 Gaps:11 70.36 361 47.64 7e-72 3-dehydroquinate synthase OS Methanococcus maripaludis (strain S2 / LL) GN aroB' PE 3 SV 1
blastp_uniprot_sprot sp|A5UJ82|DHQS_METS3 145 403 + 259 Gaps:11 67.39 368 50.40 9e-72 3-dehydroquinate synthase OS Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) GN aroB' PE 3 SV 1
blastp_uniprot_sprot sp|A9A8T5|DHQS_METM6 139 403 + 265 Gaps:11 70.36 361 46.46 5e-71 3-dehydroquinate synthase OS Methanococcus maripaludis (strain C6 / ATCC BAA-1332) GN aroB' PE 3 SV 1
rpsblast_cdd gnl|CDD|190172 54 404 + 351 Gaps:18 100.00 347 45.24 1e-115 pfam01959 DHQS 3-dehydroquinate synthase (EC 4.6.1.3). 3-Dehydroquinate synthase is an enzyme in the common pathway of aromatic amino acid biosynthesis that catalyzes the conversion of 3-deoxy-D-arabino-heptulosonic acid 7-phosphate (DAHP) into 3-dehydroquinic acid. This synthesis of aromatic amino acids is an essential metabolic function for most prokaryotic as well as lower eukaryotic cells including plants. The pathway is absent in humans therefore DHQS represents a potential target for the development of novel and selective antimicrobial agents. Owing to the threat posed by the spread of pathogenic bacteria resistant to many currently used antimicrobial drugs there is clearly a need to develop new anti-infective drugs acting at novel targets. A further potential use for DHQS inhibitors is as herbicides.
rpsblast_cdd gnl|CDD|179407 54 403 + 350 Gaps:20 99.42 344 43.86 3e-93 PRK02290 PRK02290 3-dehydroquinate synthase Provisional.
rpsblast_cdd gnl|CDD|31654 54 403 + 350 Gaps:47 99.20 376 41.02 3e-79 COG1465 COG1465 Predicted alternative 3-dehydroquinate synthase [Amino acid transport and metabolism].

3 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Pfam 54 404 351 PF01959 "KEGG:00400+1.4.1.24","MetaCyc:PWY-6160" 3-dehydroquinate synthase (EC 4.6.1.3) IPR002812
ProDom 137 403 267 PD017907 "KEGG:00400+1.4.1.24","MetaCyc:PWY-6160" 3-DEHYDROQUINATE UPF0245 SYNTHASE LYASE PREDICTED SYNTHASE-LIKE ALTERNATIVE T19N8 MM1272 MK1408 IPR002812
PIRSF 10 404 395 PIRSF006655 "KEGG:00400+1.4.1.24","MetaCyc:PWY-6160" none IPR002812

0 Localization

17 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran1_2003_QTL2_peak_Bud_burst_A4 Qrob_Chr02 2 s_1B0H8U_259 s_1CB1VL_554 17 0 87 lod 3,3 8,7
Bourran2_2004_QTL9_peak_Bud_burst_3P Qrob_Chr02 2 s_1C34E9_788 v_12238_322 50 25 75 lod 4,4 10,1
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL2_d13Cf Qrob_Chr02 2 s_1AQA4Z_1644 s_1AK5QX_947 53.67 14,01 79,68 lod 5.6594 0.03
Bourran1_2004_QTL2_peak_Bud_burst_3P Qrob_Chr02 2 s_1AW12F_382 s_1A77MR_223 42 6 64 lod 3,6 9,6
Bourran2_2002_QTL7_peak_Bud_burst_3P Qrob_Chr02 2 s_1ANG6_1446 v_11270_161 40 29 52 lod 8,1 16
Bourran2_2002_QTL9_peak_Bud_burst_A4 Qrob_Chr02 2 s_1BFNDA_375 s_1A3VA1_2139 32,5 17 62 lod 3,1 4,2
Bourran2_2003_QTL8_peak_Bud_burst_3P Qrob_Chr02 2 s_1ANG6_1446 v_11270_161 40 0 72 lod 4,4 9,9
Bourran2_2014_nP_A4 Qrob_Chr11 11 s_1B58GB_1413 s_1A5BYY_1671 11,15 0 42,38 lod 1,8913 4,5
Bourran2_2015_nP_A4 Qrob_Chr02 2 s_1A0FUE_1868 s_1A1UAI_500 20,64 20,47 21,36 lod 5.8 10.9
Bourran2_2015_nPriLBD_A4 Qrob_Chr02 2 s_1CP5DI_1183 s_1A63ZX_1277 24,87 24,63 26,18 lod 3.8 7
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL6_d13Cf Qrob_Chr02 2 s_1AEP21_172 v_6048_204 46.33 22,5 65,23 lod 4.972 0.03
Bourran2_2015_nEpis_A4 Qrob_Chr09 9 v_15847_485 v_8329_369 34,94 34,88 37,45 lod 3.1 7
Bourran2_2015_nSecLBD_A4 Qrob_Chr09 9 v_15847_485 v_8329_369 35,81 34,88 37,45 lod 4.4 10.4
Bourran1_2004_QTL3_peak_Bud_burst_A4 Qrob_Chr02 2 s_1B0H8U_259 s_1CB1VL_554 17 0 46 lod 2,9 6,4
Bourran2_2015_nEpiBC_A4 Qrob_Chr07 7 s_1DP9TW_798 v_8128_173 22,61 22,14 22,73 lod 3.1 8.5
Champenoux_2015_nP_A4 Qrob_Chr02 2 s_1BN4CB_644 v_508_128 23,76 23,06 24,51 lod 2.8 6.2
Champenoux_2015_nPriLBD_A4 Qrob_Chr02 2 s_1CP5DI_1183 s_1A63ZX_1277 25,35 24,63 26,18 lod 4.0 8.7

0 Targeting