| Analysis | rpsblast_cdd | Start | 54 |
| End | 404 | Strand | + |
| Length | 351 | Note | Gaps:18 |
| Hit Coverage | 100.00 | Hit Length | 347 |
| Hit Pident | 45.24 | E Val | 1e-115 |
| Hit Description | pfam01959 DHQS 3-dehydroquinate synthase (EC 4.6.1.3). 3-Dehydroquinate synthase is an enzyme in the common pathway of aromatic amino acid biosynthesis that catalyzes the conversion of 3-deoxy-D-arabino-heptulosonic acid 7-phosphate (DAHP) into 3-dehydroquinic acid. This synthesis of aromatic amino acids is an essential metabolic function for most prokaryotic as well as lower eukaryotic cells including plants. The pathway is absent in humans therefore DHQS represents a potential target for the development of novel and selective antimicrobial agents. Owing to the threat posed by the spread of pathogenic bacteria resistant to many currently used antimicrobial drugs there is clearly a need to develop new anti-infective drugs acting at novel targets. A further potential use for DHQS inhibitors is as herbicides. | Hit Pcons | 17.29 |
| Name | Qrob_P0754530.2 |
| Protein Identifier |
Organism . Name |
Score | Score Type | Protein Description | Alias (in v1) | Code Enzyme | Gene Prediction Quality |
|---|---|---|---|---|---|---|---|
| Qrob_P0754530.2 | Quercus robur | 100.0 | egn | (M=1) 1.4.1.24 - 3-dehydroquinate synthase II. | EC:1.4.1.24 | validated |
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