Protein : Qrob_P0752810.2 Q. robur

Protein Identifier  ? Qrob_P0752810.2 Organism . Name  Quercus robur
Score  71.2 Score Type  egn
Protein Description  (M=3) 1.2.4.2 - Oxoglutarate dehydrogenase (succinyl-transferring). Code Enzyme  EC:1.2.4.2
Gene Prediction Quality  validated Protein length 

Sequence

Length: 1020  
Kegg Orthology  K00164

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0 Synonyms

6 GO Terms

Identifier Name Description
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0030976 thiamine pyrophosphate binding Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
GO:0006099 tricarboxylic acid cycle A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide.
GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2.

42 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|rcu:RCOM_0465620 1 1019 + 1019 none 99.80 1021 91.85 0.0 2-oxoglutarate dehydrogenase putative (EC:1.2.4.2)
blastp_kegg lcl|pop:POPTR_0010s21610g 1 1019 + 1019 none 99.80 1021 91.27 0.0 POPTRDRAFT_724772 2-oxoglutarate dehydrogenase E1 component family protein
blastp_kegg lcl|cmo:103500204 1 1018 + 1018 Gaps:1 99.71 1022 91.66 0.0 2-oxoglutarate dehydrogenase mitochondrial-like
blastp_kegg lcl|csv:101222022 1 1018 + 1018 Gaps:1 99.71 1022 91.46 0.0 2-oxoglutarate dehydrogenase mitochondrial-like
blastp_kegg lcl|tcc:TCM_042828 1 1019 + 1019 none 99.61 1023 91.66 0.0 2-oxoglutarate dehydrogenase E1 component isoform 1
blastp_kegg lcl|cit:102623642 1 1017 + 1017 none 99.32 1024 91.05 0.0 2-oxoglutarate dehydrogenase mitochondrial-like
blastp_kegg lcl|cic:CICLE_v10018656mg 1 1017 + 1017 none 99.32 1024 91.05 0.0 hypothetical protein
blastp_kegg lcl|pop:POPTR_0008s05150g 1 1019 + 1019 none 99.80 1021 90.28 0.0 POPTRDRAFT_820318 2-oxoglutarate dehydrogenase E1 component family protein
blastp_kegg lcl|pper:PRUPE_ppa000728mg 1 1019 + 1019 none 99.80 1021 90.28 0.0 hypothetical protein
blastp_kegg lcl|pmum:103332610 1 1019 + 1019 none 99.80 1021 90.28 0.0 2-oxoglutarate dehydrogenase mitochondrial-like
blastp_pdb 2jgd_B 62 1015 + 954 Gaps:80 99.04 933 44.70 0.0 mol:protein length:933 2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT
blastp_pdb 2jgd_A 62 1015 + 954 Gaps:80 99.04 933 44.70 0.0 mol:protein length:933 2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT
blastp_pdb 2yid_D 112 1012 + 901 Gaps:86 99.88 868 44.98 0.0 mol:protein length:868 2-OXOGLUTARATE DECARBOXYLASE
blastp_pdb 2yid_C 112 1012 + 901 Gaps:86 99.88 868 44.98 0.0 mol:protein length:868 2-OXOGLUTARATE DECARBOXYLASE
blastp_pdb 2yid_B 112 1012 + 901 Gaps:86 99.88 868 44.98 0.0 mol:protein length:868 2-OXOGLUTARATE DECARBOXYLASE
blastp_pdb 2yid_A 112 1012 + 901 Gaps:86 99.88 868 44.98 0.0 mol:protein length:868 2-OXOGLUTARATE DECARBOXYLASE
blastp_pdb 2yic_D 112 1012 + 901 Gaps:86 99.88 868 44.98 0.0 mol:protein length:868 2-OXOGLUTARATE DECARBOXYLASE
blastp_pdb 2yic_C 112 1012 + 901 Gaps:86 99.88 868 44.98 0.0 mol:protein length:868 2-OXOGLUTARATE DECARBOXYLASE
blastp_pdb 2yic_B 112 1012 + 901 Gaps:86 99.88 868 44.98 0.0 mol:protein length:868 2-OXOGLUTARATE DECARBOXYLASE
blastp_pdb 2yic_A 112 1012 + 901 Gaps:86 99.88 868 44.98 0.0 mol:protein length:868 2-OXOGLUTARATE DECARBOXYLASE
blastp_uniprot_sprot sp|Q54JE4|ODO1_DICDI 35 1012 + 978 Gaps:40 97.73 1013 52.83 0.0 2-oxoglutarate dehydrogenase mitochondrial OS Dictyostelium discoideum GN ogdh PE 3 SV 1
blastp_uniprot_sprot sp|O74378|ODO1_SCHPO 63 1012 + 950 Gaps:57 95.64 1009 50.88 0.0 2-oxoglutarate dehydrogenase mitochondrial OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN kgd1 PE 3 SV 1
blastp_uniprot_sprot sp|P20967|ODO1_YEAST 63 1014 + 952 Gaps:61 95.96 1014 49.74 0.0 2-oxoglutarate dehydrogenase mitochondrial OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN KGD1 PE 1 SV 2
blastp_uniprot_sprot sp|O61199|ODO1_CAEEL 64 1012 + 949 Gaps:74 94.17 1029 50.15 0.0 2-oxoglutarate dehydrogenase mitochondrial OS Caenorhabditis elegans GN ogdh-1 PE 1 SV 2
blastp_uniprot_sprot sp|Q623T0|ODO1_CAEBR 64 1012 + 949 Gaps:75 94.06 1027 50.41 0.0 2-oxoglutarate dehydrogenase mitochondrial OS Caenorhabditis briggsae GN CBG01737 PE 3 SV 1
blastp_uniprot_sprot sp|Q60HE2|ODO1_MACFA 26 1012 + 987 Gaps:84 97.65 1023 48.95 0.0 2-oxoglutarate dehydrogenase mitochondrial OS Macaca fascicularis GN OGDH PE 2 SV 1
blastp_uniprot_sprot sp|Q02218|ODO1_HUMAN 26 1012 + 987 Gaps:84 97.65 1023 48.95 0.0 2-oxoglutarate dehydrogenase mitochondrial OS Homo sapiens GN OGDH PE 1 SV 3
blastp_uniprot_sprot sp|Q5RCB8|ODO1_PONAB 26 1012 + 987 Gaps:84 97.65 1023 48.85 0.0 2-oxoglutarate dehydrogenase mitochondrial OS Pongo abelii GN OGDH PE 2 SV 1
blastp_uniprot_sprot sp|Q6P6Z8|ODO1_XENLA 63 1012 + 950 Gaps:73 94.71 1021 50.26 0.0 2-oxoglutarate dehydrogenase mitochondrial OS Xenopus laevis GN ogdh PE 2 SV 1
blastp_uniprot_sprot sp|Q5XI78|ODO1_RAT 10 1012 + 1003 Gaps:90 98.83 1023 48.76 0.0 2-oxoglutarate dehydrogenase mitochondrial OS Rattus norvegicus GN Ogdh PE 1 SV 1

16 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PIRSF 59 1014 956 PIRSF000157 "KEGG:00020+1.2.4.2","KEGG:00310+1.2.4.2","KEGG:00380+1.2.4.2","MetaCyc:PWY-5084" none IPR011603
Gene3D 653 851 199 G3DSA:3.40.50.970 none none IPR029061
Phobius 1 5 5 SIGNAL_PEPTIDE_N_REGION none N-terminal region of a signal peptide. none
SUPERFAMILY 619 855 237 SSF52518 none none IPR029061
TIGRFAM 113 1011 899 TIGR00239 "KEGG:00020+1.2.4.2","KEGG:00310+1.2.4.2","KEGG:00380+1.2.4.2","MetaCyc:PWY-5084" 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component IPR011603
Pfam 635 850 216 PF02779 none Transketolase, pyrimidine binding domain IPR005475
Phobius 6 15 10 SIGNAL_PEPTIDE_H_REGION none Hydrophobic region of a signal peptide. none
SMART 636 849 214 SM00861 none Transketolase, pyrimidine binding domain IPR005475
Phobius 16 20 5 SIGNAL_PEPTIDE_C_REGION none C-terminal region of a signal peptide. none
Phobius 1 20 20 SIGNAL_PEPTIDE none Signal peptide region none
PANTHER 18 1017 1000 PTHR23152:SF6 none none none
Gene3D 197 585 389 G3DSA:3.40.50.970 none none IPR029061
Phobius 21 1019 999 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Pfam 244 564 321 PF00676 none Dehydrogenase E1 component IPR001017
PANTHER 18 1017 1000 PTHR23152 "KEGG:00020+1.2.4.2","KEGG:00310+1.2.4.2","KEGG:00380+1.2.4.2","MetaCyc:PWY-5084";signature_desc=2-OXOGLUTARATE DEHYDROGENASE none IPR011603
SUPERFAMILY 151 581 431 SSF52518 none none IPR029061

0 Localization

2 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Champenoux_2015_nSeqBC_A4 Qrob_Chr08 8 v_AD7YD13_501 s_1A7IED_780 43,44 43,42 43,99 lod 3.7 8.9

0 Targeting