Protein : Qrob_P0683440.2 Q. robur
Protein Identifier  ? Qrob_P0683440.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) K10849 - DNA excision repair protein ERCC-1 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 417  
Kegg Orthology  K10849
Paste the following link
Lists
This Protein isn't in any lists. Upload a list.

Sequence Feature Displayer

Protein Sequence Displayer

J Browse Displayer

0 Synonyms

4 GO Terms

Identifier Name Description
GO:0005634 nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GO:0003684 damaged DNA binding Interacting selectively and non-covalently with damaged DNA.
GO:0006281 DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
GO:0004519 endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.

26 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pxb:103928320 4 415 + 412 Gaps:20 99.24 397 77.16 0.0 DNA excision repair protein ERCC-1
blastp_kegg lcl|mdm:103427694 4 415 + 412 Gaps:18 99.24 397 76.14 0.0 DNA excision repair protein ERCC-1-like
blastp_kegg lcl|pmum:103344672 4 416 + 413 Gaps:34 98.80 416 74.94 0.0 DNA excision repair protein ERCC-1
blastp_kegg lcl|pper:PRUPE_ppa006720mg 4 416 + 413 Gaps:19 99.50 398 77.27 0.0 hypothetical protein
blastp_kegg lcl|fve:101302568 5 416 + 412 Gaps:33 99.74 380 77.57 0.0 DNA excision repair protein ERCC-1-like
blastp_kegg lcl|gmx:100777022 25 415 + 391 Gaps:35 95.67 393 76.06 0.0 DNA excision repair protein ERCC-1-like
blastp_kegg lcl|pvu:PHAVU_007G181700g 9 405 + 397 Gaps:34 99.49 393 72.63 0.0 hypothetical protein
blastp_kegg lcl|mtr:MTR_1g082570 1 415 + 415 Gaps:37 99.75 401 72.00 0.0 DNA excision repair protein ERCC-1
blastp_kegg lcl|rcu:RCOM_1430840 21 412 + 392 Gaps:32 92.86 392 77.20 0.0 excision repair cross-complementing 1 ercc1 putative
blastp_kegg lcl|cam:101508212 12 415 + 404 Gaps:33 59.97 652 72.12 0.0 DNA excision repair protein ERCC-1-like
blastp_pdb 2a1i_A 134 262 + 129 none 88.36 146 58.14 5e-49 mol:protein length:146 DNA excision repair protein ERCC-1
blastp_pdb 2jpd_A 134 257 + 124 none 91.85 135 58.87 3e-47 mol:protein length:135 DNA excision repair protein ERCC-1
blastp_pdb 2jnw_A 134 248 + 115 none 86.47 133 60.00 1e-43 mol:protein length:133 DNA excision repair protein ERCC-1
blastp_pdb 2a1j_B 254 331 + 78 none 85.71 91 55.13 2e-22 mol:protein length:91 DNA excision repair protein ERCC-1
blastp_pdb 1z00_A 255 331 + 77 none 86.52 89 54.55 1e-21 mol:protein length:89 DNA excision repair protein ERCC-1
blastp_uniprot_sprot sp|Q9MA98|ERCC1_ARATH 1 391 + 391 Gaps:20 94.39 410 65.89 1e-173 DNA excision repair protein ERCC-1 OS Arabidopsis thaliana GN ERCC1 PE 2 SV 1
blastp_uniprot_sprot sp|P07992|ERCC1_HUMAN 113 331 + 219 Gaps:6 75.76 297 54.22 1e-83 DNA excision repair protein ERCC-1 OS Homo sapiens GN ERCC1 PE 1 SV 1
blastp_uniprot_sprot sp|Q1LZ75|ERCC1_BOVIN 63 331 + 269 Gaps:11 93.20 294 47.08 1e-81 DNA excision repair protein ERCC-1 OS Bos taurus GN ERCC1 PE 2 SV 1
blastp_uniprot_sprot sp|P07903|ERCC1_MOUSE 80 331 + 252 Gaps:3 85.57 298 48.63 1e-80 DNA excision repair protein ERCC-1 OS Mus musculus GN Ercc1 PE 2 SV 2
blastp_uniprot_sprot sp|Q06182|SWI10_SCHPO 134 328 + 195 none 77.38 252 46.67 1e-56 Mating-type switching protein swi10 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN swi10 PE 3 SV 1
blastp_uniprot_sprot sp|Q55GG6|ERCC1_DICDI 131 328 + 198 Gaps:15 41.44 514 28.17 2e-20 DNA excision repair protein ERCC-1 OS Dictyostelium discoideum GN ercc1 PE 3 SV 1
blastp_uniprot_sprot sp|P06838|RAD10_YEAST 135 249 + 115 Gaps:8 56.67 210 31.93 7e-13 DNA repair protein RAD10 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN RAD10 PE 1 SV 1
rpsblast_cdd gnl|CDD|129685 134 245 + 112 none 100.00 112 59.82 4e-37 TIGR00597 rad10 DNA repair protein rad10. All proteins in this family for which functions are known are components in a multiprotein endonuclease complex (usually made up of Rad1 and Rad10 homologs). This complex is used primarily for nucleotide excision repair but also for some aspects of recombination repair. This family is based on the phylogenomic analysis of JA Eisen (1999 Ph.D. Thesis Stanford University).
rpsblast_cdd gnl|CDD|34838 136 328 + 193 Gaps:7 83.93 224 29.79 2e-29 COG5241 RAD10 Nucleotide excision repair endonuclease NEF1 RAD10 subunit [DNA replication recombination and repair].
rpsblast_cdd gnl|CDD|190768 134 201 + 68 none 100.00 68 60.29 2e-26 pfam03834 Rad10 Binding domain of DNA repair protein Ercc1 (rad10/Swi10). Ercc1 and XPF (xeroderma pigmentosum group F-complementing protein) are two structure-specific endonucleases of a class of seven containing an ERCC4 domain. Together they form an obligate complex that functions primarily in nucleotide excision repair (NER) a versatile pathway able to detect and remove a variety of DNA lesions induced by UV light and environmental carcinogens and secondarily in DNA interstrand cross-link repair and telomere maintenance. This domain in fact binds simultaneously to both XPF and single-stranded DNA this ternary complex explains the important role of Ercc1 in targeting its catalytic XPF partner to the NER pre-incision complex.
rpsblast_kog gnl|CDD|38052 38 331 + 294 Gaps:42 100.00 254 50.00 1e-76 KOG2841 KOG2841 KOG2841 Structure-specific endonuclease ERCC1-XPF ERCC1 component [Replication recombination and repair].

9 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 1 375 375 PTHR12749 none none none
TIGRFAM 134 245 112 TIGR00597 none rad10: DNA repair protein rad10 IPR004579
SUPERFAMILY 134 260 127 SSF52980 none none IPR011335
PANTHER 1 375 375 PTHR12749:SF0 none none none
Pfam 134 200 67 PF03834 none Binding domain of DNA repair protein Ercc1 (rad10/Swi10) IPR004579
SUPERFAMILY 257 328 72 SSF47781 "Reactome:REACT_216" none IPR010994
Pfam 273 322 50 PF14520 none Helix-hairpin-helix domain none
Gene3D 273 326 54 G3DSA:1.10.150.20 none none none
ProDom 134 258 125 PD013585 none REPAIR DNA EXCISION ERCC1 NUCLEOTIDE DNA-BINDING HYDROLASE PROTEIN ENDONUCLEASE DAMAGE IPR004579

0 Localization

6 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nLBD*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 34,91 16,12 53,62 lod 2,4961 5,2
Bourran2_2014_rEpiBC*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 35,77 14,11 55,31 lod 2,9413 6,2
Bourran_2000_2002_QTL6_Delta.F Qrob_Chr03 3 s_2HYXJ2_207 s_1AUAXK_317 29.12 6,3 45,37 lod 3.1666 0.026
Bourran2_2014_nLBD_3P Qrob_Chr03 3 s_1ET7H8_604 s_1BYNB5_834 23,73 0 46,72 lod 1,7573 3,8
PM_1999_QTL14_peak_Bud_burst_3P Qrob_Chr03 3 s_2F0SI1_756 v_6056_735 11,78 3,78 50,78 lod 2,5 4,5
Bourran2_2014_rEpiBC*_3P Qrob_Chr03 3 s_1A3B3X_1163 s_1DKGMO_450 23,04 4,92 41,12 lod 2,5668 7

0 Targeting