Protein : Qrob_P0591890.2 Q. robur
Protein Identifier  ? Qrob_P0591890.2 Organism . Name  Quercus robur
Score  28.1 Score Type  egn
Protein Description  (M=4) K02350 - DNA polymerase zeta subunit [EC:2.7.7.7] Code Enzyme  EC:2.7.7.7
Gene Prediction Quality  validated Protein length 

Sequence

Length: 1962  
Kegg Orthology  K02350
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0 Synonyms

8 GO Terms

Identifier Name Description
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0003676 nucleic acid binding Interacting selectively and non-covalently with any nucleic acid.
GO:0006281 DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
GO:0000166 nucleotide binding Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
GO:0003887 DNA-directed DNA polymerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group.
GO:0008408 3'-5' exonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.
GO:0016035 zeta DNA polymerase complex A heterodimeric DNA polymerase complex that catalyzes error-prone DNA synthesis in contexts such as translesion synthesis and double-stranded break repair. First characterized in Saccharomyces, in which the subunits are Rev3p and Rev7p; a third protein, Rev1p, is often associated with the polymerase dimer.
GO:0019985 translesion synthesis The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide.

43 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|tcc:TCM_026537 23 1961 + 1939 Gaps:234 94.69 2035 61.24 0.0 Recovery protein 3 isoform 1
blastp_kegg lcl|gmx:100777934 2 1961 + 1960 Gaps:287 95.80 1976 58.11 0.0 DNA polymerase zeta catalytic subunit-like
blastp_kegg lcl|csv:101222413 2 1958 + 1957 Gaps:233 67.43 2868 55.12 0.0 uncharacterized LOC101222413
blastp_kegg lcl|pvu:PHAVU_006G091300g 2 1961 + 1960 Gaps:316 95.77 1963 57.45 0.0 hypothetical protein
blastp_kegg lcl|pmum:103344607 2 1958 + 1957 Gaps:222 64.69 2699 66.21 0.0 DNA polymerase zeta catalytic subunit
blastp_kegg lcl|pper:PRUPE_ppa000111mg 2 1961 + 1960 Gaps:276 94.64 1771 67.42 0.0 hypothetical protein
blastp_kegg lcl|cit:102622531 3 1961 + 1959 Gaps:189 92.98 1808 65.44 0.0 DNA polymerase zeta catalytic subunit-like
blastp_kegg lcl|vvi:100263126 18 1959 + 1942 Gaps:112 55.14 2002 74.55 0.0 uncharacterized LOC100263126
blastp_kegg lcl|rcu:RCOM_1431670 18 1958 + 1941 Gaps:94 54.55 2066 71.69 0.0 DNA polymerase zeta catalytic subunit putative (EC:2.7.7.7)
blastp_kegg lcl|cic:CICLE_v10003639mg 3 1961 + 1959 Gaps:254 92.71 1741 65.92 0.0 hypothetical protein
blastp_pdb 3iay_A 1099 1818 + 720 Gaps:131 71.93 919 29.95 1e-67 mol:protein length:919 DNA polymerase delta catalytic subunit
blastp_pdb 1tgo_A 1165 1822 + 658 Gaps:152 74.26 773 28.75 5e-35 mol:protein length:773 PROTEIN (THERMOSTABLE B DNA POLYMERASE)
blastp_pdb 2vwj_A 1165 1822 + 658 Gaps:152 74.26 773 28.75 5e-35 mol:protein length:773 DNA POLYMERASE
blastp_pdb 2xhb_A 1165 1822 + 658 Gaps:152 74.26 773 28.75 5e-35 mol:protein length:773 DNA POLYMERASE
blastp_pdb 2vwk_A 1165 1822 + 658 Gaps:152 74.26 773 28.75 5e-35 mol:protein length:773 DNA POLYMERASE
blastp_pdb 2jgu_A 1167 1822 + 656 Gaps:149 73.94 775 29.49 2e-34 mol:protein length:775 DNA POLYMERASE
blastp_pdb 1qht_A 1165 1822 + 658 Gaps:142 74.06 775 29.09 2e-34 mol:protein length:775 PROTEIN (DNA POLYMERASE)
blastp_pdb 3a2f_A 1138 1822 + 685 Gaps:149 77.68 775 28.74 5e-34 mol:protein length:775 DNA polymerase
blastp_pdb 2gv9_B 1157 1769 + 613 Gaps:216 54.23 1193 25.66 1e-33 mol:protein length:1193 DNA polymerase
blastp_pdb 2gv9_A 1157 1769 + 613 Gaps:216 54.23 1193 25.66 1e-33 mol:protein length:1193 DNA polymerase
blastp_uniprot_sprot sp|Q766Z3|REV3_ARATH 3 1961 + 1959 Gaps:243 92.54 1890 55.97 0.0 DNA polymerase zeta catalytic subunit OS Arabidopsis thaliana GN REV3 PE 2 SV 1
blastp_uniprot_sprot sp|Q61493|DPOLZ_MOUSE 3 1940 + 1938 Gaps:151 34.40 3122 41.25 0.0 DNA polymerase zeta catalytic subunit OS Mus musculus GN Rev3l PE 1 SV 3
blastp_uniprot_sprot sp|O60673|DPOLZ_HUMAN 3 1940 + 1938 Gaps:164 32.68 3130 42.72 0.0 DNA polymerase zeta catalytic subunit OS Homo sapiens GN REV3L PE 1 SV 2
blastp_uniprot_sprot sp|P14284|DPOZ_YEAST 1080 1952 + 873 Gaps:121 57.18 1504 38.26 2e-179 DNA polymerase zeta catalytic subunit OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN REV3 PE 1 SV 1
blastp_uniprot_sprot sp|Q9P6L6|DPOZ_SCHPO 1066 1937 + 872 Gaps:109 57.09 1480 39.05 2e-165 DNA polymerase zeta catalytic subunit OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN rev3 PE 3 SV 1
blastp_uniprot_sprot sp|P46588|DPOD_CANAX 1099 1949 + 851 Gaps:142 76.20 1038 29.46 3e-80 DNA polymerase delta catalytic subunit OS Candida albicans GN POL3 PE 3 SV 2
blastp_uniprot_sprot sp|P15436|DPOD_YEAST 1099 1941 + 843 Gaps:145 70.56 1097 29.33 3e-76 DNA polymerase delta catalytic subunit OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN POL3 PE 1 SV 4
blastp_uniprot_sprot sp|P52431|DPOD1_MOUSE 1099 1941 + 843 Gaps:132 70.68 1105 30.22 8e-76 DNA polymerase delta catalytic subunit OS Mus musculus GN Pold1 PE 1 SV 2
blastp_uniprot_sprot sp|P97283|DPOD1_MESAU 1099 1941 + 843 Gaps:132 70.81 1103 30.35 1e-75 DNA polymerase delta catalytic subunit OS Mesocricetus auratus GN POLD1 PE 2 SV 1
blastp_uniprot_sprot sp|Q9LRE6|DPOD1_ORYSJ 1101 1940 + 840 Gaps:130 70.41 1105 30.72 3e-75 DNA polymerase delta catalytic subunit OS Oryza sativa subsp. japonica GN POLD1 PE 2 SV 1

30 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 1569 1669 101 G3DSA:3.90.1600.10 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" none IPR023211
Gene3D 1437 1465 29 G3DSA:3.90.1600.10 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" none IPR023211
SUPERFAMILY 1262 1411 150 SSF53098 none none IPR012337
SUPERFAMILY 1100 1229 130 SSF53098 none none IPR012337
SUPERFAMILY 28 92 65 SSF53098 none none IPR012337
Pfam 1860 1933 74 PF14260 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" C4-type zinc-finger of DNA polymerase delta IPR025687
Gene3D 1258 1396 139 G3DSA:3.30.420.10 none none IPR012337
Gene3D 1098 1221 124 G3DSA:3.30.420.10 none none IPR012337
Pfam 1100 1293 194 PF03104 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" DNA polymerase family B, exonuclease domain IPR006133
ProSitePatterns 1592 1600 9 PS00116 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" DNA polymerase family B signature. IPR017964
PANTHER 405 526 122 PTHR10322:SF5 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7";signature_desc=DNA POLYMERASE ZETA CATALYTIC SUBUNIT none IPR030559
PANTHER 1375 1946 572 PTHR10322:SF5 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7";signature_desc=DNA POLYMERASE ZETA CATALYTIC SUBUNIT none IPR030559
PANTHER 155 270 116 PTHR10322:SF5 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7";signature_desc=DNA POLYMERASE ZETA CATALYTIC SUBUNIT none IPR030559
PANTHER 1244 1349 106 PTHR10322:SF5 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7";signature_desc=DNA POLYMERASE ZETA CATALYTIC SUBUNIT none IPR030559
Gene3D 1520 1568 49 G3DSA:1.10.287.690 none none none
PANTHER 3 100 98 PTHR10322:SF5 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7";signature_desc=DNA POLYMERASE ZETA CATALYTIC SUBUNIT none IPR030559
PANTHER 1060 1221 162 PTHR10322:SF5 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7";signature_desc=DNA POLYMERASE ZETA CATALYTIC SUBUNIT none IPR030559
Pfam 1588 1815 228 PF00136 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" DNA polymerase family B IPR006134
Pfam 1397 1587 191 PF00136 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" DNA polymerase family B IPR006134
PRINTS 1558 1570 13 PR00106 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" DNA-directed DNA-polymerase family B signature IPR006172
PRINTS 1590 1598 9 PR00106 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" DNA-directed DNA-polymerase family B signature IPR006172
PRINTS 1449 1462 14 PR00106 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" DNA-directed DNA-polymerase family B signature IPR006172
PANTHER 405 526 122 PTHR10322 none none none
PANTHER 1244 1349 106 PTHR10322 none none none
SMART 1097 1604 508 SM00486 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" DNA polymerase type-B family IPR006172
PANTHER 3 100 98 PTHR10322 none none none
PANTHER 1375 1946 572 PTHR10322 none none none
PANTHER 155 270 116 PTHR10322 none none none
PANTHER 1060 1221 162 PTHR10322 none none none
SUPERFAMILY 1436 1825 390 SSF56672 none none none

0 Localization

6 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nLBD*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 34,91 16,12 53,62 lod 2,4961 5,2
Bourran2_2014_rEpiBC*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 35,77 14,11 55,31 lod 2,9413 6,2
Bourran_2000_2002_QTL6_Delta.F Qrob_Chr03 3 s_2HYXJ2_207 s_1AUAXK_317 29.12 6,3 45,37 lod 3.1666 0.026
Bourran2_2014_nLBD_3P Qrob_Chr03 3 s_1ET7H8_604 s_1BYNB5_834 23,73 0 46,72 lod 1,7573 3,8
PM_1999_QTL14_peak_Bud_burst_3P Qrob_Chr03 3 s_2F0SI1_756 v_6056_735 11,78 3,78 50,78 lod 2,5 4,5
Bourran2_2014_rEpiBC*_3P Qrob_Chr03 3 s_1A3B3X_1163 s_1DKGMO_450 23,04 4,92 41,12 lod 2,5668 7

0 Targeting