Protein : Qrob_P0591680.2 Q. robur
Protein Identifier  ? Qrob_P0591680.2 Organism . Name  Quercus robur
Score  96.0 Score Type  egn
Protein Description  (M=4) K02350 - DNA polymerase zeta subunit [EC:2.7.7.7] Code Enzyme  EC:2.7.7.7
Gene Prediction Quality  validated Protein length 

Sequence

Length: 2122  
Kegg Orthology  K02350
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0 Synonyms

8 GO Terms

Identifier Name Description
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0003676 nucleic acid binding Interacting selectively and non-covalently with any nucleic acid.
GO:0006281 DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
GO:0000166 nucleotide binding Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
GO:0003887 DNA-directed DNA polymerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group.
GO:0008408 3'-5' exonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.
GO:0016035 zeta DNA polymerase complex A heterodimeric DNA polymerase complex that catalyzes error-prone DNA synthesis in contexts such as translesion synthesis and double-stranded break repair. First characterized in Saccharomyces, in which the subunits are Rev3p and Rev7p; a third protein, Rev1p, is often associated with the polymerase dimer.
GO:0019985 translesion synthesis The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide.

43 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|tcc:TCM_026537 1 2121 + 2121 Gaps:174 100.00 2035 63.49 0.0 Recovery protein 3 isoform 1
blastp_kegg lcl|gmx:100777934 1 2121 + 2121 Gaps:257 100.00 1976 60.53 0.0 DNA polymerase zeta catalytic subunit-like
blastp_kegg lcl|csv:101222413 1 2118 + 2118 Gaps:187 70.47 2868 57.94 0.0 uncharacterized LOC101222413
blastp_kegg lcl|pvu:PHAVU_006G091300g 1 2121 + 2121 Gaps:274 100.00 1963 59.96 0.0 hypothetical protein
blastp_kegg lcl|pmum:103344607 8 2118 + 2111 Gaps:199 67.54 2699 69.83 0.0 DNA polymerase zeta catalytic subunit
blastp_kegg lcl|pper:PRUPE_ppa000111mg 8 2121 + 2114 Gaps:187 99.32 1771 71.35 0.0 hypothetical protein
blastp_kegg lcl|cit:102622531 1 2121 + 2121 Gaps:143 97.68 1808 68.46 0.0 DNA polymerase zeta catalytic subunit-like
blastp_kegg lcl|vvi:100263126 1 2119 + 2119 Gaps:138 58.34 2002 76.63 0.0 uncharacterized LOC100263126
blastp_kegg lcl|rcu:RCOM_1431670 1 2118 + 2118 Gaps:140 57.79 2066 73.62 0.0 DNA polymerase zeta catalytic subunit putative (EC:2.7.7.7)
blastp_kegg lcl|mdm:103450935 1009 2121 + 1113 Gaps:93 99.51 1025 75.88 0.0 DNA polymerase zeta catalytic subunit-like
blastp_pdb 3iay_A 1220 1978 + 759 Gaps:128 71.93 919 30.56 8e-70 mol:protein length:919 DNA polymerase delta catalytic subunit
blastp_pdb 2gv9_B 1278 1929 + 652 Gaps:201 54.23 1193 26.89 9e-39 mol:protein length:1193 DNA polymerase
blastp_pdb 2gv9_A 1278 1929 + 652 Gaps:201 54.23 1193 26.89 9e-39 mol:protein length:1193 DNA polymerase
blastp_pdb 2vwk_A 1286 1982 + 697 Gaps:145 74.26 773 29.62 2e-38 mol:protein length:773 DNA POLYMERASE
blastp_pdb 2xhb_A 1286 1982 + 697 Gaps:145 74.26 773 29.62 2e-38 mol:protein length:773 DNA POLYMERASE
blastp_pdb 1tgo_A 1286 1982 + 697 Gaps:145 74.26 773 29.62 2e-38 mol:protein length:773 PROTEIN (THERMOSTABLE B DNA POLYMERASE)
blastp_pdb 2vwj_A 1286 1982 + 697 Gaps:145 74.26 773 29.62 2e-38 mol:protein length:773 DNA POLYMERASE
blastp_pdb 2jgu_A 1288 1982 + 695 Gaps:142 73.94 775 31.06 5e-38 mol:protein length:775 DNA POLYMERASE
blastp_pdb 1qht_A 1286 1982 + 697 Gaps:137 74.06 775 30.14 7e-38 mol:protein length:775 PROTEIN (DNA POLYMERASE)
blastp_pdb 3a2f_A 1259 1982 + 724 Gaps:142 77.68 775 30.23 2e-37 mol:protein length:775 DNA polymerase
blastp_uniprot_sprot sp|Q766Z3|REV3_ARATH 1 2121 + 2121 Gaps:196 92.91 1890 60.14 0.0 DNA polymerase zeta catalytic subunit OS Arabidopsis thaliana GN REV3 PE 2 SV 1
blastp_uniprot_sprot sp|Q61493|DPOLZ_MOUSE 11 2100 + 2090 Gaps:181 38.76 3122 43.06 0.0 DNA polymerase zeta catalytic subunit OS Mus musculus GN Rev3l PE 1 SV 3
blastp_uniprot_sprot sp|O60673|DPOLZ_HUMAN 11 2100 + 2090 Gaps:161 35.21 3130 45.19 0.0 DNA polymerase zeta catalytic subunit OS Homo sapiens GN REV3L PE 1 SV 2
blastp_uniprot_sprot sp|P14284|DPOZ_YEAST 4 2112 + 2109 Gaps:166 75.27 1504 37.63 0.0 DNA polymerase zeta catalytic subunit OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN REV3 PE 1 SV 1
blastp_uniprot_sprot sp|Q9P6L6|DPOZ_SCHPO 40 2097 + 2058 Gaps:121 67.36 1480 38.31 1e-172 DNA polymerase zeta catalytic subunit OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN rev3 PE 3 SV 1
blastp_uniprot_sprot sp|P46588|DPOD_CANAX 1220 2109 + 890 Gaps:147 76.20 1038 31.10 9e-86 DNA polymerase delta catalytic subunit OS Candida albicans GN POL3 PE 3 SV 2
blastp_uniprot_sprot sp|P52431|DPOD1_MOUSE 1220 2101 + 882 Gaps:127 70.68 1105 31.37 8e-81 DNA polymerase delta catalytic subunit OS Mus musculus GN Pold1 PE 1 SV 2
blastp_uniprot_sprot sp|P30316|DPOD_SCHPO 30 2101 + 2072 Gaps:180 86.92 1086 30.72 2e-80 DNA polymerase delta catalytic subunit OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN pol3 PE 1 SV 2
blastp_uniprot_sprot sp|P97283|DPOD1_MESAU 1220 2101 + 882 Gaps:125 70.81 1103 31.24 4e-80 DNA polymerase delta catalytic subunit OS Mesocricetus auratus GN POLD1 PE 2 SV 1
blastp_uniprot_sprot sp|Q9LRE6|DPOD1_ORYSJ 1222 2100 + 879 Gaps:137 70.41 1105 32.26 9e-80 DNA polymerase delta catalytic subunit OS Oryza sativa subsp. japonica GN POLD1 PE 2 SV 1

31 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 1365 1470 106 PTHR10322:SF5 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7";signature_desc=DNA POLYMERASE ZETA CATALYTIC SUBUNIT none IPR030559
PANTHER 1511 2106 596 PTHR10322:SF5 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7";signature_desc=DNA POLYMERASE ZETA CATALYTIC SUBUNIT none IPR030559
Pfam 1220 1414 195 PF03104 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" DNA polymerase family B, exonuclease domain IPR006133
PANTHER 238 371 134 PTHR10322:SF5 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7";signature_desc=DNA POLYMERASE ZETA CATALYTIC SUBUNIT none IPR030559
PANTHER 480 602 123 PTHR10322:SF5 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7";signature_desc=DNA POLYMERASE ZETA CATALYTIC SUBUNIT none IPR030559
PANTHER 1181 1342 162 PTHR10322:SF5 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7";signature_desc=DNA POLYMERASE ZETA CATALYTIC SUBUNIT none IPR030559
PANTHER 1365 1470 106 PTHR10322 none none none
PANTHER 238 371 134 PTHR10322 none none none
PANTHER 1511 2106 596 PTHR10322 none none none
Pfam 2020 2093 74 PF14260 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" C4-type zinc-finger of DNA polymerase delta IPR025687
PANTHER 480 602 123 PTHR10322 none none none
PANTHER 1181 1342 162 PTHR10322 none none none
Pfam 1533 1975 443 PF00136 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" DNA polymerase family B IPR006134
Gene3D 1504 1532 29 G3DSA:3.30.420.10 none none IPR012337
Gene3D 1379 1482 104 G3DSA:3.30.420.10 none none IPR012337
Gene3D 1219 1342 124 G3DSA:3.30.420.10 none none IPR012337
PANTHER 11 183 173 PTHR10322 none none none
ProSitePatterns 1752 1760 9 PS00116 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" DNA polymerase family B signature. IPR017964
SMART 1218 1764 547 SM00486 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" DNA polymerase type-B family IPR006172
PRINTS 1694 1706 13 PR00106 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" DNA-directed DNA-polymerase family B signature IPR006172
PRINTS 1750 1758 9 PR00106 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" DNA-directed DNA-polymerase family B signature IPR006172
PRINTS 1585 1598 14 PR00106 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" DNA-directed DNA-polymerase family B signature IPR006172
PANTHER 11 183 173 PTHR10322:SF5 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7";signature_desc=DNA POLYMERASE ZETA CATALYTIC SUBUNIT none IPR030559
SUPERFAMILY 1514 1532 19 SSF53098 none none IPR012337
SUPERFAMILY 1383 1472 90 SSF53098 none none IPR012337
SUPERFAMILY 1218 1346 129 SSF53098 none none IPR012337
SUPERFAMILY 37 167 131 SSF53098 none none IPR012337
SUPERFAMILY 1572 1985 414 SSF56672 none none none
Gene3D 1656 1707 52 G3DSA:1.10.287.690 none none none
Gene3D 1718 1829 112 G3DSA:3.90.1600.10 "KEGG:00230+2.7.7.7","KEGG:00240+2.7.7.7" none IPR023211

0 Localization

6 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nLBD*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 34,91 16,12 53,62 lod 2,4961 5,2
Bourran2_2014_rEpiBC*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 35,77 14,11 55,31 lod 2,9413 6,2
Bourran_2000_2002_QTL6_Delta.F Qrob_Chr03 3 s_2HYXJ2_207 s_1AUAXK_317 29.12 6,3 45,37 lod 3.1666 0.026
Bourran2_2014_nLBD_3P Qrob_Chr03 3 s_1ET7H8_604 s_1BYNB5_834 23,73 0 46,72 lod 1,7573 3,8
PM_1999_QTL14_peak_Bud_burst_3P Qrob_Chr03 3 s_2F0SI1_756 v_6056_735 11,78 3,78 50,78 lod 2,5 4,5
Bourran2_2014_rEpiBC*_3P Qrob_Chr03 3 s_1A3B3X_1163 s_1DKGMO_450 23,04 4,92 41,12 lod 2,5668 7

0 Targeting