Protein : Qrob_P0556060.2 Q. robur

Protein Identifier  ? Qrob_P0556060.2 Organism . Name  Quercus robur
Score  86.2 Score Type  egn
Protein Description  (M=6) 3.2.1.45 - Glucosylceramidase. Code Enzyme  EC:3.2.1.45
Gene Prediction Quality  validated Protein length 

Sequence

Length: 940  
Kegg Orthology  K17108

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0 Synonyms

6 GO Terms

Identifier Name Description
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0004348 glucosylceramidase activity Catalysis of the reaction: D-glucosyl-N-acylsphingosine + H2O = D-glucose + N-acylsphingosine.
GO:0006665 sphingolipid metabolic process The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
GO:0006680 glucosylceramide catabolic process The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.

18 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|tcc:TCM_006124 1 939 + 939 Gaps:13 100.00 952 78.99 0.0 Non-lysosomal glucosylceramidase
blastp_kegg lcl|pmum:103318985 1 939 + 939 Gaps:13 100.00 952 79.62 0.0 non-lysosomal glucosylceramidase
blastp_kegg lcl|pper:PRUPE_ppa000954mg 1 939 + 939 Gaps:13 100.00 952 79.20 0.0 hypothetical protein
blastp_kegg lcl|pxb:103933391 1 937 + 937 Gaps:15 98.35 968 76.68 0.0 non-lysosomal glucosylceramidase-like
blastp_kegg lcl|rcu:RCOM_0618840 1 938 + 938 Gaps:14 99.79 952 77.68 0.0 hypothetical protein
blastp_kegg lcl|cit:102619857 1 939 + 939 Gaps:15 100.00 954 75.68 0.0 non-lysosomal glucosylceramidase-like
blastp_kegg lcl|pxb:103946388 1 937 + 937 Gaps:13 99.79 952 76.00 0.0 non-lysosomal glucosylceramidase-like
blastp_kegg lcl|vvi:100248921 9 937 + 929 Gaps:26 99.48 960 75.29 0.0 non-lysosomal glucosylceramidase-like
blastp_kegg lcl|cic:CICLE_v10000199mg 1 939 + 939 Gaps:17 100.00 926 76.46 0.0 hypothetical protein
blastp_kegg lcl|fve:101301209 9 937 + 929 Gaps:17 99.37 948 75.05 0.0 non-lysosomal glucosylceramidase-like
blastp_uniprot_sprot sp|Q9HCG7|GBA2_HUMAN 52 875 + 824 Gaps:105 84.03 927 42.88 0.0 Non-lysosomal glucosylceramidase OS Homo sapiens GN GBA2 PE 1 SV 2
blastp_uniprot_sprot sp|Q69ZF3|GBA2_MOUSE 52 875 + 824 Gaps:101 84.86 918 42.75 0.0 Non-lysosomal glucosylceramidase OS Mus musculus GN Gba2 PE 1 SV 2
blastp_uniprot_sprot sp|Q5M868|GBA2_RAT 52 875 + 824 Gaps:93 85.42 912 42.36 0.0 Non-lysosomal glucosylceramidase OS Rattus norvegicus GN Gba2 PE 2 SV 2
blastp_uniprot_sprot sp|Q7KT91|C3390_DROME 111 883 + 773 Gaps:113 80.80 948 37.60 3e-80 Non-lysosomal glucosylceramidase OS Drosophila melanogaster GN CG33090 PE 1 SV 1
rpsblast_cdd gnl|CDD|191062 517 879 + 363 Gaps:16 100.00 357 52.10 1e-148 pfam04685 DUF608 Protein of unknown function DUF608. This family represents a conserved region with a pankaryotic distribution in a number of uncharacterized proteins.
rpsblast_cdd gnl|CDD|34072 516 881 + 366 Gaps:26 52.15 721 34.84 6e-68 COG4354 COG4354 Predicted bile acid beta-glucosidase [Carbohydrate transport and metabolism].
rpsblast_cdd gnl|CDD|152650 96 398 + 303 Gaps:38 98.71 311 34.53 5e-61 pfam12215 GBA2_N beta-Glucocerebrosidase 2 N terminal. This domain is found in bacteria archaea and eukaryotes. This domain is typically between 320 to 354 amino acids in length. This domain is found associated with pfam04685. This domain is found in the protein beta-Glucocerebrosidase 2. It is found just after the extreme N terminus. This protein is located in the ER. The N terminal is thought to be the luminal domain while the C terminal is the cytosolic domain. The catalytic domain of GBA-2 is unknown.
rpsblast_kog gnl|CDD|37330 22 934 + 913 Gaps:81 98.07 879 58.35 0.0 KOG2119 KOG2119 KOG2119 Predicted bile acid beta-glucosidase [Carbohydrate transport and metabolism].

9 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 624 730 107 G3DSA:1.50.10.10 none none IPR012341
PANTHER 12 442 431 PTHR12654:SF3 none none none
PANTHER 490 938 449 PTHR12654:SF3 none none none
Pfam 96 400 305 PF12215 "KEGG:00511+3.2.1.45","KEGG:00600+3.2.1.45" beta-Glucocerebrosidase 2 N terminal IPR024462
PANTHER 12 442 431 PTHR12654 none none none
PANTHER 490 938 449 PTHR12654 none none none
Pfam 517 879 363 PF04685 none Protein of unknown function, DUF608 IPR006775
PIRSF 30 886 857 PIRSF028944 "KEGG:00511+3.2.1.45","KEGG:00600+3.2.1.45" none IPR014551
SUPERFAMILY 504 881 378 SSF48208 none none IPR008928

0 Localization

0 Qtllist

0 Targeting