Protein : Qrob_P0556050.2 Q. robur

Protein Identifier  ? Qrob_P0556050.2 Organism . Name  Quercus robur
Score  54.1 Score Type  egn
Protein Description  (M=6) 3.2.1.45 - Glucosylceramidase. Code Enzyme  EC:3.2.1.45
Gene Prediction Quality  validated Protein length 

Sequence

Length: 960  
Kegg Orthology  K17108

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0 Synonyms

6 GO Terms

Identifier Name Description
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0004348 glucosylceramidase activity Catalysis of the reaction: D-glucosyl-N-acylsphingosine + H2O = D-glucose + N-acylsphingosine.
GO:0006665 sphingolipid metabolic process The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
GO:0006680 glucosylceramide catabolic process The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.

18 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|tcc:TCM_006124 16 959 + 944 Gaps:44 100.00 952 75.74 0.0 Non-lysosomal glucosylceramidase
blastp_kegg lcl|pxb:103933391 11 957 + 947 Gaps:46 98.86 968 73.04 0.0 non-lysosomal glucosylceramidase-like
blastp_kegg lcl|pmum:103318985 16 959 + 944 Gaps:44 100.00 952 75.74 0.0 non-lysosomal glucosylceramidase
blastp_kegg lcl|pper:PRUPE_ppa000954mg 16 959 + 944 Gaps:44 100.00 952 75.63 0.0 hypothetical protein
blastp_kegg lcl|rcu:RCOM_0618840 16 958 + 943 Gaps:45 99.79 952 74.63 0.0 hypothetical protein
blastp_kegg lcl|pxb:103946388 16 957 + 942 Gaps:44 99.79 952 72.63 0.0 non-lysosomal glucosylceramidase-like
blastp_kegg lcl|cit:102619857 16 959 + 944 Gaps:46 100.00 954 72.54 0.0 non-lysosomal glucosylceramidase-like
blastp_kegg lcl|vvi:100248921 24 957 + 934 Gaps:57 99.48 960 72.15 0.0 non-lysosomal glucosylceramidase-like
blastp_kegg lcl|fve:101301209 24 957 + 934 Gaps:48 99.37 948 71.76 0.0 non-lysosomal glucosylceramidase-like
blastp_kegg lcl|cic:CICLE_v10000199mg 16 959 + 944 Gaps:48 100.00 926 73.22 0.0 hypothetical protein
blastp_uniprot_sprot sp|Q9HCG7|GBA2_HUMAN 113 895 + 783 Gaps:116 77.56 927 43.81 0.0 Non-lysosomal glucosylceramidase OS Homo sapiens GN GBA2 PE 1 SV 2
blastp_uniprot_sprot sp|Q69ZF3|GBA2_MOUSE 113 895 + 783 Gaps:108 78.32 918 43.25 5e-178 Non-lysosomal glucosylceramidase OS Mus musculus GN Gba2 PE 1 SV 2
blastp_uniprot_sprot sp|Q5M868|GBA2_RAT 113 895 + 783 Gaps:108 78.84 912 43.25 7e-178 Non-lysosomal glucosylceramidase OS Rattus norvegicus GN Gba2 PE 2 SV 2
blastp_uniprot_sprot sp|Q7KT91|C3390_DROME 113 903 + 791 Gaps:131 80.80 948 37.86 1e-78 Non-lysosomal glucosylceramidase OS Drosophila melanogaster GN CG33090 PE 1 SV 1
rpsblast_cdd gnl|CDD|191062 537 899 + 363 Gaps:16 100.00 357 52.38 1e-145 pfam04685 DUF608 Protein of unknown function DUF608. This family represents a conserved region with a pankaryotic distribution in a number of uncharacterized proteins.
rpsblast_cdd gnl|CDD|34072 536 901 + 366 Gaps:28 52.15 721 35.37 3e-66 COG4354 COG4354 Predicted bile acid beta-glucosidase [Carbohydrate transport and metabolism].
rpsblast_cdd gnl|CDD|152650 106 418 + 313 Gaps:56 96.14 311 33.11 2e-51 pfam12215 GBA2_N beta-Glucocerebrosidase 2 N terminal. This domain is found in bacteria archaea and eukaryotes. This domain is typically between 320 to 354 amino acids in length. This domain is found associated with pfam04685. This domain is found in the protein beta-Glucocerebrosidase 2. It is found just after the extreme N terminus. This protein is located in the ER. The N terminal is thought to be the luminal domain while the C terminal is the cytosolic domain. The catalytic domain of GBA-2 is unknown.
rpsblast_kog gnl|CDD|37330 37 954 + 918 Gaps:110 98.07 879 56.03 0.0 KOG2119 KOG2119 KOG2119 Predicted bile acid beta-glucosidase [Carbohydrate transport and metabolism].

11 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Pfam 106 420 315 PF12215 "KEGG:00511+3.2.1.45","KEGG:00600+3.2.1.45" beta-Glucocerebrosidase 2 N terminal IPR024462
Gene3D 638 750 113 G3DSA:1.50.10.10 none none IPR012341
PIRSF 60 906 847 PIRSF028944 "KEGG:00511+3.2.1.45","KEGG:00600+3.2.1.45" none IPR014551
PANTHER 27 317 291 PTHR12654:SF3 none none none
PANTHER 336 462 127 PTHR12654:SF3 none none none
PANTHER 510 958 449 PTHR12654:SF3 none none none
PANTHER 27 317 291 PTHR12654 none none none
PANTHER 336 462 127 PTHR12654 none none none
PANTHER 510 958 449 PTHR12654 none none none
Pfam 537 899 363 PF04685 none Protein of unknown function, DUF608 IPR006775
SUPERFAMILY 515 901 387 SSF48208 none none IPR008928

0 Localization

0 Qtllist

0 Targeting