Protein : Qrob_P0488980.2 Q. robur

Protein Identifier  ? Qrob_P0488980.2 Organism . Name  Quercus robur
Score  36.0 Score Type  egn
Protein Description  (M=2) PTHR12013 - SIGNAL RECOGNITION PARTICLE 14 KD PROTEIN Gene Prediction Quality  validated
Protein length 

Sequence

Length: 257  

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0 Synonyms

5 GO Terms

Identifier Name Description
GO:0006614 SRP-dependent cotranslational protein targeting to membrane The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.
GO:0008312 7S RNA binding Interacting selectively and non-covalently with 7S RNA, the RNA component of the signal recognition particle (SRP).
GO:0048500 signal recognition particle A complex of protein and RNA which facilitates translocation of proteins across membranes.
GO:0005786 signal recognition particle, endoplasmic reticulum targeting A ribonucleoprotein particle of 325 kDa composed of a 7S (300 nucleotide) RNA molecule and a complex of six different polypeptides. This binds both to the N-terminal signal peptide for proteins destined for the endoplasmic reticulum as they emerge from the large ribosomal subunit and also to the ribosome. This binding arrests further translation thereby preventing the proteins from being released into the cytosol. The SRP-ribosome complex then diffuses to the endoplasmic reticulum where it is bound to the signal recognition particle receptor, which allows resumption of protein synthesis and facilitates the passage of the growing polypeptide chain through the translocon. Through a process involving GTP hydrolysis, the SRP-SRP receptor complex dissociates and SRP returns to the cytosol. Of the six polypeptides of SRP the 54 kDa subunit (SRP54) is the central player. It contains an N-terminal GTPase domain and a C-terminal domain that binds directly to the signal peptide and the SRP RNA. Examples of this component are found in Mus musculus, Saccharomyces cerevisiae and Arabidopsis thaliana.
GO:0030942 endoplasmic reticulum signal peptide binding Interacting selectively and non-covalently with an endoplasmic reticulum signal peptide, a specific peptide sequence that acts as a signal to localize the protein within the endoplasmic reticulum.

27 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pop:POPTR_0013s12890g 138 252 + 115 none 95.04 121 86.09 5e-57 signal recognition particle 14 kDa family protein
blastp_kegg lcl|pvu:PHAVU_011G004600g 138 255 + 118 none 98.33 120 84.75 2e-55 hypothetical protein
blastp_kegg lcl|gmx:100526909 138 255 + 118 none 98.33 120 83.90 3e-55 uncharacterized LOC100526909
blastp_kegg lcl|mtr:MTR_040s0033 138 255 + 118 none 98.33 120 83.90 4e-55 Signal recognition particle 14 kDa protein
blastp_kegg lcl|cmo:103487869 138 255 + 118 Gaps:3 97.46 118 89.57 5e-55 signal recognition particle 14 kDa protein
blastp_kegg lcl|csv:101228792 138 255 + 118 Gaps:3 97.46 118 89.57 5e-55 signal recognition particle 14 kDa protein-like
blastp_kegg lcl|csv:101205402 138 255 + 118 Gaps:3 97.46 118 89.57 5e-55 signal recognition particle 14 kDa protein-like
blastp_kegg lcl|csv:101223050 138 255 + 118 Gaps:3 97.46 118 89.57 5e-55 signal recognition particle 14 kDa protein-like
blastp_kegg lcl|cam:101503551 138 255 + 118 none 98.33 120 84.75 6e-55 signal recognition particle 14 kDa protein-like
blastp_kegg lcl|tcc:TCM_019902 138 256 + 119 Gaps:1 99.16 119 85.59 4e-54 Signal recognition particle 14 kDa protein
blastp_pdb 1ry1_D 138 229 + 92 Gaps:1 87.74 106 43.01 3e-17 mol:protein length:106 PROTEIN (Signal recognition particle 14 kDa p
blastp_pdb 1e8s_B 138 229 + 92 Gaps:1 87.74 106 43.01 3e-17 mol:protein length:106 SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN
blastp_pdb 1e8o_D 138 229 + 92 Gaps:1 87.74 106 43.01 3e-17 mol:protein length:106 SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN
blastp_pdb 1e8o_B 138 229 + 92 Gaps:1 87.74 106 43.01 3e-17 mol:protein length:106 SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN
blastp_pdb 1914_A 138 229 + 92 Gaps:1 40.09 232 41.94 7e-16 mol:protein length:232 SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTE
blastp_uniprot_sprot sp|O04421|SRP14_ARATH 138 247 + 110 none 90.91 121 85.45 1e-53 Signal recognition particle 14 kDa protein OS Arabidopsis thaliana GN SRP14 PE 2 SV 2
blastp_uniprot_sprot sp|O04433|SRP14_ORYSJ 138 245 + 108 none 81.82 132 67.59 2e-38 Signal recognition particle 14 kDa protein OS Oryza sativa subsp. japonica GN SRP14 PE 2 SV 1
blastp_uniprot_sprot sp|Q4R5C7|SRP14_MACFA 138 237 + 100 Gaps:1 70.14 144 44.55 9e-20 Signal recognition particle 14 kDa protein OS Macaca fascicularis GN SRP14 PE 2 SV 1
blastp_uniprot_sprot sp|Q5RBX7|SRP14_PONAB 138 236 + 99 Gaps:1 73.53 136 44.00 2e-19 Signal recognition particle 14 kDa protein OS Pongo abelii GN SRP14 PE 2 SV 1
blastp_uniprot_sprot sp|P37108|SRP14_HUMAN 138 236 + 99 Gaps:1 73.53 136 44.00 2e-19 Signal recognition particle 14 kDa protein OS Homo sapiens GN SRP14 PE 1 SV 2
blastp_uniprot_sprot sp|P16254|SRP14_MOUSE 138 229 + 92 Gaps:1 84.55 110 41.94 2e-16 Signal recognition particle 14 kDa protein OS Mus musculus GN Srp14 PE 1 SV 1
blastp_uniprot_sprot sp|P16255|SRP14_CANFA 138 229 + 92 Gaps:1 84.55 110 41.94 1e-15 Signal recognition particle 14 kDa protein OS Canis familiaris GN SRP14 PE 1 SV 2
blastp_uniprot_sprot sp|A6QQL9|SRP14_BOVIN 138 229 + 92 Gaps:1 84.55 110 41.94 2e-15 Signal recognition particle 14 kDa protein OS Bos taurus GN SRP14 PE 3 SV 1
blastp_uniprot_sprot sp|Q556L1|SRP14_DICDI 138 230 + 93 Gaps:3 78.05 123 37.50 3e-11 Signal recognition particle 14 kDa protein OS Dictyostelium discoideum GN srp14-1 PE 3 SV 1
blastp_uniprot_sprot sp|O16927|SRP14_CAEEL 143 234 + 92 Gaps:5 80.17 116 37.63 1e-05 Signal recognition particle 14 kDa protein OS Caenorhabditis elegans GN F25G6.8 PE 3 SV 1
rpsblast_cdd gnl|CDD|202191 140 229 + 90 Gaps:1 100.00 91 48.35 5e-24 pfam02290 SRP14 Signal recognition particle 14kD protein. The signal recognition particle (SRP) is a multimeric protein involved in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP14 and SRP9 form a complex essential for SRP RNA binding.
rpsblast_kog gnl|CDD|36972 138 248 + 111 Gaps:3 98.28 116 48.25 4e-25 KOG1761 KOG1761 KOG1761 Signal recognition particle subunit Srp14 [Intracellular trafficking secretion and vesicular transport].

12 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 138 247 110 G3DSA:3.30.720.10 "Reactome:REACT_15380" none IPR009018
Phobius 76 80 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 54 75 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 1 19 19 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 20 42 23 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 43 53 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 99 256 158 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
ProDom 138 206 69 PD009170 none RECOGNITION SIGNAL PARTICLE SRP14 RNA-BINDING ALU RNA 14KD 14KDA CDNA IPR003210
SUPERFAMILY 138 232 95 SSF54762 "Reactome:REACT_15380" none IPR009018
Phobius 81 98 18 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PANTHER 138 239 102 PTHR12013 none none IPR003210
Pfam 140 229 90 PF02290 none Signal recognition particle 14kD protein IPR003210

2 Localization

Analysis Start End Length
TMHMM 53 75 22
TMHMM 21 43 22

0 Qtllist

0 Targeting