Protein : Qrob_P0409500.2 Q. robur
Protein Identifier  ? Qrob_P0409500.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) PTHR10110//PTHR10110:SF95 - SODIUM/HYDROGEN EXCHANGER // SUBFAMILY NOT NAMED Gene Prediction Quality  validated
Protein length 

Sequence

Length: 311  
Kegg Orthology  K14724
Paste the following link
Lists
This Protein isn't in any lists. Upload a list.

Sequence Feature Displayer

Protein Sequence Displayer

J Browse Displayer

0 Synonyms

7 GO Terms

Identifier Name Description
GO:0055085 transmembrane transport The process in which a solute is transported from one side of a membrane to the other.
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0006814 sodium ion transport The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006812 cation transport The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015299 solute:proton antiporter activity Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out).
GO:0006885 regulation of pH Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.
GO:0015385 sodium:proton antiporter activity Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).

26 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|crb:CARUB_v10022249mg 6 302 + 297 Gaps:81 76.39 487 57.26 7e-119 hypothetical protein
blastp_kegg lcl|sbi:SORBI_02g028040 2 302 + 301 Gaps:82 75.84 476 54.02 4e-105 SORBIDRAFT_02g028040 Sb02g028040 hypothetical protein
blastp_kegg lcl|brp:103830473 6 302 + 297 Gaps:38 67.10 535 72.98 3e-104 sodium/hydrogen exchanger 6-like
blastp_kegg lcl|aly:ARALYDRAFT_677531 6 302 + 297 Gaps:38 66.98 536 73.54 5e-104 hypothetical protein
blastp_kegg lcl|ath:AT1G79610 6 302 + 297 Gaps:38 67.10 535 73.26 2e-103 NHX6 sodium/hydrogen exchanger 6
blastp_kegg lcl|brp:103832431 6 302 + 297 Gaps:38 66.36 541 72.14 3e-103 sodium/hydrogen exchanger 6
blastp_kegg lcl|eus:EUTSA_v10018385mg 6 302 + 297 Gaps:38 67.23 534 72.70 2e-102 hypothetical protein
blastp_kegg lcl|mdm:103438310 6 233 + 228 Gaps:5 73.77 305 78.67 6e-101 sodium/hydrogen exchanger 6
blastp_kegg lcl|dosa:Os09t0286400-01 19 302 + 284 Gaps:57 76.45 535 64.79 9e-101 Os09g0286400 Sodium/hydrogen exchanger subfamily protein.
blastp_kegg lcl|osa:4346626 19 302 + 284 Gaps:57 76.45 535 64.79 9e-101 Os09g0286400
blastp_uniprot_sprot sp|Q8RWU6|NHX6_ARATH 6 302 + 297 Gaps:38 67.10 535 73.26 6e-105 Sodium/hydrogen exchanger 6 OS Arabidopsis thaliana GN NHX6 PE 1 SV 3
blastp_uniprot_sprot sp|Q8S396|NHX5_ARATH 7 293 + 287 Gaps:37 67.18 521 67.71 7e-88 Sodium/hydrogen exchanger 5 OS Arabidopsis thaliana GN NHX5 PE 2 SV 2
blastp_uniprot_sprot sp|Q5ZJ75|SL9A8_CHICK 15 225 + 211 Gaps:16 38.15 574 35.16 2e-29 Sodium/hydrogen exchanger 8 OS Gallus gallus PE 2 SV 1
blastp_uniprot_sprot sp|Q4R8V4|SL9A8_MACFA 15 225 + 211 Gaps:16 40.41 542 35.62 6e-29 Sodium/hydrogen exchanger 8 OS Macaca fascicularis GN SLC9A8 PE 2 SV 1
blastp_uniprot_sprot sp|Q9Y2E8|SL9A8_HUMAN 15 225 + 211 Gaps:16 37.69 581 35.62 9e-29 Sodium/hydrogen exchanger 8 OS Homo sapiens GN SLC9A8 PE 1 SV 4
blastp_uniprot_sprot sp|Q8R4D1|SL9A8_MOUSE 15 225 + 211 Gaps:16 38.02 576 34.70 4e-28 Sodium/hydrogen exchanger 8 OS Mus musculus GN Slc9a8 PE 2 SV 1
blastp_uniprot_sprot sp|Q4L208|SL9A8_RAT 8 225 + 218 Gaps:20 40.00 575 33.91 4e-28 Sodium/hydrogen exchanger 8 OS Rattus norvegicus GN Slc9a8 PE 2 SV 1
blastp_uniprot_sprot sp|O13726|YDO6_SCHPO 43 200 + 158 Gaps:5 27.34 567 43.23 3e-25 Uncharacterized Na(+)/H(+) antiporter C15A10.06 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN SPAC15A10.06 PE 1 SV 3
blastp_uniprot_sprot sp|Q92581|SL9A6_HUMAN 47 200 + 154 Gaps:29 25.26 669 43.79 5e-24 Sodium/hydrogen exchanger 6 OS Homo sapiens GN SLC9A6 PE 1 SV 2
blastp_uniprot_sprot sp|Q8IVB4|SL9A9_HUMAN 22 302 + 281 Gaps:96 56.43 645 32.42 6e-24 Sodium/hydrogen exchanger 9 OS Homo sapiens GN SLC9A9 PE 1 SV 1
rpsblast_cdd gnl|CDD|162063 54 302 + 249 Gaps:49 49.02 559 36.86 2e-25 TIGR00840 b_cpa1 sodium/hydrogen exchanger 3. The Monovalent Cation:Proton Antiporter-1 (CPA1) Family (TC 2.A.36)The CPA1 family is a large family of proteins derived from Gram-positive and Gram-negative bacteria blue green bacteria yeast plants and animals.Transporters from eukaryotes have been functionally characterized and all of these catalyze Na+:H+ exchange. Their primary physiological functions may be in(1) cytoplasmic pH regulation extruding the H+ generated during metabolism and (2) salt tolerance (in plants) due to Na+ uptake into vacuoles.This Hmm is specific for the eukaryotic members members of this family.
rpsblast_cdd gnl|CDD|201544 33 201 + 169 Gaps:23 41.08 370 36.18 1e-13 pfam00999 Na_H_Exchanger Sodium/hydrogen exchanger family. Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family.
rpsblast_cdd gnl|CDD|30375 29 200 + 172 Gaps:14 36.83 429 27.22 2e-12 COG0025 NhaP NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].
rpsblast_cdd gnl|CDD|129911 33 199 + 167 Gaps:23 28.19 525 31.08 3e-11 TIGR00831 a_cpa1 Na+/H+ antiporter bacterial form. The Monovalent Cation:Proton Antiporter-1 (CPA1) Family (TC 2.A.36) The CPA1 family is a large family of proteins derived from Gram-positive and Gram-negative bacteria blue green bacteria yeast plants and animals. Transporters from eukaryotes have been functionally characterized and all of these catalyze Na+:H+ exchange. Their primary physiological functions may be in (1) cytoplasmic pH regulation extruding the H+ generated during metabolism and (2) salt tolerance (in plants) due to Na+ uptake into vacuoles. This Hmm is specific for the bacterial members of this family.
rpsblast_kog gnl|CDD|37176 11 302 + 292 Gaps:65 73.22 575 41.57 3e-48 KOG1965 KOG1965 KOG1965 Sodium/hydrogen exchanger protein [Inorganic ion transport and metabolism].
rpsblast_kog gnl|CDD|37177 54 200 + 147 Gaps:14 21.04 670 41.13 4e-26 KOG1966 KOG1966 KOG1966 Sodium/hydrogen exchanger protein [Inorganic ion transport and metabolism].

20 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Phobius 290 309 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 91 112 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PANTHER 11 302 292 PTHR10110:SF95 none none none
Phobius 113 118 6 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 168 259 92 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 24 46 23 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 119 143 25 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PRINTS 90 101 12 PR01084 "Reactome:REACT_15518" Na+/H+ exchanger signature IPR004709
PRINTS 162 172 11 PR01084 "Reactome:REACT_15518" Na+/H+ exchanger signature IPR004709
Phobius 53 71 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 47 52 6 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 149 167 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 1 23 23 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 72 90 19 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 260 278 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 279 289 11 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
PANTHER 11 302 292 PTHR10110 "Reactome:REACT_15518";signature_desc=SODIUM/HYDROGEN EXCHANGER none IPR018422
Phobius 144 148 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Pfam 35 207 173 PF00999 none Sodium/hydrogen exchanger family IPR006153
Phobius 310 310 1 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none

7 Localization

Analysis Start End Length
TMHMM 225 247 22
TMHMM 287 309 22
TMHMM 260 277 17
TMHMM 53 75 22
TMHMM 119 141 22
TMHMM 90 112 22
TMHMM 24 46 22

0 Qtllist

0 Targeting