Protein : Qrob_P0400610.2 Q. robur
Protein Identifier  ? Qrob_P0400610.2 Organism . Name  Quercus robur
Score  0.0 Score Type  egn
Protein Description  (M=7) PTHR10169:SF38 - DNA TOPOISOMERASE 2 (PTHR10169:SF38) Code Enzyme  EC:5.99.1.3
Gene Prediction Quality  validated Protein length 

Sequence

Length: 167  
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0005524 ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
GO:0006265 DNA topological change The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.

35 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|cmo:103500322 31 113 + 83 none 5.57 1490 80.72 1e-38 DNA topoisomerase 2
blastp_kegg lcl|mdm:103438420 15 113 + 99 none 6.77 1462 67.68 8e-38 DNA topoisomerase 2-like
blastp_kegg lcl|pmum:103330635 15 113 + 99 none 6.73 1471 67.68 9e-38 DNA topoisomerase 2
blastp_kegg lcl|pper:PRUPE_ppa000202mg 15 113 + 99 none 6.73 1471 67.68 1e-37 hypothetical protein
blastp_kegg lcl|mdm:103409964 15 113 + 99 none 6.90 1435 67.68 1e-37 DNA topoisomerase 2-like
blastp_kegg lcl|pop:POPTR_0009s06380g 15 113 + 99 none 6.68 1482 68.69 1e-37 POPTRDRAFT_557797 DNA topoisomerase family protein
blastp_kegg lcl|mdm:103407514 15 113 + 99 none 13.56 730 67.68 2e-37 DNA topoisomerase 2-like
blastp_kegg lcl|fve:101308524 15 113 + 99 none 6.74 1469 66.67 2e-37 DNA topoisomerase 2-like
blastp_kegg lcl|vvi:100253371 31 113 + 83 none 5.57 1489 77.11 3e-37 DNA topoisomerase 2-like
blastp_kegg lcl|csv:101215950 41 113 + 73 none 5.00 1459 86.30 4e-37 DNA topoisomerase 2-like
blastp_pdb 3qx3_B 31 113 + 83 Gaps:3 9.96 803 58.75 2e-21 mol:protein length:803 DNA topoisomerase 2-beta
blastp_pdb 3qx3_A 31 113 + 83 Gaps:3 9.96 803 58.75 2e-21 mol:protein length:803 DNA topoisomerase 2-beta
blastp_pdb 3l4k_A 31 100 + 70 Gaps:2 9.51 757 52.78 7e-19 mol:protein length:757 DNA topoisomerase 2
blastp_pdb 3l4j_A 31 100 + 70 Gaps:2 9.51 757 52.78 7e-19 mol:protein length:757 DNA topoisomerase 2
blastp_pdb 2rgr_A 31 100 + 70 Gaps:2 9.49 759 51.39 2e-17 mol:protein length:759 DNA topoisomerase 2
blastp_pdb 1bjt_A 31 100 + 70 Gaps:2 9.08 793 51.39 2e-17 mol:protein length:793 TOPOISOMERASE II
blastp_pdb 1bgw_A 31 100 + 70 Gaps:2 9.08 793 51.39 2e-17 mol:protein length:793 TOPOISOMERASE
blastp_uniprot_sprot sp|P30182|TOP2_ARATH 31 113 + 83 Gaps:3 5.70 1473 71.43 8e-34 DNA topoisomerase 2 OS Arabidopsis thaliana GN TOP2 PE 2 SV 2
blastp_uniprot_sprot sp|O24308|TOP2_PEA 15 113 + 99 none 6.77 1462 57.58 5e-32 DNA topoisomerase 2 OS Pisum sativum GN TOP2 PE 2 SV 1
blastp_uniprot_sprot sp|P08096|TOP2_SCHPO 31 113 + 83 Gaps:2 5.45 1485 58.02 3e-24 DNA topoisomerase 2 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN top2 PE 1 SV 2
blastp_uniprot_sprot sp|Q55BP5|TOP2_DICDI 31 113 + 83 Gaps:3 5.26 1521 55.00 1e-23 Probable DNA topoisomerase 2 OS Dictyostelium discoideum GN top2 PE 3 SV 1
blastp_uniprot_sprot sp|Q9Y8G8|TOP2_PENCH 16 113 + 98 Gaps:5 6.36 1587 54.46 6e-23 DNA topoisomerase 2 OS Penicillium chrysogenum GN TOP2 PE 3 SV 1
blastp_uniprot_sprot sp|P15348|TOP2_DROME 31 113 + 83 Gaps:3 5.53 1447 61.25 2e-22 DNA topoisomerase 2 OS Drosophila melanogaster GN Top2 PE 1 SV 1
blastp_uniprot_sprot sp|P41001|TOP2_PLAFK 31 113 + 83 Gaps:3 5.72 1398 57.50 1e-21 DNA topoisomerase 2 OS Plasmodium falciparum (isolate K1 / Thailand) GN TOP2 PE 3 SV 1
blastp_uniprot_sprot sp|O16140|TOP2_BOMMO 31 113 + 83 Gaps:3 5.17 1547 58.75 5e-21 DNA topoisomerase 2 OS Bombyx mori GN TOP2 PE 2 SV 1
blastp_uniprot_sprot sp|Q64511|TOP2B_MOUSE 31 113 + 83 Gaps:3 4.96 1612 58.75 1e-20 DNA topoisomerase 2-beta OS Mus musculus GN Top2b PE 1 SV 2
blastp_uniprot_sprot sp|Q02880|TOP2B_HUMAN 31 113 + 83 Gaps:3 4.92 1626 58.75 1e-20 DNA topoisomerase 2-beta OS Homo sapiens GN TOP2B PE 1 SV 3
rpsblast_cdd gnl|CDD|178775 31 113 + 83 none 5.67 1465 72.29 1e-42 PLN03237 PLN03237 DNA topoisomerase 2 Provisional.
rpsblast_cdd gnl|CDD|178674 31 113 + 83 Gaps:1 7.22 1135 68.29 1e-36 PLN03128 PLN03128 DNA topoisomerase 2 Provisional.
rpsblast_cdd gnl|CDD|185451 31 113 + 83 Gaps:2 5.84 1388 61.73 5e-31 PTZ00108 PTZ00108 DNA topoisomerase 2-like protein Provisional.

14 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Phobius 1 10 10 SIGNAL_PEPTIDE_N_REGION none N-terminal region of a signal peptide. none
SUPERFAMILY 22 113 92 SSF56719 none none IPR013760
Gene3D 31 103 73 G3DSA:3.40.50.670 none none IPR013759
Phobius 1 27 27 SIGNAL_PEPTIDE none Signal peptide region none
Phobius 11 22 12 SIGNAL_PEPTIDE_H_REGION none Hydrophobic region of a signal peptide. none
PANTHER 41 113 73 PTHR10169 none none none
PRINTS 69 80 12 PR01158 none Topoisomerase II signature IPR001154
PRINTS 48 63 16 PR01158 none Topoisomerase II signature IPR001154
Phobius 28 166 139 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
PRINTS 68 80 13 PR00418 none DNA topoisomerase II family signature IPR001241
PRINTS 29 45 17 PR00418 none DNA topoisomerase II family signature IPR001241
PRINTS 47 64 18 PR00418 none DNA topoisomerase II family signature IPR001241
PANTHER 41 113 73 PTHR10169:SF38 none none none
Phobius 23 27 5 SIGNAL_PEPTIDE_C_REGION none C-terminal region of a signal peptide. none

2 Localization

Analysis Start End Length
TMHMM 7 29 22
SignalP_EUK 1 27 26

2 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2014_rEpiBC_3P Qrob_Chr05 5 s_2GDU0O_517 s_1BT8O3_239 25,81 0 55,45 lod 2,2101 5,5

0 Targeting