Protein : Qrob_P0357750.2 Q. robur
Protein Identifier  ? Qrob_P0357750.2 Organism . Name  Quercus robur
Score  0.0 Score Type  egn
Protein Description  (M=20) K00025 - malate dehydrogenase [EC:1.1.1.37] Code Enzyme  EC:1.1.1.37
Gene Prediction Quality  validated Protein length 

Sequence

Length: 346  
Kegg Orthology  K00025
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0 Synonyms

8 GO Terms

Identifier Name Description
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0005975 carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
GO:0006108 malate metabolic process The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
GO:0016615 malate dehydrogenase activity Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate.
GO:0019752 carboxylic acid metabolic process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).

43 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|csv:101221189 1 345 + 345 Gaps:32 97.53 364 72.39 4e-174 malate dehydrogenase cytoplasmic-like
blastp_kegg lcl|cmo:103483128 1 345 + 345 Gaps:32 97.53 364 72.39 5e-174 malate dehydrogenase cytoplasmic-like
blastp_kegg lcl|cit:102615934 3 345 + 343 Gaps:32 96.45 366 70.82 1e-169 malate dehydrogenase cytoplasmic-like
blastp_kegg lcl|pxb:103953311 4 345 + 342 Gaps:32 93.62 376 71.02 2e-168 malate dehydrogenase-like
blastp_kegg lcl|mdm:103435358 4 345 + 342 Gaps:32 93.62 376 71.02 1e-167 malate dehydrogenase-like
blastp_kegg lcl|pxb:103932637 4 345 + 342 Gaps:34 93.62 376 69.32 2e-166 malate dehydrogenase-like
blastp_kegg lcl|pxb:103932290 4 345 + 342 Gaps:32 93.62 376 71.31 8e-166 malate dehydrogenase-like
blastp_kegg lcl|tcc:TCM_005626 2 345 + 344 Gaps:33 88.09 403 69.30 2e-162 Lactate/malate dehydrogenase family protein isoform 1
blastp_kegg lcl|gmx:100783188 5 345 + 341 Gaps:32 94.10 373 67.24 2e-160 malate dehydrogenase cytoplasmic-like
blastp_kegg lcl|cic:CICLE_v10021075mg 33 345 + 313 Gaps:32 97.29 332 73.07 1e-159 hypothetical protein
blastp_pdb 5mdh_B 36 345 + 310 Gaps:33 96.40 333 52.02 3e-99 mol:protein length:333 MALATE DEHYDROGENASE
blastp_pdb 5mdh_A 36 345 + 310 Gaps:33 96.40 333 52.02 3e-99 mol:protein length:333 MALATE DEHYDROGENASE
blastp_pdb 4mdh_B 36 345 + 310 Gaps:33 96.11 334 52.02 3e-99 mol:protein length:334 CYTOPLASMIC MALATE DEHYDROGENASE
blastp_pdb 4mdh_A 36 345 + 310 Gaps:33 96.11 334 52.02 3e-99 mol:protein length:334 CYTOPLASMIC MALATE DEHYDROGENASE
blastp_pdb 2cvq_B 35 345 + 311 Gaps:37 96.64 327 46.84 9e-80 mol:protein length:327 Malate dehydrogenase
blastp_pdb 2cvq_A 35 345 + 311 Gaps:37 96.64 327 46.84 9e-80 mol:protein length:327 Malate dehydrogenase
blastp_pdb 1y7t_B 35 345 + 311 Gaps:37 96.64 327 46.84 9e-80 mol:protein length:327 Malate dehydrogenase
blastp_pdb 1y7t_A 35 345 + 311 Gaps:37 96.64 327 46.84 9e-80 mol:protein length:327 Malate dehydrogenase
blastp_pdb 1iz9_B 35 345 + 311 Gaps:37 96.64 327 46.84 9e-80 mol:protein length:327 MALATE DEHYDROGENASE
blastp_pdb 1iz9_A 35 345 + 311 Gaps:37 96.64 327 46.84 9e-80 mol:protein length:327 MALATE DEHYDROGENASE
blastp_uniprot_sprot sp|Q08062|MDHC_MAIZE 33 345 + 313 Gaps:32 97.29 332 70.59 2e-153 Malate dehydrogenase cytoplasmic OS Zea mays PE 1 SV 2
blastp_uniprot_sprot sp|Q7XDC8|MDHC_ORYSJ 33 345 + 313 Gaps:32 97.29 332 69.97 2e-153 Malate dehydrogenase cytoplasmic OS Oryza sativa subsp. japonica GN Os10g0478200 PE 1 SV 3
blastp_uniprot_sprot sp|O48905|MDHC_MEDSA 33 345 + 313 Gaps:32 97.29 332 68.73 7e-151 Malate dehydrogenase cytoplasmic OS Medicago sativa GN CMDH PE 1 SV 1
blastp_uniprot_sprot sp|Q9FSF0|MDH_TOBAC 33 345 + 313 Gaps:32 97.29 332 69.04 8e-150 Malate dehydrogenase OS Nicotiana tabacum GN MD1 PE 1 SV 1
blastp_uniprot_sprot sp|P57106|MDHC2_ARATH 33 345 + 313 Gaps:32 97.29 332 68.73 4e-148 Malate dehydrogenase cytoplasmic 2 OS Arabidopsis thaliana GN At5g43330 PE 2 SV 1
blastp_uniprot_sprot sp|O24047|MDHC_MESCR 33 345 + 313 Gaps:32 97.29 332 69.04 2e-147 Malate dehydrogenase cytoplasmic OS Mesembryanthemum crystallinum GN MDH PE 2 SV 1
blastp_uniprot_sprot sp|P93819|MDHC1_ARATH 33 345 + 313 Gaps:32 97.29 332 68.73 2e-147 Malate dehydrogenase cytoplasmic 1 OS Arabidopsis thaliana GN At1g04410 PE 1 SV 2
blastp_uniprot_sprot sp|Q9SML8|MDHC_BETVU 33 345 + 313 Gaps:32 97.29 332 67.49 3e-144 Malate dehydrogenase cytoplasmic OS Beta vulgaris GN NR1 PE 1 SV 1
blastp_uniprot_sprot sp|O88989|MDHC_RAT 36 345 + 310 Gaps:33 96.11 334 52.34 2e-100 Malate dehydrogenase cytoplasmic OS Rattus norvegicus GN Mdh1 PE 1 SV 3
blastp_uniprot_sprot sp|P14152|MDHC_MOUSE 36 345 + 310 Gaps:33 96.11 334 52.34 3e-100 Malate dehydrogenase cytoplasmic OS Mus musculus GN Mdh1 PE 1 SV 3

17 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 35 345 311 PTHR23382 "KEGG:00020+1.1.1.37","KEGG:00270+1.1.1.37","KEGG:00620+1.1.1.37","KEGG:00630+1.1.1.37","KEGG:00680+1.1.1.37","KEGG:00710+1.1.1.37","KEGG:00720+1.1.1.37","MetaCyc:PWY-1622","MetaCyc:PWY-5392","MetaCyc:PWY-561","MetaCyc:PWY-5690","MetaCyc:PWY-5913","MetaCyc:PWY-6728","MetaCyc:PWY-6969","MetaCyc:PWY-7115","MetaCyc:PWY-7383";signature_desc=MALATE DEHYDROGENASE none IPR010945
Gene3D 35 195 161 G3DSA:3.40.50.720 none none IPR016040
Phobius 6 28 23 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
ProSitePatterns 196 208 13 PS00068 "KEGG:00020+1.1.1.37","KEGG:00270+1.1.1.37","KEGG:00620+1.1.1.37","KEGG:00630+1.1.1.37","KEGG:00680+1.1.1.37","KEGG:00710+1.1.1.37","KEGG:00720+1.1.1.37","MetaCyc:PWY-1622","MetaCyc:PWY-5392","MetaCyc:PWY-561","MetaCyc:PWY-5690","MetaCyc:PWY-5913","MetaCyc:PWY-6728","MetaCyc:PWY-6969","MetaCyc:PWY-7115","MetaCyc:PWY-7383","Reactome:REACT_474" Malate dehydrogenase active site signature. IPR001252
Phobius 60 345 286 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Gene3D 290 345 56 G3DSA:3.90.110.10 none none IPR015955
Gene3D 196 289 94 G3DSA:3.90.110.10 none none IPR015955
Phobius 1 5 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
SUPERFAMILY 197 345 149 SSF56327 none none IPR015955
Phobius 29 39 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
TIGRFAM 36 345 310 TIGR01759 "KEGG:00020+1.1.1.37","KEGG:00270+1.1.1.37","KEGG:00620+1.1.1.37","KEGG:00630+1.1.1.37","KEGG:00680+1.1.1.37","KEGG:00710+1.1.1.37","KEGG:00720+1.1.1.37","MetaCyc:PWY-1622","MetaCyc:PWY-5392","MetaCyc:PWY-561","MetaCyc:PWY-5690","MetaCyc:PWY-5913","MetaCyc:PWY-6728","MetaCyc:PWY-6969","MetaCyc:PWY-7115","MetaCyc:PWY-7383" MalateDH-SF1: malate dehydrogenase IPR010945
Pfam 289 343 55 PF02866 none lactate/malate dehydrogenase, alpha/beta C-terminal domain IPR022383
Pfam 197 288 92 PF02866 none lactate/malate dehydrogenase, alpha/beta C-terminal domain IPR022383
Pfam 38 192 155 PF00056 none lactate/malate dehydrogenase, NAD binding domain IPR001236
Phobius 40 59 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PIRSF 34 345 312 PIRSF000102 none none IPR001557
SUPERFAMILY 27 195 169 SSF51735 none none none

2 Localization

Analysis Start End Length
TMHMM 38 60 22
TMHMM 4 26 22

5 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2015_nEpis_3P Qrob_Chr12 12 s_1AOES6_1466 s_1B0DDG_1094 28,97 28,55 30,1 lod 3.6 8.4
Bourran2_2014_nP_A4 Qrob_Chr11 11 s_1B58GB_1413 s_1A5BYY_1671 11,15 0 42,38 lod 1,8913 4,5
Bourran2_2002_QTL16_peak_Bud_burst_A4 Qrob_Chr11 11 s_A9OIA_166 s_1C6WBF_114 21,23 2,83 42,83 lod 5,1 7,2
Bourran2_2015_nSeqBC_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 26,06 25,47 27,72 lod 3.6 7.1
Champenoux_2015_nSecLBD_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 25,78 25,47 27,72 lod 6.3 16.6

0 Targeting