Protein : Qrob_P0326790.2 Q. robur

Protein Identifier  ? Qrob_P0326790.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=5) K00600 - glycine hydroxymethyltransferase [EC:2.1.2.1] Code Enzyme  EC:2.1.2.1
Gene Prediction Quality  validated Protein length 

Sequence

Length: 567  
Kegg Orthology  K00600

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0 Synonyms

6 GO Terms

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0030170 pyridoxal phosphate binding Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0004372 glycine hydroxymethyltransferase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.
GO:0006544 glycine metabolic process The chemical reactions and pathways involving glycine, aminoethanoic acid.
GO:0006563 L-serine metabolic process The chemical reactions and pathways involving L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.

41 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|cic:CICLE_v10019689mg 1 566 + 566 Gaps:37 100.00 529 87.15 0.0 hypothetical protein
blastp_kegg lcl|cit:102610283 1 566 + 566 Gaps:37 100.00 529 87.15 0.0 serine hydroxymethyltransferase 3 chloroplastic-like
blastp_kegg lcl|pop:POPTR_0006s24840g 1 566 + 566 Gaps:37 100.00 529 86.39 0.0 POPTRDRAFT_819509 glycine hydroxymethyltransferase family protein
blastp_kegg lcl|vvi:100250728 1 566 + 566 Gaps:38 100.00 528 85.98 0.0 serine hydroxymethyltransferase-like
blastp_kegg lcl|pxb:103959893 1 566 + 566 Gaps:38 100.00 530 84.53 0.0 serine hydroxymethyltransferase 3 chloroplastic-like
blastp_kegg lcl|sly:101267301 1 566 + 566 Gaps:41 100.00 527 85.58 0.0 serine hydroxymethyltransferase mitochondrial-like
blastp_kegg lcl|pxb:103959444 1 566 + 566 Gaps:38 100.00 530 84.53 0.0 serine hydroxymethyltransferase 3 chloroplastic-like
blastp_kegg lcl|tcc:TCM_037262 1 566 + 566 Gaps:43 100.00 523 86.81 0.0 Serine hydroxymethyltransferase 3 isoform 1
blastp_kegg lcl|csv:101212892 1 566 + 566 Gaps:38 100.00 528 85.04 0.0 serine hydroxymethyltransferase mitochondrial-like
blastp_kegg lcl|mdm:103444223 1 566 + 566 Gaps:38 100.00 530 84.15 0.0 serine hydroxymethyltransferase 3 chloroplastic-like
blastp_pdb 3ou5_A 83 566 + 484 Gaps:51 92.45 490 60.71 0.0 mol:protein length:490 Serine hydroxymethyltransferase mitochondria
blastp_pdb 1bj4_A 70 566 + 497 Gaps:49 99.57 470 59.83 0.0 mol:protein length:470 PROTEIN (SERINE HYDROXYMETHYLTRANSFERASE)
blastp_pdb 1eji_D 73 566 + 494 Gaps:50 97.49 478 60.09 0.0 mol:protein length:478 SERINE HYDROXYMETHYLTRANSFERASE
blastp_pdb 1eji_C 73 566 + 494 Gaps:50 97.49 478 60.09 0.0 mol:protein length:478 SERINE HYDROXYMETHYLTRANSFERASE
blastp_pdb 1eji_B 73 566 + 494 Gaps:50 97.49 478 60.09 0.0 mol:protein length:478 SERINE HYDROXYMETHYLTRANSFERASE
blastp_pdb 1eji_A 73 566 + 494 Gaps:50 97.49 478 60.09 0.0 mol:protein length:478 SERINE HYDROXYMETHYLTRANSFERASE
blastp_pdb 1cj0_B 74 566 + 493 Gaps:48 98.94 470 60.00 0.0 mol:protein length:470 PROTEIN (SERINE HYDROXYMETHYLTRANSFERASE)
blastp_pdb 1cj0_A 74 566 + 493 Gaps:48 98.94 470 60.00 0.0 mol:protein length:470 PROTEIN (SERINE HYDROXYMETHYLTRANSFERASE)
blastp_pdb 1ls3_D 74 566 + 493 Gaps:48 96.27 483 60.00 0.0 mol:protein length:483 Serine Hydroxymethyltransferase
blastp_pdb 1ls3_C 74 566 + 493 Gaps:48 96.27 483 60.00 0.0 mol:protein length:483 Serine Hydroxymethyltransferase
blastp_uniprot_sprot sp|Q94JQ3|GLYP3_ARATH 1 566 + 566 Gaps:37 100.00 529 79.02 0.0 Serine hydroxymethyltransferase 3 chloroplastic OS Arabidopsis thaliana GN SHM3 PE 1 SV 2
blastp_uniprot_sprot sp|Q94C74|GLYM2_ARATH 62 566 + 505 Gaps:49 92.46 517 60.67 0.0 Serine hydroxymethyltransferase 2 mitochondrial OS Arabidopsis thaliana GN SHM2 PE 1 SV 2
blastp_uniprot_sprot sp|P50433|GLYM_SOLTU 44 566 + 523 Gaps:47 95.37 518 59.11 0.0 Serine hydroxymethyltransferase mitochondrial OS Solanum tuberosum PE 2 SV 1
blastp_uniprot_sprot sp|Q9SZJ5|GLYM1_ARATH 79 566 + 488 Gaps:48 88.59 517 61.79 0.0 Serine hydroxymethyltransferase 1 mitochondrial OS Arabidopsis thaliana GN SHM1 PE 1 SV 1
blastp_uniprot_sprot sp|P34899|GLYM_PEA 87 566 + 480 Gaps:46 86.87 518 62.44 0.0 Serine hydroxymethyltransferase mitochondrial OS Pisum sativum PE 1 SV 1
blastp_uniprot_sprot sp|P49358|GLYM2_FLAPR 61 566 + 506 Gaps:49 91.88 517 60.42 0.0 Serine hydroxymethyltransferase 2 mitochondrial OS Flaveria pringlei PE 2 SV 1
blastp_uniprot_sprot sp|P34898|GLYC_NEUCR 77 564 + 488 Gaps:51 95.62 480 60.35 0.0 Serine hydroxymethyltransferase cytosolic OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) GN for PE 3 SV 2
blastp_uniprot_sprot sp|P49357|GLYM1_FLAPR 61 566 + 506 Gaps:47 91.88 517 59.58 0.0 Serine hydroxymethyltransferase 1 mitochondrial OS Flaveria pringlei PE 2 SV 1
blastp_uniprot_sprot sp|Q5E9P9|GLYC_BOVIN 83 566 + 484 Gaps:50 94.21 484 60.53 0.0 Serine hydroxymethyltransferase cytosolic OS Bos taurus GN SHMT1 PE 2 SV 3
blastp_uniprot_sprot sp|P35623|GLYC_SHEEP 83 566 + 484 Gaps:50 94.21 484 60.75 0.0 Serine hydroxymethyltransferase cytosolic OS Ovis aries GN SHMT1 PE 1 SV 3

16 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
SUPERFAMILY 81 452 372 SSF53383 none none IPR015424
PANTHER 477 566 90 PTHR11680 "KEGG:00260+2.1.2.1","KEGG:00460+2.1.2.1","KEGG:00630+2.1.2.1","KEGG:00670+2.1.2.1","KEGG:00680+2.1.2.1","MetaCyc:PWY-1622","MetaCyc:PWY-181","MetaCyc:PWY-2161","MetaCyc:PWY-2201","MetaCyc:PWY-3661","MetaCyc:PWY-3661-1","MetaCyc:PWY-3841","MetaCyc:PWY-5497","UniPathway:UPA00193","UniPathway:UPA00288";signature_desc=SERINE HYDROXYMETHYLTRANSFERASE none IPR001085
Hamap 82 565 484 MF_00051 "KEGG:00260+2.1.2.1","KEGG:00460+2.1.2.1","KEGG:00630+2.1.2.1","KEGG:00670+2.1.2.1","KEGG:00680+2.1.2.1","MetaCyc:PWY-1622","MetaCyc:PWY-181","MetaCyc:PWY-2161","MetaCyc:PWY-2201","MetaCyc:PWY-3661","MetaCyc:PWY-3661-1","MetaCyc:PWY-3841","MetaCyc:PWY-5497","UniPathway:UPA00193","UniPathway:UPA00288" Serine hydroxymethyltransferase [glyA]. IPR001085
Gene3D 373 441 69 G3DSA:3.90.1150.10 none none IPR015422
Gene3D 475 565 91 G3DSA:3.90.1150.10 none none IPR015422
Phobius 1 441 441 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Gene3D 112 372 261 G3DSA:3.40.640.10 none none IPR015421
ProSitePatterns 306 322 17 PS00096 "KEGG:00260+2.1.2.1","KEGG:00460+2.1.2.1","KEGG:00630+2.1.2.1","KEGG:00670+2.1.2.1","KEGG:00680+2.1.2.1","MetaCyc:PWY-1622","MetaCyc:PWY-181","MetaCyc:PWY-2161","MetaCyc:PWY-2201","MetaCyc:PWY-3661","MetaCyc:PWY-3661-1","MetaCyc:PWY-3841","MetaCyc:PWY-5497","UniPathway:UPA00193","UniPathway:UPA00288" Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. IPR019798
PANTHER 46 439 394 PTHR11680 "KEGG:00260+2.1.2.1","KEGG:00460+2.1.2.1","KEGG:00630+2.1.2.1","KEGG:00670+2.1.2.1","KEGG:00680+2.1.2.1","MetaCyc:PWY-1622","MetaCyc:PWY-181","MetaCyc:PWY-2161","MetaCyc:PWY-2201","MetaCyc:PWY-3661","MetaCyc:PWY-3661-1","MetaCyc:PWY-3841","MetaCyc:PWY-5497","UniPathway:UPA00193","UniPathway:UPA00288";signature_desc=SERINE HYDROXYMETHYLTRANSFERASE none IPR001085
PANTHER 46 439 394 PTHR11680:SF4 none none none
PANTHER 477 566 90 PTHR11680:SF4 none none none
Phobius 442 462 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
SUPERFAMILY 471 565 95 SSF53383 none none IPR015424
Pfam 475 510 36 PF00464 "KEGG:00260+2.1.2.1","KEGG:00460+2.1.2.1","KEGG:00630+2.1.2.1","KEGG:00670+2.1.2.1","KEGG:00680+2.1.2.1","MetaCyc:PWY-1622","MetaCyc:PWY-181","MetaCyc:PWY-2161","MetaCyc:PWY-2201","MetaCyc:PWY-3661","MetaCyc:PWY-3661-1","MetaCyc:PWY-3841","MetaCyc:PWY-5497","UniPathway:UPA00193","UniPathway:UPA00288" Serine hydroxymethyltransferase IPR001085
Pfam 83 440 358 PF00464 "KEGG:00260+2.1.2.1","KEGG:00460+2.1.2.1","KEGG:00630+2.1.2.1","KEGG:00670+2.1.2.1","KEGG:00680+2.1.2.1","MetaCyc:PWY-1622","MetaCyc:PWY-181","MetaCyc:PWY-2161","MetaCyc:PWY-2201","MetaCyc:PWY-3661","MetaCyc:PWY-3661-1","MetaCyc:PWY-3841","MetaCyc:PWY-5497","UniPathway:UPA00193","UniPathway:UPA00288" Serine hydroxymethyltransferase IPR001085
Phobius 463 566 104 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none

0 Localization

5 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran1_2003_QTL2_peak_Bud_burst_A4 Qrob_Chr02 2 s_1B0H8U_259 s_1CB1VL_554 17 0 87 lod 3,3 8,7
Bourran2_2003_QTL8_peak_Bud_burst_3P Qrob_Chr02 2 s_1ANG6_1446 v_11270_161 40 0 72 lod 4,4 9,9
Bourran2_2014_nP_A4 Qrob_Chr11 11 s_1B58GB_1413 s_1A5BYY_1671 11,15 0 42,38 lod 1,8913 4,5
Bourran2_2015_nPriLBD_A4 Qrob_Chr02 2 s_1CP5DI_1183 s_1A63ZX_1277 24,87 24,63 26,18 lod 3.8 7
Bourran1_2004_QTL3_peak_Bud_burst_A4 Qrob_Chr02 2 s_1B0H8U_259 s_1CB1VL_554 17 0 46 lod 2,9 6,4

0 Targeting