Protein : Qrob_P0215950.2 Q. robur

Protein Identifier  ? Qrob_P0215950.2 Organism . Name  Quercus robur
Score  0.0 Score Type  egn
Protein Description  (M=20) K00025 - malate dehydrogenase [EC:1.1.1.37] Code Enzyme  EC:1.1.1.37
Gene Prediction Quality  validated Protein length 

Sequence

Length: 299  
Kegg Orthology  K00025

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0 Synonyms

8 GO Terms

Identifier Name Description
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0005975 carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
GO:0006108 malate metabolic process The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
GO:0016615 malate dehydrogenase activity Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate.
GO:0019752 carboxylic acid metabolic process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).

43 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|cic:CICLE_v10021075mg 1 298 + 298 Gaps:11 93.07 332 73.46 1e-152 hypothetical protein
blastp_kegg lcl|csv:101221189 1 298 + 298 Gaps:11 84.89 364 73.79 9e-152 malate dehydrogenase cytoplasmic-like
blastp_kegg lcl|cmo:103483128 1 298 + 298 Gaps:11 84.89 364 72.82 3e-151 malate dehydrogenase cytoplasmic-like
blastp_kegg lcl|cit:102615934 1 298 + 298 Gaps:11 84.43 366 73.46 4e-151 malate dehydrogenase cytoplasmic-like
blastp_kegg lcl|vvi:100256452 1 298 + 298 Gaps:11 93.07 332 72.49 3e-149 malate dehydrogenase cytoplasmic-like
blastp_kegg lcl|rcu:RCOM_1609380 1 298 + 298 Gaps:11 93.07 332 72.82 6e-149 malate dehydrogenase putative (EC:1.1.1.37)
blastp_kegg lcl|pop:POPTR_0002s14270g 1 298 + 298 Gaps:11 93.07 332 72.17 2e-148 POPTRDRAFT_551994 hypothetical protein
blastp_kegg lcl|pxb:103953311 1 298 + 298 Gaps:11 82.18 376 71.84 9e-148 malate dehydrogenase-like
blastp_kegg lcl|sot:102585937 1 298 + 298 Gaps:11 93.07 332 70.55 1e-147 malate dehydrogenase cytoplasmic-like
blastp_kegg lcl|mdm:103435358 1 298 + 298 Gaps:11 82.18 376 71.52 6e-147 malate dehydrogenase-like
blastp_pdb 5mdh_B 2 298 + 297 Gaps:12 92.79 333 51.13 2e-92 mol:protein length:333 MALATE DEHYDROGENASE
blastp_pdb 5mdh_A 2 298 + 297 Gaps:12 92.79 333 51.13 2e-92 mol:protein length:333 MALATE DEHYDROGENASE
blastp_pdb 4mdh_B 2 298 + 297 Gaps:12 92.51 334 51.13 2e-92 mol:protein length:334 CYTOPLASMIC MALATE DEHYDROGENASE
blastp_pdb 4mdh_A 2 298 + 297 Gaps:12 92.51 334 51.13 2e-92 mol:protein length:334 CYTOPLASMIC MALATE DEHYDROGENASE
blastp_pdb 2cvq_B 2 291 + 290 Gaps:12 90.52 327 47.64 5e-80 mol:protein length:327 Malate dehydrogenase
blastp_pdb 2cvq_A 2 291 + 290 Gaps:12 90.52 327 47.64 5e-80 mol:protein length:327 Malate dehydrogenase
blastp_pdb 1y7t_B 2 291 + 290 Gaps:12 90.52 327 47.64 5e-80 mol:protein length:327 Malate dehydrogenase
blastp_pdb 1y7t_A 2 291 + 290 Gaps:12 90.52 327 47.64 5e-80 mol:protein length:327 Malate dehydrogenase
blastp_pdb 1iz9_B 2 291 + 290 Gaps:12 90.52 327 47.64 5e-80 mol:protein length:327 MALATE DEHYDROGENASE
blastp_pdb 1iz9_A 2 291 + 290 Gaps:12 90.52 327 47.64 5e-80 mol:protein length:327 MALATE DEHYDROGENASE
blastp_uniprot_sprot sp|Q08062|MDHC_MAIZE 1 297 + 297 Gaps:11 92.77 332 69.81 6e-146 Malate dehydrogenase cytoplasmic OS Zea mays PE 1 SV 2
blastp_uniprot_sprot sp|Q7XDC8|MDHC_ORYSJ 1 298 + 298 Gaps:11 93.07 332 68.93 3e-145 Malate dehydrogenase cytoplasmic OS Oryza sativa subsp. japonica GN Os10g0478200 PE 1 SV 3
blastp_uniprot_sprot sp|O48905|MDHC_MEDSA 1 298 + 298 Gaps:11 93.07 332 69.58 6e-144 Malate dehydrogenase cytoplasmic OS Medicago sativa GN CMDH PE 1 SV 1
blastp_uniprot_sprot sp|Q9FSF0|MDH_TOBAC 1 297 + 297 Gaps:11 92.77 332 69.16 1e-142 Malate dehydrogenase OS Nicotiana tabacum GN MD1 PE 1 SV 1
blastp_uniprot_sprot sp|O24047|MDHC_MESCR 1 297 + 297 Gaps:11 92.77 332 69.48 2e-141 Malate dehydrogenase cytoplasmic OS Mesembryanthemum crystallinum GN MDH PE 2 SV 1
blastp_uniprot_sprot sp|P57106|MDHC2_ARATH 1 298 + 298 Gaps:11 93.07 332 68.28 3e-141 Malate dehydrogenase cytoplasmic 2 OS Arabidopsis thaliana GN At5g43330 PE 2 SV 1
blastp_uniprot_sprot sp|P93819|MDHC1_ARATH 1 298 + 298 Gaps:11 93.07 332 68.61 8e-141 Malate dehydrogenase cytoplasmic 1 OS Arabidopsis thaliana GN At1g04410 PE 1 SV 2
blastp_uniprot_sprot sp|Q9SML8|MDHC_BETVU 1 297 + 297 Gaps:11 92.77 332 67.86 9e-140 Malate dehydrogenase cytoplasmic OS Beta vulgaris GN NR1 PE 1 SV 1
blastp_uniprot_sprot sp|P40925|MDHC_HUMAN 2 298 + 297 Gaps:12 92.51 334 51.46 3e-93 Malate dehydrogenase cytoplasmic OS Homo sapiens GN MDH1 PE 1 SV 4
blastp_uniprot_sprot sp|P14152|MDHC_MOUSE 2 298 + 297 Gaps:12 92.51 334 51.13 1e-92 Malate dehydrogenase cytoplasmic OS Mus musculus GN Mdh1 PE 1 SV 3

10 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 1 298 298 PTHR23382 "KEGG:00020+1.1.1.37","KEGG:00270+1.1.1.37","KEGG:00620+1.1.1.37","KEGG:00630+1.1.1.37","KEGG:00680+1.1.1.37","KEGG:00710+1.1.1.37","KEGG:00720+1.1.1.37","MetaCyc:PWY-1622","MetaCyc:PWY-5392","MetaCyc:PWY-561","MetaCyc:PWY-5690","MetaCyc:PWY-5913","MetaCyc:PWY-6728","MetaCyc:PWY-6969","MetaCyc:PWY-7115","MetaCyc:PWY-7383";signature_desc=MALATE DEHYDROGENASE none IPR010945
SUPERFAMILY 134 297 164 SSF56327 none none IPR015955
TIGRFAM 1 293 293 TIGR01759 "KEGG:00020+1.1.1.37","KEGG:00270+1.1.1.37","KEGG:00620+1.1.1.37","KEGG:00630+1.1.1.37","KEGG:00680+1.1.1.37","KEGG:00710+1.1.1.37","KEGG:00720+1.1.1.37","MetaCyc:PWY-1622","MetaCyc:PWY-5392","MetaCyc:PWY-561","MetaCyc:PWY-5690","MetaCyc:PWY-5913","MetaCyc:PWY-6728","MetaCyc:PWY-6969","MetaCyc:PWY-7115","MetaCyc:PWY-7383" MalateDH-SF1: malate dehydrogenase IPR010945
SUPERFAMILY 6 132 127 SSF51735 none none none
Pfam 16 130 115 PF00056 none lactate/malate dehydrogenase, NAD binding domain IPR001236
PIRSF 1 295 295 PIRSF000102 none none IPR001557
ProSitePatterns 133 145 13 PS00068 "KEGG:00020+1.1.1.37","KEGG:00270+1.1.1.37","KEGG:00620+1.1.1.37","KEGG:00630+1.1.1.37","KEGG:00680+1.1.1.37","KEGG:00710+1.1.1.37","KEGG:00720+1.1.1.37","MetaCyc:PWY-1622","MetaCyc:PWY-5392","MetaCyc:PWY-561","MetaCyc:PWY-5690","MetaCyc:PWY-5913","MetaCyc:PWY-6728","MetaCyc:PWY-6969","MetaCyc:PWY-7115","MetaCyc:PWY-7383","Reactome:REACT_474" Malate dehydrogenase active site signature. IPR001252
Gene3D 133 297 165 G3DSA:3.90.110.10 none none IPR015955
Pfam 134 293 160 PF02866 none lactate/malate dehydrogenase, alpha/beta C-terminal domain IPR022383
Gene3D 2 132 131 G3DSA:3.40.50.720 none none IPR016040

0 Localization

3 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2015_nEpis_3P Qrob_Chr12 12 s_1AOES6_1466 s_1B0DDG_1094 28,97 28,55 30,1 lod 3.6 8.4
Bourran2_2015_nP_3P Qrob_Chr12 12 v_10140_295 v_838_303 16 14,69 18,01 lod 5.1 13.7
Bourran2_2015_nSecLBD_3P Qrob_Chr12 12 s_A4YYC_633 s_2F1IZB_703 18,64 18,01 21,53 lod 6.5 17.2

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 24   Secretory pathway 1 0.928 0.026 NON-PLANT 24