Protein : Qrob_P0207460.2 Q. robur
Protein Identifier  ? Qrob_P0207460.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=2) PF00488//PF01541 - MutS domain V // GIY-YIG catalytic domain Gene Prediction Quality  validated
Protein length 

Sequence

Length: 280  
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0005524 ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0006298 mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.
GO:0030983 mismatched DNA binding Interacting selectively and non-covalently with double-stranded DNA containing one or more mismatches.

17 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pxb:103933658 1 278 + 278 Gaps:37 27.46 1140 66.45 3e-128 DNA mismatch repair protein MSH1 mitochondrial
blastp_kegg lcl|pper:PRUPE_ppa000475mg 1 269 + 269 Gaps:38 26.66 1144 66.89 2e-125 hypothetical protein
blastp_kegg lcl|pop:POPTR_0010s07550g 1 277 + 277 Gaps:30 26.81 1130 63.70 2e-118 POPTRDRAFT_885217 chloroplast mutator family protein
blastp_kegg lcl|fve:101291235 1 278 + 278 Gaps:40 24.55 1279 63.69 5e-118 DNA mismatch repair protein MSH1 mitochondrial-like
blastp_kegg lcl|vvi:100266612 1 268 + 268 Gaps:38 26.75 1144 63.07 7e-116 uncharacterized LOC100266612
blastp_kegg lcl|csv:101228304 1 279 + 279 Gaps:37 42.96 675 63.10 8e-115 DNA mismatch repair protein MSH1 mitochondrial-like
blastp_kegg lcl|mtr:MTR_1g045670 1 269 + 269 Gaps:47 24.88 1230 60.78 2e-111 DNA mismatch repair protein mutS
blastp_kegg lcl|cmo:103483539 1 279 + 279 Gaps:42 27.89 1151 58.26 3e-111 DNA mismatch repair protein MSH1 mitochondrial
blastp_kegg lcl|cam:101504596 1 269 + 269 Gaps:38 26.91 1141 58.31 4e-111 DNA mismatch repair protein MSH1 mitochondrial-like
blastp_kegg lcl|cit:102611883 1 269 + 269 Gaps:42 26.82 1137 60.33 2e-110 DNA mismatch repair protein MSH1 mitochondrial-like
blastp_uniprot_sprot sp|Q84LK0|MSH1_ARATH 1 279 + 279 Gaps:52 25.85 1118 56.06 3e-97 DNA mismatch repair protein MSH1 mitochondrial OS Arabidopsis thaliana GN MSH1 PE 1 SV 1
rpsblast_cdd gnl|CDD|198385 188 257 + 70 Gaps:2 100.00 72 50.00 8e-20 cd10438 GIY-YIG_MSH Catalytic GIY-YIG domain of eukaryotic DNA mismatch repair protein MutS homologs. This family represents a putative GIY-YIG nuclease domain C-terminally fused to the DNA-repair ATPase on a small group of eukaryotic DNA mismatch repair protein mutS homologs (MSH). The MSH proteins in this family do not have the zinc finger domain but have a predicted mitochondrial localization. They might play roles in the recognition and repair of errors made during the replication of DNA. The prototype of this family is the protein encoded by the chloroplast mutator (CHM) locus from Arabidopsis thaliana. It is suggested that this protein could be involved in the maintenance of mitochondrial genome stability.
rpsblast_cdd gnl|CDD|73002 1 86 + 86 Gaps:21 52.97 202 28.04 4e-11 cd03243 ABC_MutS_homologs The MutS protein initiates DNA mismatch repair by recognizing mispaired and unpaired bases embedded in duplex DNA and activating endo- and exonucleases to remove the mismatch. Members of the MutS family also possess a conserved ATPase activity that belongs to the ATP binding cassette (ABC) superfamily. MutS homologs (MSH) have been identified in most prokaryotic and all eukaryotic organisms examined. Prokaryotes have two homologs (MutS1 and MutS2) whereas seven MSH proteins (MSH1 to MSH7) have been identified in eukaryotes. The homodimer MutS1 and heterodimers MSH2-MSH3 and MSH2-MSH6 are primarily involved in mitotic mismatch repair whereas MSH4-MSH5 is involved in resolution of Holliday junctions during meiosis. All members of the MutS family contain the highly conserved Walker A/B ATPase domain and many share a common mechanism of action. MutS1 MSH2-MSH3 MSH2-MSH6 and MSH4-MSH5 dimerize to form sliding clamps and recognition of specific DNA structures or lesions results in ADP/ATP exchange..
rpsblast_cdd gnl|CDD|197777 1 98 + 98 Gaps:22 64.86 185 24.17 3e-10 smart00534 MUTSac ATPase domain of DNA mismatch repair MUTS family.
rpsblast_cdd gnl|CDD|73045 20 94 + 75 Gaps:8 37.16 218 27.16 5e-07 cd03286 ABC_MSH6_euk MutS6 homolog in eukaryotes. The MutS protein initiates DNA mismatch repair by recognizing mispaired and unpaired bases embedded in duplex DNA and activating endo- and exonucleases to remove the mismatch. Members of the MutS family possess C-terminal domain with a conserved ATPase activity that belongs to the ATP binding cassette (ABC) superfamily. MutS homologs (MSH) have been identified in most prokaryotic and all eukaryotic organisms examined. Prokaryotes have two homologs (MutS1 and MutS2) whereas seven MSH proteins (MSH1 to MSH7) have been identified in eukaryotes. The homodimer MutS1 and heterodimers MSH2-MSH3 and MSH2-MSH6 are primarily involved in mitotic mismatch repair whereas MSH4-MSH5 is involved in resolution of Holliday junctions during meiosis. All members of the MutS family contain the highly conserved Walker A/B ATPase domain and many share a common mechanism of action. MutS1 MSH2-MSH3 MSH2-MSH6 and MSH4-MSH5 dimerize to form sliding clamps and recognition of specific DNA structures or lesions results in ADP/ATP exchange..
rpsblast_cdd gnl|CDD|30598 1 122 + 122 Gaps:22 17.08 843 21.53 6e-07 COG0249 MutS Mismatch repair ATPase (MutS family) [DNA replication recombination and repair].
rpsblast_kog gnl|CDD|35438 27 276 + 250 Gaps:34 22.58 1125 18.11 5e-28 KOG0217 KOG0217 KOG0217 Mismatch repair ATPase MSH6 (MutS family) [Replication recombination and repair].

7 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Pfam 21 97 77 PF00488 none MutS domain V IPR000432
Pfam 189 249 61 PF01541 none GIY-YIG catalytic domain IPR000305
Gene3D 19 98 80 G3DSA:3.40.50.300 none none IPR027417
SUPERFAMILY 188 250 63 SSF82771 none none IPR000305
SMART 1 99 99 SM00534 none ATPase domain of DNA mismatch repair MUTS family IPR000432
PANTHER 1 187 187 PTHR11361 none none none
PANTHER 1 187 187 PTHR11361:SF82 none none none

0 Localization

11 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran2_2014_aSeqBC_A4 Qrob_Chr08 8 v_15999_278 v_AP13YL15_395 32,52 4,22 57,22 lod 2,7561 6,7
Bourran2_2014_nFork*_A4 Qrob_Chr08 8 PIE175 s_1CD7GJ_1398 31,22 5,24 57,24 lod 2,6724 6,8
Bourran2_2014_nLBD*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,25 0 35,55 lod 2,5951 6
Bourran2_2014_nP*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,19 0 31,97 lod 2,8472 6
Bourran2_2014_nPriLBD_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,36 0 30,43 lod 2,5806 5,1
Bourran2_2015_rEpiBC_3P Qrob_Chr08 8 s_A9TNV_543 v_11837_70 9,93 9,83 11,15 lod 3.3 7.3
Champenoux_2015_nSeqBC_A4 Qrob_Chr08 8 v_AD7YD13_501 s_1A7IED_780 43,44 43,42 43,99 lod 3.7 8.9
Bourran2_2014_nEpis*_3P Qrob_Chr08 8 s_1DA4QW_688 s_1DNI7D_820 17,96 0 37,75 lod 2,9745 7,5
Bourran2_2014_nPriBD_3P Qrob_Chr11 11 v_11486_194 s_1AT3E_2335 5,54 0,4 20,6 lod 2,6345 5,9

0 Targeting