| Analysis | rpsblast_cdd | Start | 20 |
| End | 94 | Strand | + |
| Length | 75 | Note | Gaps:8 |
| Hit Coverage | 37.16 | Hit Length | 218 |
| Hit Pident | 27.16 | E Val | 5e-07 |
| Hit Description | cd03286 ABC_MSH6_euk MutS6 homolog in eukaryotes. The MutS protein initiates DNA mismatch repair by recognizing mispaired and unpaired bases embedded in duplex DNA and activating endo- and exonucleases to remove the mismatch. Members of the MutS family possess C-terminal domain with a conserved ATPase activity that belongs to the ATP binding cassette (ABC) superfamily. MutS homologs (MSH) have been identified in most prokaryotic and all eukaryotic organisms examined. Prokaryotes have two homologs (MutS1 and MutS2) whereas seven MSH proteins (MSH1 to MSH7) have been identified in eukaryotes. The homodimer MutS1 and heterodimers MSH2-MSH3 and MSH2-MSH6 are primarily involved in mitotic mismatch repair whereas MSH4-MSH5 is involved in resolution of Holliday junctions during meiosis. All members of the MutS family contain the highly conserved Walker A/B ATPase domain and many share a common mechanism of action. MutS1 MSH2-MSH3 MSH2-MSH6 and MSH4-MSH5 dimerize to form sliding clamps and recognition of specific DNA structures or lesions results in ADP/ATP exchange.. | Hit Pcons | 16.05 |
| Name | Qrob_P0207460.2 |
| Protein Identifier |
Organism . Name |
Score | Score Type | Protein Description | Alias (in v1) | Code Enzyme | Gene Prediction Quality |
|---|---|---|---|---|---|---|---|
| Qrob_P0207460.2 | Quercus robur | 100.0 | egn | (M=2) PF00488//PF01541 - MutS domain V // GIY-YIG catalytic domain | validated |
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