Protein : Qrob_P0139340.2 Q. robur
Protein Identifier  ? Qrob_P0139340.2 Organism . Name  Quercus robur
Score  88.1 Score Type  egn
Protein Description  (M=5) K03164 - DNA topoisomerase II [EC:5.99.1.3] Code Enzyme  EC:5.99.1.3
Gene Prediction Quality  validated Protein length 

Sequence

Length: 851  
Kegg Orthology  K03164
Paste the following link
Lists
This Protein isn't in any lists. Upload a list.

Sequence Feature Displayer

Protein Sequence Displayer

J Browse Displayer

0 Synonyms

5 GO Terms

Identifier Name Description
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0005524 ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
GO:0006265 DNA topological change The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
GO:0006259 DNA metabolic process Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.

41 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|vvi:100253371 3 828 + 826 Gaps:66 57.49 1489 68.57 0.0 DNA topoisomerase 2-like
blastp_kegg lcl|pmum:103330635 3 816 + 814 Gaps:60 57.38 1471 68.48 0.0 DNA topoisomerase 2
blastp_kegg lcl|pper:PRUPE_ppa000202mg 3 816 + 814 Gaps:61 57.31 1471 68.45 0.0 hypothetical protein
blastp_kegg lcl|tcc:TCM_042757 3 813 + 811 Gaps:75 56.21 1473 68.24 0.0 DNA topoisomerase 2 isoform 1
blastp_kegg lcl|cmo:103500322 3 821 + 819 Gaps:75 57.32 1490 67.45 0.0 DNA topoisomerase 2
blastp_kegg lcl|fve:101308524 3 817 + 815 Gaps:69 57.32 1469 68.88 0.0 DNA topoisomerase 2-like
blastp_kegg lcl|mdm:103438420 3 810 + 808 Gaps:75 56.70 1462 68.64 0.0 DNA topoisomerase 2-like
blastp_kegg lcl|mdm:103409964 3 810 + 808 Gaps:75 57.77 1435 68.52 0.0 DNA topoisomerase 2-like
blastp_kegg lcl|pxb:103945915 3 817 + 815 Gaps:69 56.99 1467 67.94 0.0 DNA topoisomerase 2-like
blastp_kegg lcl|pxb:103945911 3 817 + 815 Gaps:69 56.99 1467 67.94 0.0 DNA topoisomerase 2-like
blastp_pdb 3qx3_B 4 682 + 679 Gaps:70 89.29 803 46.72 0.0 mol:protein length:803 DNA topoisomerase 2-beta
blastp_pdb 3qx3_A 4 682 + 679 Gaps:70 89.29 803 46.72 0.0 mol:protein length:803 DNA topoisomerase 2-beta
blastp_pdb 3l4k_A 4 680 + 677 Gaps:76 95.24 757 43.97 0.0 mol:protein length:757 DNA topoisomerase 2
blastp_pdb 3l4j_A 4 680 + 677 Gaps:76 95.24 757 43.97 0.0 mol:protein length:757 DNA topoisomerase 2
blastp_pdb 2rgr_A 4 680 + 677 Gaps:76 94.99 759 43.83 0.0 mol:protein length:759 DNA topoisomerase 2
blastp_pdb 1bjt_A 4 680 + 677 Gaps:76 90.92 793 43.83 0.0 mol:protein length:793 TOPOISOMERASE II
blastp_pdb 1bgw_A 4 680 + 677 Gaps:76 90.92 793 43.83 0.0 mol:protein length:793 TOPOISOMERASE
blastp_pdb 2xcq_A 7 395 + 389 Gaps:44 54.96 726 28.32 1e-27 mol:protein length:726 DNA GYRASE SUBUNIT B DNA GYRASE SUBUNIT A
blastp_pdb 2xco_A 7 395 + 389 Gaps:44 54.96 726 28.32 1e-27 mol:protein length:726 DNA GYRASE SUBUNIT B DNA GYRASE SUBUNIT A
blastp_pdb 2xcr_U 7 395 + 389 Gaps:44 54.96 726 28.07 3e-27 mol:protein length:726 DNA GYRASE SUBUNIT B DNA GYRASE SUBUNIT A
blastp_uniprot_sprot sp|P30182|TOP2_ARATH 4 800 + 797 Gaps:93 58.25 1473 56.29 0.0 DNA topoisomerase 2 OS Arabidopsis thaliana GN TOP2 PE 2 SV 2
blastp_uniprot_sprot sp|O24308|TOP2_PEA 3 827 + 825 Gaps:86 56.57 1462 56.47 0.0 DNA topoisomerase 2 OS Pisum sativum GN TOP2 PE 2 SV 1
blastp_uniprot_sprot sp|P08096|TOP2_SCHPO 4 693 + 690 Gaps:82 48.89 1485 46.01 0.0 DNA topoisomerase 2 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN top2 PE 1 SV 2
blastp_uniprot_sprot sp|Q02880|TOP2B_HUMAN 4 691 + 688 Gaps:69 44.71 1626 46.22 0.0 DNA topoisomerase 2-beta OS Homo sapiens GN TOP2B PE 1 SV 3
blastp_uniprot_sprot sp|Q64399|TOP2B_CRILO 4 691 + 688 Gaps:71 45.10 1612 46.63 0.0 DNA topoisomerase 2-beta OS Cricetulus longicaudatus GN TOP2B PE 2 SV 1
blastp_uniprot_sprot sp|Q64511|TOP2B_MOUSE 4 691 + 688 Gaps:71 45.10 1612 46.63 0.0 DNA topoisomerase 2-beta OS Mus musculus GN Top2b PE 1 SV 2
blastp_uniprot_sprot sp|O42131|TOP2B_CHICK 4 819 + 816 Gaps:108 51.01 1627 44.22 0.0 DNA topoisomerase 2-beta OS Gallus gallus GN TOP2B PE 2 SV 1
blastp_uniprot_sprot sp|P87078|TOP2_CANAX 4 706 + 703 Gaps:96 52.09 1461 42.58 0.0 DNA topoisomerase 2 OS Candida albicans GN TOP2 PE 3 SV 1
blastp_uniprot_sprot sp|O42130|TOP2A_CHICK 4 681 + 678 Gaps:75 45.91 1553 45.30 0.0 DNA topoisomerase 2-alpha OS Gallus gallus GN TOP2A PE 2 SV 2
blastp_uniprot_sprot sp|P41516|TOP2A_RAT 4 683 + 680 Gaps:75 47.38 1526 46.33 0.0 DNA topoisomerase 2-alpha OS Rattus norvegicus GN Top2a PE 2 SV 1

37 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
SMART 227 661 435 SM00434 none DNA Topoisomerase IV IPR002205
Phobius 15 830 816 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 3 10 8 SIGNAL_PEPTIDE_H_REGION none Hydrophobic region of a signal peptide. none
Coils 656 687 32 Coil none none none
Gene3D 536 652 117 G3DSA:1.10.268.10 none none IPR013757
Phobius 831 849 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 850 850 1 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Gene3D 415 535 121 G3DSA:3.30.1360.40 none none IPR024946
PRINTS 152 164 13 PR01158 none Topoisomerase II signature IPR001154
PRINTS 39 52 14 PR01158 none Topoisomerase II signature IPR001154
PRINTS 82 97 16 PR01158 none Topoisomerase II signature IPR001154
PRINTS 500 526 27 PR01158 none Topoisomerase II signature IPR001154
PRINTS 307 329 23 PR01158 none Topoisomerase II signature IPR001154
PRINTS 260 283 24 PR01158 none Topoisomerase II signature IPR001154
PRINTS 103 114 12 PR01158 none Topoisomerase II signature IPR001154
PRINTS 337 357 21 PR01158 none Topoisomerase II signature IPR001154
Phobius 1 2 2 SIGNAL_PEPTIDE_N_REGION none N-terminal region of a signal peptide. none
PRINTS 81 98 18 PR00418 none DNA topoisomerase II family signature IPR001241
PRINTS 63 79 17 PR00418 none DNA topoisomerase II family signature IPR001241
PRINTS 102 114 13 PR00418 none DNA topoisomerase II family signature IPR001241
PRINTS 146 162 17 PR00418 none DNA topoisomerase II family signature IPR001241
Coils 633 654 22 Coil none none none
Phobius 1 14 14 SIGNAL_PEPTIDE none Signal peptide region none
SUPERFAMILY 3 677 675 SSF56719 none none IPR013760
PANTHER 4 721 718 PTHR10169 none none none
PANTHER 743 802 60 PTHR10169 none none none
Phobius 11 14 4 SIGNAL_PEPTIDE_C_REGION none C-terminal region of a signal peptide. none
Gene3D 130 164 35 G3DSA:3.30.1490.30 none none none
Gene3D 250 414 165 G3DSA:3.90.199.10 none none IPR013758
SMART 1 204 204 SM00433 none TopoisomeraseII IPR001241

1 Localization

Analysis Start End Length
TMHMM 831 849 18

19 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran1_2003_QTL2_peak_Bud_burst_A4 Qrob_Chr02 2 s_1B0H8U_259 s_1CB1VL_554 17 0 87 lod 3,3 8,7
Bourran2_2004_QTL9_peak_Bud_burst_3P Qrob_Chr02 2 s_1C34E9_788 v_12238_322 50 25 75 lod 4,4 10,1
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL2_d13Cf Qrob_Chr02 2 s_1AQA4Z_1644 s_1AK5QX_947 53.67 14,01 79,68 lod 5.6594 0.03
Bourran1_2004_QTL2_peak_Bud_burst_3P Qrob_Chr02 2 s_1AW12F_382 s_1A77MR_223 42 6 64 lod 3,6 9,6
Bourran2_2002_QTL9_peak_Bud_burst_A4 Qrob_Chr02 2 s_1BFNDA_375 s_1A3VA1_2139 32,5 17 62 lod 3,1 4,2
Bourran2_2003_QTL8_peak_Bud_burst_3P Qrob_Chr02 2 s_1ANG6_1446 v_11270_161 40 0 72 lod 4,4 9,9
Bourran2_2014_nP_A4 Qrob_Chr11 11 s_1B58GB_1413 s_1A5BYY_1671 11,15 0 42,38 lod 1,8913 4,5
Bourran2_2015_nP_A4 Qrob_Chr02 2 s_1A0FUE_1868 s_1A1UAI_500 20,64 20,47 21,36 lod 5.8 10.9
Bourran2_2015_nPriLBD_A4 Qrob_Chr02 2 s_1CP5DI_1183 s_1A63ZX_1277 24,87 24,63 26,18 lod 3.8 7
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL6_d13Cf Qrob_Chr02 2 s_1AEP21_172 v_6048_204 46.33 22,5 65,23 lod 4.972 0.03
Bourran2_2015_nEpis_A4 Qrob_Chr09 9 v_15847_485 v_8329_369 34,94 34,88 37,45 lod 3.1 7
Bourran2_2015_nSecLBD_A4 Qrob_Chr09 9 v_15847_485 v_8329_369 35,81 34,88 37,45 lod 4.4 10.4
Bourran1_2003_QTL1_peak_Bud_burst_3P Qrob_Chr02 2 s_1AR8KI_1183 s_1B0QB1_473 22 6 41 lod 4,2 11,5
Bourran1_2004_QTL3_peak_Bud_burst_A4 Qrob_Chr02 2 s_1B0H8U_259 s_1CB1VL_554 17 0 46 lod 2,9 6,4
Bourran2_2015_nEpiBC_A4 Qrob_Chr07 7 s_1DP9TW_798 v_8128_173 22,61 22,14 22,73 lod 3.1 8.5
Champenoux_2015_nEpis_A4 Qrob_Chr02 2 s_1BAGIZ_823 s_1BN4CB_644 23,06 23,06 23,06 lod 4.9 11
Champenoux_2015_nP_A4 Qrob_Chr02 2 s_1BN4CB_644 v_508_128 23,76 23,06 24,51 lod 2.8 6.2
Champenoux_2015_nPriLBD_A4 Qrob_Chr02 2 s_1CP5DI_1183 s_1A63ZX_1277 25,35 24,63 26,18 lod 4.0 8.7
Champenoux_2015_nSecLBD_A4 Qrob_Chr02 2 s_1AN4ZM_1665 v_8587_238 18,52 18,89 18,27 lod 3.2 7.4

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 31   Mitochondrion 4 0.134 0.554 NON-PLANT 31