Protein : Qrob_P0130930.2 Q. robur
Protein Identifier  ? Qrob_P0130930.2 Organism . Name  Quercus robur
Score  0.0 Score Type  egn
Protein Description  (M=1) K09591 - probable steroid reductase DET2 [EC:1.3.99.-] Code Enzyme  EC:1.3.1.22
Gene Prediction Quality  validated Protein length 

Sequence

Length: 262  
Kegg Orthology  K09591
Paste the following link
Lists
This Protein isn't in any lists. Upload a list.

Sequence Feature Displayer

Protein Sequence Displayer

J Browse Displayer

0 Synonyms

8 GO Terms

Identifier Name Description
GO:0005737 cytoplasm All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0006629 lipid metabolic process The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity Catalysis of the reaction: a 3-oxo-5-alpha-steroid + acceptor = a 3-oxo-delta(4)-steroid + reduced acceptor.
GO:0008202 steroid metabolic process The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.

27 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pxb:103959591 1 261 + 261 none 89.69 291 80.84 7e-153 steroid 5-alpha-reductase DET2
blastp_kegg lcl|pmum:103338269 2 261 + 260 Gaps:1 100.00 259 82.63 2e-152 steroid 5-alpha-reductase DET2
blastp_kegg lcl|pper:PRUPE_ppa024349mg 2 261 + 260 Gaps:1 100.00 259 82.63 2e-152 hypothetical protein
blastp_kegg lcl|mdm:103433568 1 261 + 261 none 100.00 261 80.08 3e-152 steroid 5-alpha-reductase DET2
blastp_kegg lcl|mdm:103419376 1 261 + 261 none 100.00 261 79.69 1e-151 steroid 5-alpha-reductase DET2-like
blastp_kegg lcl|fve:101295242 2 261 + 260 Gaps:4 99.24 262 79.23 2e-146 steroid 5-alpha-reductase DET2-like
blastp_kegg lcl|rcu:RCOM_0085180 1 261 + 261 Gaps:2 100.00 263 74.90 4e-140 3-oxo-5-alpha-steroid 4-dehydrogenase putative (EC:1.3.99.5)
blastp_kegg lcl|cic:CICLE_v10013348mg 2 261 + 260 Gaps:7 100.00 259 77.22 4e-139 hypothetical protein
blastp_kegg lcl|cit:102609492 5 261 + 257 Gaps:7 96.60 265 77.73 3e-138 steroid 5-alpha-reductase DET2-like
blastp_kegg lcl|pop:POPTR_0016s11800g 1 260 + 260 Gaps:6 99.61 257 76.95 8e-136 POPTRDRAFT_576916 3-oxo-5-alpha-steroid 4-dehydrogenase family protein
blastp_uniprot_sprot sp|Q2QDF6|DET2_GOSHI 2 261 + 260 Gaps:6 100.00 258 72.09 9e-130 Steroid 5-alpha-reductase DET2 OS Gossypium hirsutum GN DET2 PE 1 SV 1
blastp_uniprot_sprot sp|Q38944|DET2_ARATH 4 261 + 258 Gaps:4 98.47 262 69.38 3e-127 Steroid 5-alpha-reductase DET2 OS Arabidopsis thaliana GN DET2 PE 1 SV 2
blastp_uniprot_sprot sp|Q5K2N1|DET2_SOLLC 1 261 + 261 Gaps:6 100.00 257 61.09 1e-111 Steroid 5-alpha-reductase DET2 OS Solanum lycopersicum GN DET2 PE 1 SV 1
blastp_uniprot_sprot sp|Q68FF9|S5A1_MOUSE 23 260 + 238 Gaps:16 90.98 255 43.10 2e-47 3-oxo-5-alpha-steroid 4-dehydrogenase 1 OS Mus musculus GN Srd5a1 PE 2 SV 2
blastp_uniprot_sprot sp|P24008|S5A1_RAT 14 260 + 247 Gaps:21 94.21 259 40.98 6e-46 3-oxo-5-alpha-steroid 4-dehydrogenase 1 OS Rattus norvegicus GN Srd5a1 PE 1 SV 2
blastp_uniprot_sprot sp|Q28891|S5A1_MACFA 19 261 + 243 Gaps:16 90.11 263 40.93 1e-44 3-oxo-5-alpha-steroid 4-dehydrogenase 1 OS Macaca fascicularis GN SRD5A1 PE 1 SV 1
blastp_uniprot_sprot sp|P18405|S5A1_HUMAN 19 261 + 243 Gaps:16 91.51 259 41.35 1e-44 3-oxo-5-alpha-steroid 4-dehydrogenase 1 OS Homo sapiens GN SRD5A1 PE 1 SV 1
blastp_uniprot_sprot sp|A5PJS2|S5A1_BOVIN 19 260 + 242 Gaps:22 92.61 257 40.76 1e-41 3-oxo-5-alpha-steroid 4-dehydrogenase 1 OS Bos taurus GN SRD5A1 PE 2 SV 1
blastp_uniprot_sprot sp|Q28892|S5A2_MACFA 1 261 + 261 Gaps:36 96.46 254 40.00 4e-38 3-oxo-5-alpha-steroid 4-dehydrogenase 2 OS Macaca fascicularis GN SRD5A2 PE 1 SV 1
blastp_uniprot_sprot sp|O18765|S5A2_PIG 51 261 + 211 Gaps:22 79.92 254 42.36 7e-38 3-oxo-5-alpha-steroid 4-dehydrogenase 2 OS Sus scrofa GN SRD5A2 PE 2 SV 2
rpsblast_cdd gnl|CDD|178015 1 261 + 261 Gaps:3 100.00 260 79.62 1e-125 PLN02392 PLN02392 probable steroid reductase DET2.
rpsblast_cdd gnl|CDD|111444 113 261 + 149 Gaps:4 99.33 150 53.69 1e-42 pfam02544 Steroid_dh 3-oxo-5-alpha-steroid 4-dehydrogenase. This family consists of 3-oxo-5-alpha-steroid 4-dehydrogenases EC:1.3.99.5 Also known as Steroid 5-alpha-reductase the reaction catalyzed by this enzyme is: 3-oxo-5-alpha-steroid + acceptor < > 3-oxo-delta(4)-steroid + reduced acceptor. The Steroid 5-alpha-reductase enzyme is responsible for the formation of dihydrotestosterone this hormone promotes the differentiation of male external genitalia and the prostate during fetal development. In humans mutations in this enzyme can cause a form of male pseudohermaphorditism in which the external genitalia and prostate fail to develop normally. A related enzyme is also found in plants is DET2 a steroid reductase from Arabidopsis. Mutations in this enzyme cause defects in light-regulated development.
rpsblast_cdd gnl|CDD|178708 135 261 + 127 Gaps:29 39.63 323 36.72 9e-14 PLN03164 PLN03164 3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal domain containing protein Provisional.
rpsblast_cdd gnl|CDD|178174 153 238 + 86 Gaps:6 27.27 308 39.29 9e-08 PLN02560 PLN02560 enoyl-CoA reductase.
rpsblast_kog gnl|CDD|36851 5 261 + 257 Gaps:17 98.05 257 44.44 3e-68 KOG1638 KOG1638 KOG1638 Steroid reductase [Lipid transport and metabolism].
rpsblast_kog gnl|CDD|36853 154 261 + 108 Gaps:4 36.18 304 41.82 1e-12 KOG1640 KOG1640 KOG1640 Predicted steroid reductase [Lipid transport and metabolism].
rpsblast_kog gnl|CDD|36852 142 260 + 119 Gaps:2 39.39 297 34.19 3e-12 KOG1639 KOG1639 KOG1639 Steroid reductase required for elongation of the very long chain fatty acids [Lipid transport and metabolism].

18 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
ProSiteProfiles 156 235 80 PS50244 "Reactome:REACT_22258" Steroid 5-alpha reductase C-terminal domain profile. IPR001104
Pfam 114 261 148 PF02544 "Reactome:REACT_22258" 3-oxo-5-alpha-steroid 4-dehydrogenase IPR001104
Phobius 31 49 19 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 79 98 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 232 261 30 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 68 78 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 170 206 37 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
PANTHER 14 261 248 PTHR10556 none none none
Phobius 99 117 19 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 1 11 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 12 30 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 50 67 18 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PANTHER 14 261 248 PTHR10556:SF2 none none none
Phobius 138 148 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 149 169 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PIRSF 1 261 261 PIRSF015596 "KEGG:00140+1.3.1.22","KEGG:00905+1.3.1.22","MetaCyc:PWY-6032","MetaCyc:PWY-7455","Reactome:REACT_15314","Reactome:REACT_22258" none IPR016636
Phobius 207 231 25 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 118 137 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none

6 Localization

Analysis Start End Length
TMHMM 78 100 22
TMHMM 209 231 22
TMHMM 148 170 22
TMHMM 115 132 17
TMHMM 7 29 22
TMHMM 49 71 22

5 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_A4 Qrob_Chr07 7 v_8327_222 s_1A4WGY_363 16,04 0 44,69 lod 2,6373 6,5
Bourran2_2014_nP_A4 Qrob_Chr11 11 s_1B58GB_1413 s_1A5BYY_1671 11,15 0 42,38 lod 1,8913 4,5
Bourran2_2015_nSeqBC_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 26,06 25,47 27,72 lod 3.6 7.1
Bourran2_2015_nEpis_A4 Qrob_Chr09 9 v_15847_485 v_8329_369 34,94 34,88 37,45 lod 3.1 7
Bourran2_2015_nEpiBC_A4 Qrob_Chr07 7 s_1DP9TW_798 v_8128_173 22,61 22,14 22,73 lod 3.1 8.5

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 165   Secretory pathway 2 0.870 0.068 NON-PLANT 165