| Analysis | rpsblast_cdd | Start | 113 |
| End | 261 | Strand | + |
| Length | 149 | Note | Gaps:4 |
| Hit Coverage | 99.33 | Hit Length | 150 |
| Hit Pident | 53.69 | E Val | 1e-42 |
| Hit Description | pfam02544 Steroid_dh 3-oxo-5-alpha-steroid 4-dehydrogenase. This family consists of 3-oxo-5-alpha-steroid 4-dehydrogenases EC:1.3.99.5 Also known as Steroid 5-alpha-reductase the reaction catalyzed by this enzyme is: 3-oxo-5-alpha-steroid + acceptor < > 3-oxo-delta(4)-steroid + reduced acceptor. The Steroid 5-alpha-reductase enzyme is responsible for the formation of dihydrotestosterone this hormone promotes the differentiation of male external genitalia and the prostate during fetal development. In humans mutations in this enzyme can cause a form of male pseudohermaphorditism in which the external genitalia and prostate fail to develop normally. A related enzyme is also found in plants is DET2 a steroid reductase from Arabidopsis. Mutations in this enzyme cause defects in light-regulated development. | Hit Pcons | 15.44 |
| Name | Qrob_P0130930.2 |
| Protein Identifier |
Organism . Name |
Score | Score Type | Protein Description | Alias (in v1) | Code Enzyme | Gene Prediction Quality |
|---|---|---|---|---|---|---|---|
| Qrob_P0130930.2 | Quercus robur | 0.0 | egn | (M=1) K09591 - probable steroid reductase DET2 [EC:1.3.99.-] | EC:1.3.1.22 | validated |
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