Protein : Qrob_P0069090.2 Q. robur
Protein Identifier  ? Qrob_P0069090.2 Organism . Name  Quercus robur
Score  14.1 Score Type  egn
Protein Description  (M=1) PTHR19229//PTHR19229:SF105 - ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A (ABCA) // SUBFAMILY NOT NAMED Code Enzyme  EC:3.6.3.25
Gene Prediction Quality  validated Protein length 

Sequence

Length: 81  
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0 Synonyms

5 GO Terms

Identifier Name Description
GO:0005524 ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0005215 transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:0016887 ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.

29 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|brp:103857992 9 75 + 67 Gaps:44 5.92 1876 49.55 7e-21 ABC transporter A family member 1
blastp_kegg lcl|aly:ARALYDRAFT_483249 9 73 + 65 Gaps:44 5.69 1914 50.46 8e-21 ATPase coupled to transmembrane movement of substances
blastp_kegg lcl|crb:CARUB_v10025445mg 9 75 + 67 Gaps:44 5.90 1881 48.65 2e-20 hypothetical protein
blastp_kegg lcl|tcc:TCM_024563 9 75 + 67 Gaps:44 5.89 1883 47.75 4e-20 ABC transporter family cholesterol/phospholipid flippase isoform 1
blastp_kegg lcl|pxb:103931655 7 75 + 69 Gaps:44 5.98 1889 44.25 5e-20 ABC transporter A family member 1-like
blastp_kegg lcl|pxb:103953179 7 75 + 69 Gaps:44 5.98 1889 44.25 5e-20 ABC transporter A family member 1-like
blastp_kegg lcl|mdm:103449760 7 75 + 69 Gaps:44 5.98 1889 44.25 6e-20 ABC transporter A family member 1
blastp_kegg lcl|cic:CICLE_v10004128mg 9 75 + 67 Gaps:44 5.86 1893 47.75 1e-19 hypothetical protein
blastp_kegg lcl|fve:101308109 9 75 + 67 Gaps:44 5.88 1888 46.85 1e-19 LOW QUALITY PROTEIN: ABC transporter A family member 1-like
blastp_kegg lcl|cit:102625041 9 75 + 67 Gaps:44 5.86 1893 47.75 1e-19 ABC transporter A family member 1-like
blastp_uniprot_sprot sp|Q84M24|AB1A_ARATH 9 73 + 65 Gaps:44 5.79 1882 49.54 2e-21 ABC transporter A family member 1 OS Arabidopsis thaliana GN ABCA1 PE 2 SV 2
blastp_uniprot_sprot sp|Q39GT7|NODI_BURS3 19 52 + 34 none 11.18 304 67.65 7e-08 Nod factor export ATP-binding protein I OS Burkholderia sp. (strain 383) GN nodI PE 3 SV 2
blastp_uniprot_sprot sp|Q63TX3|NODI_BURPS 19 52 + 34 none 11.18 304 67.65 3e-07 Nod factor export ATP-binding protein I OS Burkholderia pseudomallei (strain K96243) GN nodI PE 3 SV 2
blastp_uniprot_sprot sp|Q3JSQ0|NODI_BURP1 19 52 + 34 none 11.18 304 67.65 3e-07 Nod factor export ATP-binding protein I OS Burkholderia pseudomallei (strain 1710b) GN nodI PE 3 SV 2
blastp_uniprot_sprot sp|Q62K72|NODI_BURMA 19 52 + 34 none 11.18 304 67.65 3e-07 Nod factor export ATP-binding protein I OS Burkholderia mallei (strain ATCC 23344) GN nodI PE 3 SV 2
blastp_uniprot_sprot sp|Q9FLT8|AB12A_ARATH 9 53 + 45 none 4.91 917 53.33 4e-07 ABC transporter A family member 12 OS Arabidopsis thaliana GN ABCA12 PE 3 SV 1
blastp_uniprot_sprot sp|Q1BWI2|NODI_BURCA 19 52 + 34 none 11.18 304 64.71 5e-07 Nod factor export ATP-binding protein I OS Burkholderia cenocepacia (strain AU 1054) GN nodI PE 3 SV 1
blastp_uniprot_sprot sp|Q1PEH6|AB3A_ARATH 9 53 + 45 none 4.83 932 48.89 9e-07 ABC transporter A family member 3 OS Arabidopsis thaliana GN ABCA3 PE 2 SV 3
blastp_uniprot_sprot sp|P78363|ABCA4_HUMAN 9 73 + 65 Gaps:48 4.62 2273 32.38 9e-07 Retinal-specific ATP-binding cassette transporter OS Homo sapiens GN ABCA4 PE 1 SV 3
blastp_uniprot_sprot sp|Q9STT5|AB7A_ARATH 9 53 + 45 none 4.81 935 48.89 1e-06 ABC transporter A family member 7 OS Arabidopsis thaliana GN ABCA7 PE 3 SV 2
rpsblast_cdd gnl|CDD|73022 9 74 + 66 Gaps:48 48.18 220 31.13 5e-10 cd03263 ABC_subfamily_A The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases such as familial high-density lipoprotein (HDL) deficiency neonatal surfactant deficiency degenerative retinopathies and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells and therefore performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages..
rpsblast_cdd gnl|CDD|184124 19 52 + 34 none 11.11 306 67.65 6e-09 PRK13537 PRK13537 nodulation ABC transporter NodI Provisional.
rpsblast_cdd gnl|CDD|130256 20 53 + 34 none 11.26 302 58.82 7e-08 TIGR01188 drrA daunorubicin resistance ABC transporter ATP-binding subunit. This model describes daunorubicin resistance ABC transporter ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit An integral membrane protein a hydrophilic polypetpide which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins multidrug resistance protein etc.
rpsblast_cdd gnl|CDD|31326 19 53 + 35 none 11.95 293 54.29 2e-07 COG1131 CcmA ABC-type multidrug transport system ATPase component [Defense mechanisms].
rpsblast_cdd gnl|CDD|72989 18 53 + 36 none 20.81 173 41.67 2e-07 cd03230 ABC_DR_subfamily_A This family of ATP-binding proteins belongs to a multisubunit transporter involved in drug resistance (BcrA and DrrA) nodulation lipid transport and lantibiotic immunity. In bacteria and archaea these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryote systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif Q-loop and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins..
rpsblast_cdd gnl|CDD|33903 18 69 + 52 Gaps:16 22.67 300 39.71 3e-07 COG4152 COG4152 ABC-type uncharacterized transport system ATPase component [General function prediction only].
rpsblast_cdd gnl|CDD|73028 18 49 + 32 none 15.24 210 56.25 4e-07 cd03269 ABC_putative_ATPase This subfamily is involved in drug resistance nodulation lipid transport and bacteriocin and lantibiotic immunity. In eubacteria and archaea the typical organization consists of one ABC and one or two IMs. Eukaryote systems of the ABCA subfamily display ABC domains strongly similar to this family. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds like sugars ions peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif Q-loop and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins..
rpsblast_cdd gnl|CDD|73024 20 53 + 34 none 15.45 220 55.88 6e-07 cd03265 ABC_DrrA DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds like sugars ions peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif Q-loop and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins..
rpsblast_cdd gnl|CDD|184123 19 47 + 29 none 8.53 340 62.07 9e-07 PRK13536 PRK13536 nodulation factor exporter subunit NodI Provisional.

5 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 18 57 40 G3DSA:3.40.50.300 none none IPR027417
PANTHER 9 50 42 PTHR19229 none none IPR026082
SUPERFAMILY 19 52 34 SSF52540 none none IPR027417
PANTHER 9 50 42 PTHR19229:SF105 none none none
Pfam 25 56 32 PF00005 none ABC transporter IPR003439

0 Localization

2 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2014_rEpiBC_3P Qrob_Chr05 5 s_2GDU0O_517 s_1BT8O3_239 25,81 0 55,45 lod 2,2101 5,5

0 Targeting