Protein : Qrob_P0053050.2 Q. robur
Protein Identifier  ? Qrob_P0053050.2 Organism . Name  Quercus robur
Score  87.1 Score Type  egn
Protein Description  (M=2) 2.3.1.61 - Dihydrolipoyllysine-residue succinyltransferase. Code Enzyme  EC:2.3.1.61
Gene Prediction Quality  validated Protein length 

Sequence

Length: 466  
Kegg Orthology  K00658
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0 Synonyms

5 GO Terms

Identifier Name Description
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016746 transferase activity, transferring acyl groups Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).
GO:0006099 tricarboxylic acid cycle A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
GO:0004149 dihydrolipoyllysine-residue succinyltransferase activity Catalysis of the reaction: succinyl-CoA + dihydrolipoamide = CoA + S-succinyldihydrolipoamide.
GO:0045252 oxoglutarate dehydrogenase complex A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).

44 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pmum:103326427 36 465 + 430 Gaps:1 92.89 464 82.60 0.0 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 2 mitochondrial-like
blastp_kegg lcl|pop:POPTR_0011s09160g 36 465 + 430 Gaps:6 91.22 467 85.45 0.0 POPTRDRAFT_727965 2-oxoacid dehydrogenase family protein
blastp_kegg lcl|tcc:TCM_030840 35 465 + 431 Gaps:5 91.03 468 83.80 0.0 Dihydrolipoamide succinyltransferase
blastp_kegg lcl|pop:POPTR_0001s36710g 36 465 + 430 Gaps:1 91.12 473 84.45 0.0 POPTRDRAFT_642210 2-oxoacid dehydrogenase family protein
blastp_kegg lcl|cit:102622253 37 465 + 429 Gaps:2 90.85 470 84.07 0.0 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 1 mitochondrial-like
blastp_kegg lcl|cic:CICLE_v10008189mg 37 465 + 429 Gaps:2 90.85 470 83.84 0.0 hypothetical protein
blastp_kegg lcl|rcu:RCOM_1303600 36 465 + 430 Gaps:4 90.83 469 86.38 0.0 dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase putative (EC:2.3.1.61)
blastp_kegg lcl|sly:101268590 36 465 + 430 Gaps:6 91.03 468 83.57 0.0 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 2 mitochondrial-like
blastp_kegg lcl|sly:101258624 36 465 + 430 Gaps:5 92.52 468 79.91 0.0 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 1 mitochondrial-like
blastp_kegg lcl|sot:102604382 36 465 + 430 Gaps:6 91.03 468 83.33 0.0 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 2 mitochondrial-like
blastp_pdb 1scz_A 236 465 + 230 none 98.71 233 60.00 3e-98 mol:protein length:233 Dihydrolipoamide Succinyltransferase
blastp_pdb 1e2o_A 236 465 + 230 none 98.71 233 60.00 3e-98 mol:protein length:233 DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE
blastp_pdb 1c4t_C 236 465 + 230 none 98.71 233 60.00 3e-98 mol:protein length:233 PROTEIN (DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE
blastp_pdb 1c4t_B 236 465 + 230 none 98.71 233 60.00 3e-98 mol:protein length:233 PROTEIN (DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE
blastp_pdb 1c4t_A 236 465 + 230 none 98.71 233 60.00 3e-98 mol:protein length:233 PROTEIN (DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE
blastp_pdb 1b5s_E 222 463 + 242 Gaps:7 98.76 242 40.17 2e-47 mol:protein length:242 DIHYDROLIPOAMIDE ACETYLTRANSFERASE
blastp_pdb 1b5s_D 222 463 + 242 Gaps:7 98.76 242 40.17 2e-47 mol:protein length:242 DIHYDROLIPOAMIDE ACETYLTRANSFERASE
blastp_pdb 1b5s_C 222 463 + 242 Gaps:7 98.76 242 40.17 2e-47 mol:protein length:242 DIHYDROLIPOAMIDE ACETYLTRANSFERASE
blastp_pdb 1b5s_B 222 463 + 242 Gaps:7 98.76 242 40.17 2e-47 mol:protein length:242 DIHYDROLIPOAMIDE ACETYLTRANSFERASE
blastp_pdb 1b5s_A 222 463 + 242 Gaps:7 98.76 242 40.17 2e-47 mol:protein length:242 DIHYDROLIPOAMIDE ACETYLTRANSFERASE
blastp_uniprot_sprot sp|Q8H107|ODO2B_ARATH 45 465 + 421 Gaps:9 89.22 464 76.33 0.0 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 2 mitochondrial OS Arabidopsis thaliana GN At4g26910 PE 1 SV 2
blastp_uniprot_sprot sp|Q9FLQ4|ODO2A_ARATH 4 465 + 462 Gaps:24 95.69 464 73.42 0.0 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 1 mitochondrial OS Arabidopsis thaliana GN At5g55070 PE 1 SV 1
blastp_uniprot_sprot sp|Q90512|ODO2_TAKRU 90 465 + 376 Gaps:12 90.95 409 54.57 5e-125 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex mitochondrial (Fragment) OS Takifugu rubripes GN dlst PE 3 SV 1
blastp_uniprot_sprot sp|Q6FYD4|ODO2_BARQU 96 465 + 370 Gaps:50 98.54 410 47.77 2e-121 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex OS Bartonella quintana (strain Toulouse) GN sucB PE 3 SV 1
blastp_uniprot_sprot sp|Q92J43|ODO2_RICCN 92 465 + 374 Gaps:29 99.49 395 48.35 2e-120 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex OS Rickettsia conorii (strain ATCC VR-613 / Malish 7) GN sucB PE 3 SV 1
blastp_uniprot_sprot sp|P11179|ODO2_BOVIN 90 465 + 376 Gaps:18 84.84 455 51.04 3e-120 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex mitochondrial OS Bos taurus GN DLST PE 1 SV 2
blastp_uniprot_sprot sp|Q1RHI5|ODO2_RICBR 92 465 + 374 Gaps:28 99.50 400 48.49 4e-120 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex OS Rickettsia bellii (strain RML369-C) GN sucB PE 3 SV 1
blastp_uniprot_sprot sp|Q869Y7|ODO2_DICDI 82 465 + 384 Gaps:24 85.19 439 51.87 4e-120 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex mitochondrial OS Dictyostelium discoideum GN odhB PE 1 SV 1
blastp_uniprot_sprot sp|Q4UKI7|ODO2_RICFE 92 465 + 374 Gaps:37 99.50 401 47.87 4e-119 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex OS Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) GN sucB PE 3 SV 1
blastp_uniprot_sprot sp|Q8GCY1|ODO2_BARVB 96 465 + 370 Gaps:35 98.54 411 47.90 9e-118 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex OS Bartonella vinsonii subsp. berkhofii GN sucB PE 3 SV 1

12 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
SUPERFAMILY 235 464 230 SSF52777 none none none
Pfam 234 463 230 PF00198 none 2-oxoacid dehydrogenases acyltransferase (catalytic domain) IPR001078
Gene3D 91 184 94 G3DSA:2.40.50.100 none none none
TIGRFAM 198 464 267 TIGR01347 "KEGG:00020+2.3.1.61","KEGG:00310+2.3.1.61","MetaCyc:PWY-5084","UniPathway:UPA00868" sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex IPR006255
Pfam 96 165 70 PF00364 none Biotin-requiring enzyme IPR000089
Coils 345 366 22 Coil none none none
PANTHER 57 465 409 PTHR23151 none none none
PANTHER 57 465 409 PTHR23151:SF8 none none none
ProSiteProfiles 91 166 76 PS50968 none Biotinyl/lipoyl domain profile. IPR000089
ProSitePatterns 116 145 30 PS00189 none 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. IPR003016
SUPERFAMILY 92 183 92 SSF51230 none none IPR011053
Gene3D 226 463 238 G3DSA:3.30.559.10 none none IPR023213

0 Localization

10 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran2_2014_aSeqBC_A4 Qrob_Chr08 8 v_15999_278 v_AP13YL15_395 32,52 4,22 57,22 lod 2,7561 6,7
Bourran2_2014_nFork*_A4 Qrob_Chr08 8 PIE175 s_1CD7GJ_1398 31,22 5,24 57,24 lod 2,6724 6,8
Bourran2_2014_nLBD*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,25 0 35,55 lod 2,5951 6
Bourran2_2014_nP*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,19 0 31,97 lod 2,8472 6
Bourran2_2014_nPriLBD_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,36 0 30,43 lod 2,5806 5,1
Champenoux_2015_nSeqBC_A4 Qrob_Chr08 8 v_AD7YD13_501 s_1A7IED_780 43,44 43,42 43,99 lod 3.7 8.9
Bourran2_2014_nEpis*_3P Qrob_Chr08 8 s_1DA4QW_688 s_1DNI7D_820 17,96 0 37,75 lod 2,9745 7,5
Bourran2_2014_nPriBD_3P Qrob_Chr11 11 v_11486_194 s_1AT3E_2335 5,54 0,4 20,6 lod 2,6345 5,9

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 16   Secretory pathway 5 0.686 0.052 NON-PLANT 16